Search Results - "Li, Ruoyan"
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Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2019)“…The reactivation of quiescent cells to proliferate is fundamental to tissue repair and homeostasis in the body. Often referred to as the G0 state, quiescence…”
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2
Macroscopic somatic clonal expansion in morphologically normal human urothelium
Published in Science (American Association for the Advancement of Science) (02-10-2020)“…Knowledge of somatic mutation accumulation in normal cells, which is essential for understanding cancer development and evolution, remains largely lacking. In…”
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3
A body map of somatic mutagenesis in morphologically normal human tissues
Published in Nature (London) (16-09-2021)“…Somatic mutations that accumulate in normal tissues are associated with ageing and disease 1 , 2 . Here we performed a comprehensive genomic analysis of 1,737…”
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4
Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma
Published in Nature communications (03-03-2022)“…Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of non-Hodgkin lymphoma distinguished by the presence of clonal malignant T cells. The…”
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Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes
Published in Cancer cell (10-06-2019)“…We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate,…”
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Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma
Published in Cell research (01-11-2020)“…Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignancy with a complex tumor ecosystem. How the interplay between tumor cells, EBV,…”
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7
Aneuploid embryonic stem cells drive teratoma metastasis
Published in Nature communications (05-02-2024)“…Aneuploidy, a deviation of the chromosome number from euploidy, is one of the hallmarks of cancer. High levels of aneuploidy are generally correlated with…”
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Author Correction: Aneuploid embryonic stem cells drive teratoma metastasis
Published in Nature communications (15-10-2024)Get full text
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9
Spatial clustering and common regulatory elements correlate with coordinated gene expression
Published in PLoS computational biology (01-03-2019)“…Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a…”
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10
Deformation Mechanisms of Inorganic Thermoelectric Materials with Plasticity
Published in Advanced energy and sustainability research (01-01-2024)“…Flexible inorganic thermoelectric (TE) materials are beneficial to the development of wireless wearable devices due to their plasticity and high performance…”
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11
Single-cell transcriptomics of immune cells in lymph nodes reveals their composition and alterations in functional dynamics during the early stages of bubonic plague
Published in Science China. Life sciences (2023)“…Bubonic plague caused by Yersinia pestis is highly infectious and often fatal. Characterization of the host immune response and its subsequent suppression by…”
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12
Effect of vibrational frequency on alfalfa opening compression process
Published in Bioresources (01-11-2022)“…To reveal the action mechanism of vibration frequency in alfalfa opening compression, a self-developed vibration compression test system was used to evaluate…”
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13
Single cell sequencing: technique, application, and future development
Published in Science bulletin (Beijing) (01-01-2015)“…The progression of next generation sequencing is continuously changing the landscape of genomic, transcriptomic, and epigenomic studies. Particularly, advances…”
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14
Experimental study on heat transfer of alfalfa during the vibration-assisted compression
Published in Bioresources (01-02-2023)“…Compression alfalfa into briquettes is an effective way to solve the problem of storage and transportation. In the process of compression, heat is generated,…”
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15
Single-cell DNA methylome analysis of circulating tumor cells
Published in Chinese journal of cancer research (30-06-2021)“…OBJECTIVEPrevious investigations of circulating tumor cells (CTCs) have mainly focused on their genomic or transcriptomic features, leaving their epigenetic…”
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16
Role of grain size in the evolution of stress-induced martensite and the tensile deformation behavior of Ti-7333 alloy
Published in Journal of materials research and technology (01-07-2024)“…The evolution of martensite and the tensile deformation behavior of Ti-7333 alloy with different β grain size was studied. It is found that the β grain size…”
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17
Removal behavior of Zn and alkalis from blast furnace dust in pre-reduction sinter process
Published in Green processing and synthesis (12-07-2023)“…In this study, iron concentrate and blast furnace dust were used as raw materials, and graphite was used as a reducing agent for mixing and briquetting. The…”
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18
Hyperprogression of cutaneous T cell lymphoma after anti-PD-1 treatment
Published in JCI insight (22-02-2023)“…BACKGROUNDImmune checkpoint blockade is an emerging treatment for T cell non-Hodgkin's lymphoma (T-NHL), but some patients with T-NHL have experienced…”
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Small needle-knife versus extracorporeal shock wave therapy for the treatment of plantar fasciitis: A systematic review and meta-analysis
Published in Heliyon (15-01-2024)“…Plantar fasciitis (PF) is the most common cause of chronic heel pain among adults. Extracorporeal shock wave therapy (ESWT) is the recommended in the current…”
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20
Severe chronic osteomyelitis caused by Morganella morganii with high population diversity
Published in International journal of infectious diseases (01-09-2016)“…Highlights • A case of severe chronic osteomyelitis caused by Morganella morganii and lasting for approximately 30 years is reported. • The pathogen was…”
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