Search Results - "Li, Tindy"
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Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo
Published in Bioorganic & medicinal chemistry (15-02-2019)“…[Display omitted] The antioxidant natural product sulforaphane (SFN) is an oil with poor aqueous and thermal stability. Recent work with SFN has sought to…”
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2
BAY 65-6207 Is a Glucose-Dependent Insulin Secretagogue In Vivo
Published in Diabetes (New York, N.Y.) (01-06-2005)Get full text
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Asymmetry by Electrophilic Rearrangement of Symmetric 2-Pyridone Photodimers
Published in Organic letters (24-11-2005)“…Halogenation of achiral trans-2-pyridone photodimers results in 1,3-migration of an amide nitrogen and formation of a chiral structure with six stereogenic…”
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Substituted aminobenzimidazole pyrimidines as cyclin-dependent kinase inhibitors
Published in Bioorganic & medicinal chemistry letters (15-04-2005)“…Substituted aminobenzimidazole pyrimidines were synthesized and are shown to display potent biochemical activity against CDK1. Docking studies carried out with…”
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Polyquinanes by [4 + 4] Cycloaddition−Transannular Cyclization
Published in Organic letters (12-07-2001)“…Photocycloaddition of 2-pyridones yields a rigid polycyclic product containing a 1,5-cyclooctadiene. The cis isomer, with the alkenes in close proximity,…”
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Substituted indanylacetic acids as PPAR-α–γ activators
Published in Bioorganic & medicinal chemistry letters (15-01-2006)“…A series of substituted indanylacetic acids were prepared which showed a spectrum of agonist activity against PPAR nuclear receptor subtypes. A series of…”
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Pyridone Annulation by 4 + 2 Coupling of Dienolates with Nitriles and Nitrile Equivalents. A Solution to the Acetonitrile Problem
Published in Journal of organic chemistry (05-10-2001)Get full text
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