Search Results - "Li, Ronald H L"

Evaluation of autoantibodies to desmoglein-2 in dogs with and without cardiac disease by Walker, Ashley L., Li, Ronald H. L., Nguyen, Nghi, Jauregui, Carina E., Meurs, Kathryn M., Gagnon, Allison L., Stern, Joshua A.

“…Autoantibodies to desmoglein-2 have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC) in people. ARVC is a common disease in the…”
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Naturally occurring canine laminopathy leading to a dilated and fibrosing cardiomyopathy in the Nova Scotia Duck Tolling Retriever by Bannasch, Danika L., Oertle, Danielle T., Vo, Julia, Batcher, Kevin L., Stern, Joshua A., Kaplan, Joanna L., Li, Ronald H. L., Madden, Indiana E., Christen, Matthias, Leeb, Tosso, Joshi, Nikhil

“…Dilated cardiomyopathy (DCM) is characterized by decreased systolic function and dilation of one or both ventricles, often leading to heart failure or sudden…”
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Canine platelets express functional Toll-like receptor-4: lipopolysaccharide-triggered platelet activation is dependent on adenosine diphosphate and thromboxane A2 in dogs by Li, Ronald H L, Nguyen, Nghi, Tablin, Fern

“…Functional Toll-like receptor 4 (TLR4) has been characterized in human and murine platelets indicating that platelets play a role in inflammation and…”
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A novel approach to identifying and quantifying neutrophil extracellular trap formation in septic dogs using immunofluorescence microscopy by Li, Ronald H L, Johnson, Lynelle R, Kohen, Casey, Tablin, Fern

“…Canine neutrophils release neutrophil extracellular traps (NETs) in response to lipopolysaccharide but NETs from clinical septic dogs had not been identified…”
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A Comparative Review of Neutrophil Extracellular Traps in Sepsis by Li, Ronald H L, Tablin, Fern

“…Sepsis is the leading cause of critical illness and mortality in human beings and animals. Neutrophils are the primary effector cells of innate immunity during…”
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Cats with thermal burn injuries from California wildfires show echocardiographic evidence of myocardial thickening and intracardiac thrombi by Sharpe, Ashley N., Gunther-Harrington, Catherine T., Epstein, Steven E., Li, Ronald H. L., Stern, Joshua A.

“…Recent increases in the prevalence and severity of wildfires in some regions have resulted in an increased frequency of veterinary burn patients. Few studies…”
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Platelet hyperresponsiveness and increased platelet‐neutrophil aggregates in dogs with myxomatous mitral valve disease and pulmonary hypertension by Duler, Laetitia, Visser, Lance, Nguyen, Nghi, Johnson, Lynelle R., Stern, Joshua A., Li, Ronald H. L.

“…Background Pulmonary hypertension (PH) in dogs with myxomatous mitral valve disease (MMVD) is caused by increased pulmonary venous pressure. Thrombosis,…”
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Circulating neutrophil extracellular traps in cats with hypertrophic cardiomyopathy and cardiogenic arterial thromboembolism by Li, Ronald H. L., Fabella, Arianne, Nguyen, Nghi, Kaplan, Joanna L., Ontiveros, Eric, Stern, Joshua A.

“…Background Cats with hypertrophic cardiomyopathy (HCM) are at risk of cardiogenic arterial thromboembolism (CATE). Neutrophil extracellular traps (NETs) may be…”
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A genetic polymorphism in P2RY1 impacts response to clopidogrel in cats with hypertrophic cardiomyopathy by Ueda, Yu, Li, Ronald H. L., Nguyen, Nghi, Ontiveros, Eric S., Kovacs, Samantha L., Oldach, Maureen S., Vernau, Karen M., Court, Michael H., Stern, Joshua A.

“…Clopidogrel is converted to its active metabolite by cytochrome P450 isoenzymes and irreversibly inhibits platelet activation by antagonizing the…”
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A novel ITGA2B double cytosine frameshift variant (c.1986_1987insCC) leads to Glanzmann's thrombasthenia in a cat by Rivas, Victor N., Tan, Avalene W. K., Shaverdian, Meg, Nguyen, Nghi P., Wouters, Jalena R., Stern, Joshua A., Li, Ronald H. L.

