Search Results - "Li, Shiri"
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The Role of the Nrf2 Signaling in Obesity and Insulin Resistance
Published in International journal of molecular sciences (22-09-2020)“…Obesity, a metabolic disorder characterized by excessive accumulation of adipose tissue, has globally become an increasingly prevalent disease. Extensive…”
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2
Dose-dependent effects of necrostatin-1 supplementation to tissue culture media of young porcine islets
Published in PloS one (07-12-2020)“…Previous studies have shown that necrostatin-1 (Nec-1) supplementation improved the viability of murine islets following exposure to nitric oxide, increased…”
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3
Venous thromboembolism in common laparoscopic abdominal surgical operations
Published in The American journal of surgery (01-12-2017)“…Venous thromboembolism (VTE) is potentially a serious postoperative complication. We examined the incidence and outcome of VTE among different laparoscopic…”
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4
The effect of Nrf2 pathway activation on human pancreatic islet cells
Published in PloS one (25-06-2015)“…Pancreatic islets are known to contain low level of antioxidants that renders them vulnerable to oxidative stress. Nrf2 is the master regulator of numerous…”
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5
Triple-Therapy of Peritoneal Metastasis-Partial-Dehydration under Hyperthermic Condition Combined with Chemotherapy: The First Preliminary In-Vitro Results
Published in Pharmaceuticals (Basel, Switzerland) (18-05-2023)“…A newly introduced combination of intraperitoneal dehydration and hyperthermia has recently been shown to be feasible and cytotoxic for colon cancer cells in…”
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6
Necrostatin-1 Supplementation to Islet Tissue Culture Enhances the In-Vitro Development and Graft Function of Young Porcine Islets
Published in International journal of molecular sciences (04-08-2021)“…Pre-weaned porcine islets (PPIs) represent an unlimited source for islet transplantation but are functionally immature. We previously showed that necrostatin-1…”
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7
The Onset of In-Vivo Dehydration in Gas -Based Intraperitoneal Hyperthermia and Its Cytotoxic Effects on Colon Cancer Cells
Published in Frontiers in oncology (29-06-2022)“…Background Peritoneal metastasis (PM) is an ongoing challenge in surgical oncology. Current therapeutic options, including intravenous and intraperitoneal…”
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8
In-vivo thermodynamic exploration of gas-based intraperitoneal hyperthermia
Published in Frontiers in oncology (29-08-2022)“…Background While hyperthermic intraperitoneal (i.p) applications are highly efficient in treating peritoneal metastases (PM), they are currently limited to…”
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Exploring Insulin Production Following Alveolar Islet Transplantation (AIT)
Published in International journal of molecular sciences (01-10-2021)“…Recent studies have demonstrated the feasibility of islet implantation into the alveoli. However, until today, there are no data on islet behavior and…”
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Safety, feasibility, and application of intraperitoneal gas-based hyperthermia beyond 43°C in the treatment of peritoneal metastasis: An in-vivo pilot study
Published in Frontiers in oncology (11-10-2022)“…43°Celsius (C) is currently the highest temperature used in the treatment of peritoneal metastasis (PM). Despite sufficient data on water- based hyperthermic…”
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Intraoperative parameters and postoperative follow-up of foam-based intraperitoneal chemotherapy (FBIC)
Published in Frontiers in pharmacology (14-11-2023)“…Background: For decades, intraperitoneal chemotherapy (IPC) has been delivered into the abdominal cavity as a liquid solution. Recently the concept of foam as…”
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12
Potential Benefits of Nrf2/Keap1 Targeting in Pancreatic Islet Cell Transplantation
Published in Antioxidants (16-04-2020)“…Permanent pancreatic islet cell destruction occurs in type 1 diabetes mellitus (T1DM) through the infiltration of inflammatory cells and cytokines. Loss of…”
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13
First In Vivo Applicational Data of Foam-Based Intrathoracic Chemotherapy (FBiTC) in a Swine Model
Published in Pharmaceuticals (Basel, Switzerland) (27-12-2023)“…For decades, both intraperitoneal and pleural chemotherapy (IPC) have been delivered as a liquid solution. Recent studies suggest that foam carriers outperform…”
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14
Drug Distribution and Penetration of Foam-Based Intraperitoneal Chemotherapy (FBIC)
Published in Pharmaceuticals (Basel, Switzerland) (01-10-2023)“…For decades, intraperitoneal chemotherapy (IPC) was used as a liquid solution for the treatment of peritoneal metastasis. Due to its advantageous physical…”
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15
Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-inflammatory Pathways
Published in Antioxidants (24-04-2020)“…Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous…”
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16
Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation
Published in Communications biology (03-06-2021)“…Foreign body response (FBR) to biomaterials compromises the function of implants and leads to medical complications. Here, we report a hybrid alginate…”
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Dimethyl fumarate protects pancreatic islet cells and non-endocrine tissue in L-arginine-induced chronic pancreatitis
Published in PloS one (08-09-2014)“…Chronic pancreatitis (CP) is a progressive disorder resulting in the destruction and fibrosis of the pancreatic parenchyma which ultimately leads to impairment…”
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Islet Transplantation in the Lung via Endoscopic Aerosolization: Investigation of Feasibility, Islet Cluster Cell Vitality, and Structural Integrity
Published in Cell transplantation (01-01-2020)“…Aerosolized drug delivery has recently attracted much attention as a possible new tool for the delivery of complex nanoparticles. This study aims to…”
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Exploring the potential of taurolidine in inducing mobilization and detachment of colon cancer cells: a preliminary in-vitro study
Published in BMC pharmacology & toxicology (13-06-2022)“…Recently, taurolidine has been intensively studied on a variety of in-vitro cancer cell-lines and first data exhibit encouraging antitumoral effects. While the…”
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20
Association of pre-operative estimated GFR on post-operative pulmonary complications in laparoscopic surgeries
Published in Scientific reports (26-07-2017)“…Despite a large body of evidence showing the pandemic of chronic kidney disease, the impact of pre-operative kidney function on the risk of post-operative…”
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