Search Results - "Li, Paul C. H."

The genetic authentication of Panax ginseng and Panax quinquefolius based on using single nucleotide polymorphism (SNP) conducted in a nucleic acid test chip by Oberc, Christopher, Sedighi, Abootaleb, Li, Paul C. H.

“…Panax ginseng and Panax quinquefolius , which are commonly called Chinese ginseng and American ginseng respectively, have different medicinal properties and…”
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Dielectrophoretic Microfluidic Chip Enables Single-Cell Measurements for Multidrug Resistance in Heterogeneous Acute Myeloid Leukemia Patient Samples by Khamenehfar, Avid, Gandhi, Maher K, Chen, Yuchun, Hogge, Donna E, Li, Paul C. H

“…The front-line treatment for adult acute myeloid leukemia (AML) is anthracycline-based combination chemotherapy. However, treatment outcomes remain suboptimal…”
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Study of flow behaviors on single-cell manipulation and shear stress reduction in microfluidic chips using computational fluid dynamics simulations by Shen, Feng, Li, XiuJun, Li, Paul C. H.

“…Various single-cell retention structures (SCRSs) were reported for analysis of single cells within microfluidic devices. Undesirable flow behaviors within…”
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Same-Single-Cell Analysis for the Study of Drug Efflux Modulation of Multidrug Resistant Cells Using a Microfluidic Chip by Li, XiuJun, Ling, Victor, Li, Paul C. H

“…Since multidrug resistance (MDR) is a major cause of failure in cancer chemotherapy, we report a microfluidic approach combined with the same-single-cell…”
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NanoHDA： A nanoparticle-assisted isothermal amplification technique for genotyping assays by Sedighi, Abootaleb, Oberc, Christopher, Whitehall, Vicki, Li, Paul C. H.

“…Isothermal methods, such as helicase-dependent amplification （HDA）, have an advantage over polymerase chain reaction for DNA amplification owing to their ease…”
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Microfluidic DNA microarray analysis: A review by Wang, Lin, Li, Paul C.H.

“…Microarray DNA hybridization techniques have been used widely from basic to applied molecular biology research. Generally, in a DNA microarray, different probe…”
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Enhanced destabilization of mismatched DNA using gold nanoparticles offers specificity without compromising sensitivity for nucleic acid analyses by Sedighi, Abootaleb, Whitehall, Vicki, Li, Paul C. H.

“…Here, we report a method that uses gold nanoparticles （AuNPs） to enhance the specificity of DNA hybridization without reducing its detection sensitivity. The…”
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Nucleic acid amplification test (NAAT) conducted in a microfluidic chip to differentiate between various ginseng species by Oberc, Christopher, Sojoudi, Parsa, Li, Paul C H

“…and have different medicinal properties and market values; however, they can be difficult to distinguish from one another based on physical appearances alone…”
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Construction of an Array of Photonic Crystal Films for Visual Differentiation of Water/Ethanol Mixtures by Heshmat, Mohammad, Li, Paul C. H

“…A photonic crystal film (PCF) which consists of a porous layered structure with a highly ordered periodic arrangement of nanopores has been used to…”
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Flexible Microarray Construction and Fast DNA Hybridization Conducted on a Microfluidic Chip for Greenhouse Plant Fungal Pathogen Detection by Wang, Lin, Li, Paul C. H

“…This study employed a microfluidic method in which probe creation does not require pin-spotting and fast hybridization is conducted on the same microarray chip…”
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Microfluidic Selection and Retention of a Single Cardiac Myocyte, On-Chip Dye Loading, Cell Contraction by Chemical Stimulation, and Quantitative Fluorescent Analysis of Intracellular Calcium by Li, Xiujun, Li, Paul C. H

“…A microfluidic method to study the contraction of a single cardiac myocyte (heart muscle cell) has been developed. This method integrates various single-cell…”
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A simple and fast microfluidic approach of same-single-cell analysis (SASCA) for the study of multidrug resistance modulation in cancer cells by Li, XiuJun, Chen, Yuchun, Li, Paul C H

“…Due to the cellular heterogeneity in multidrug resistance (MDR) cell populations, positive drug effects on the modulation of MDR can be obscured in…”
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Integration of laminar flow extraction and capillary electrophoretic separation in one microfluidic chip for detection of plant alkaloids in blood samples by Hu, Yingzhi, Peng, Huaidong, Yan, Youshao, Guan, Shuyu, Wang, Shumei, Li, Paul C.H., Sun, Yue

“…The design, construction and testing for integration of liquid-liquid extraction (EX) and capillary electrophoretic (CE) separation on one glass microchip was…”
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A Proposed Mechanism of the Influence of Gold Nanoparticles on DNA Hybridization by Sedighi, Abootaleb, Li, Paul C. H, Pekcevik, Idah C, Gates, Byron D

“…A combination of gold nanoparticles (AuNPs) and nucleic acids has been used in biosensing applications. However, there is a poor fundamental understanding of…”
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Fungal pathogenic nucleic acid detection achieved with a microfluidic microarray device by Wang, Lin, Li, Paul C.H., Yu, Hua-Zhong, Parameswaran, Ash M.

“…Detection of polymerase chain reaction (PCR) products obtained from cultured greenhouse fungal pathogens, Botrytis cinerea and Didymella bryoniae has been…”
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Transport, Manipulation, and Reaction of Biological Cells On-Chip Using Electrokinetic Effects by Li, Paul C. H, Harrison, D. Jed

“…A microfluidic system was fabricated on a glass chip to study mobilization of biological cells on-chip. Electroosmotic and/or electrophoretic pumping were used…”
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Dielectrophoretic trapping of single leukemic cells using the conventional and compact optical measurement systems by Sharifi Noghabi, Hamideh, Soo, Mandy, Khamenehfar, Avid, Li, Paul C.H.

“…Here, we report a microfluidic same‐single‐cell analysis to study the inhibition of multidrug resistance due to drug efflux on single leukemic cells. Drug…”
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A rotating microfluidic array chip for staining assays by Chen, Hong, Li, XiuJun, Wang, Lin, Li, Paul C.H.

“…We have developed a microfluidic method to construct an array on a circular disk for staining assays. In this method, convenient centrifugal liquid pumping has…”
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Magnetic Droplet Microfluidics as a Platform for the Concentration of [18F]Fluoride and Radiosynthesis of Sulfonyl [18F]Fluoride by Fiel, Somewhere A, Yang, Hua, Schaffer, Paul, Weng, Samuel, Inkster, James A. H, Wong, Michael C. K, Li, Paul C. H

“…The radioisotope 18F is often considered the best choice for positron emission tomography (PET) owing to its desirable chemical and radiochemical properties…”
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Artesunate derived from traditional Chinese medicine induces DNA damage and repair by Li, Paul C H, Lam, Elena, Roos, Wynand P, Zdzienicka, Malgorzata Z, Kaina, Bernd, Efferth, Thomas

“…Artesunate is a semisynthetic derivative from artemisinin, a natural product from the Chinese herb Artemisia annua L. It exerts antimalarial activity, and,…”
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