“…Background Glanzmann's thrombasthenia (GT) is a congenital platelet disorder affecting approximately 1:1 000 000 people globally and characterized by impaired…”
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Synergistic inhibitory effects of clopidogrel and rivaroxaban on platelet function and platelet‐dependent thrombin generation in cats by Lo, Sara T., Li, Ronald H. L., Georges, Catherine J., Nguyen, Nghi, Chen, Cheyenne K., Stuhlmann, Claire, Oldach, Maureen Sigmund, Rivas, Victor Noel, Fousse, Samantha, Harris, Samantha P., Stern, Joshua A.

“…Background Dual antithrombotic treatment (DAT) with clopidogrel and rivaroxaban sometimes is prescribed to cats with hypertrophic cardiomyopathy at risk of…”
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Evaluation of clopidogrel response in healthy cats using a novel viscoelastic test and thromboelastography by Rosati, Tommaso, Jandrey, Karl E, Stern, Joshua A, Nguyen, Nghi, Li, Ronald H L

“…Cats with cardiomyopathy face an increased risk of arterial thromboembolism (ATE). Although clopidogrel is frequently utilized to mitigate this risk, feline…”
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Evaluation of thrombin generation in dogs administered clopidogrel by Rank, Kaitlyn, Lynch, Alex M., Ruterbories, Laura K., Li, Ronald H. L., Ueda, Yu

“…IntroductionThe antiplatelet effect of clopidogrel can vary between patients. A modified thromboelastography (TEG) protocol (TEG-Platelet Mapping assay®…”
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Case report: Disseminated intravascular coagulation in a dog following treatment with melarsomine for Dirofilaria immitis by Philp, Helen S, Farrell, Kate S, Li, Ronald H L

“…Disseminated intravascular coagulation following melarsomine therapy for is reported in a 9-year-old female intact pit bull-type dog. The dog had been…”
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Lipopolysaccharide-Activated Canine Platelets Upregulate High Mobility Group Box-1 via Toll-Like Receptor 4 by Li, Ronald H. L., Hommel, Caelin, Nguyen, Nghi

“…High mobility group box-1 (HMGB1) and the toll-like receptor 4 (TLR4) axis is a key mediator of inflammation. Platelet-derived high mobility group box-1…”
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Assessment of P2Y12 Inhibition by Clopidogrel in Feline Platelets Using Flow Cytometry Quantification of Vasodilator-Stimulated Phosphoprotein Phosphorylation by Li, Ronald H. L., Nguyen, Nghi, Rosati, Tommaso, Jandrey, Karl

“…The primary objective of this study was to evaluate a novel flow cytometry-based assay of quantifying platelet phosphorylation of vasodilator-stimulated…”
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Platelet Priming and Activation in Naturally Occurring Thermal Burn Injuries and Wildfire Smoke Exposure Is Associated With Intracardiac Thrombosis and Spontaneous Echocardiographic Contrast in Feline Survivors by Tan, Avalene W. K., Li, Ronald H. L., Ueda, Yu, Stern, Joshua A., Hussain, Mehrab, Haginoya, Satoshi, Sharpe, Ashely N., Gunther-Harrington, Catherine T., Epstein, Steven E., Nguyen, Nghi

“…Wildfires pose a major health risk for humans, wildlife, and domestic animals. We previously discovered pathophysiologic parallels between domestic cats with…”
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Clinical, Diagnostic, and Imaging Findings in Three Juvenile Dogs With Paraspinal Hyperesthesia or Myelopathy as a Consequence of Hemophilia A: A Case Report by Fowler, Kayla M, Bolton, Timothy A, Rossmeisl, John H, Arendse, Avril U, Vernau, Karen M, Li, Ronald H L, Parker, Rell L

“…Three juvenile dogs presented with an acute onset of paraspinal hyperesthesia and/or neurologic deficits. These dogs underwent anesthesia for MRI and…”
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Lipopolysaccharide-induced neutrophil extracellular trap formation in canine neutrophils is dependent on histone H3 citrullination by peptidylarginine deiminase by Li, Ronald H.L., Ng, Geena, Tablin, Fern

“…•E. coli LPS induces canine neutrophils to produce NETs.•NETs consist of cell-free DNA, myeloperoxidase and citrullinated histone H3.•Histone…”
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Neutrophil-Extracellular Traps, Cell-Free DNA, and Immunothrombosis in Companion Animals: A Review by Goggs, Robert, Jeffery, Unity, LeVine, Dana N., Li, Ronald H. L.

“…Immunothrombosis is a potentially beneficial physiological process that aids innate immunity and host defense against pathogen invasion. However, this process…”
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