Search Results - "Li, Ming D"

Effect of Cigarette Smoke on Gut Microbiota: State of Knowledge by Gui, Xiaohua, Yang, Zhongli, Li, Ming D.

“…Cigarette smoke is a representative source of toxic chemical exposures to humans, and the adverse consequences of cigarette smoking are mediated by its effect…”
Get full text

Establishment of a Strong Link Between Smoking and Cancer Pathogenesis through DNA Methylation Analysis by Ma, Yunlong, Li, Ming D.

“…Smoking is a well-documented risk factor in various cancers, especially lung cancer. In the current study, we tested the hypothesis that abnormal DNAm loci…”
Get full text

CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies by Hu, Yongxian, Li, Jingjing, Ni, Fang, Yang, Zhongli, Gui, Xiaohua, Bao, Zhiwei, Zhao, Houli, Wei, Guoqing, Wang, Yiyun, Zhang, Mingming, Hong, Ruimin, Wang, Linqin, Wu, Wenjun, Mohty, Mohamad, Nagler, Arnon, Chang, Alex H., van den Brink, Marcel R. M., Li, Ming D., Huang, He

“…Immunotherapy utilizing chimeric antigen receptor T cell (CAR-T) therapy holds promise for hematologic malignancies, however, response rates and associated…”
Get full text

Editorial: Rising stars in molecular psychiatry by Yang, Zhongli, Li, Ming D

Get full text

Differential Allelic Expression of Dopamine D1 Receptor Gene ( DRD1 ) Is Modulated by microRNA miR-504 by Huang, Weihua, Li, Ming D

“…Background Previously, we reported that dopamine D1 receptor gene ( DRD1 ) is associated with nicotine dependence (ND) and demonstrated that two alleles (A and…”
Get full text

Long-term high-fat diet induces hippocampal microvascular insulin resistance and cognitive dysfunction by Fu, Zhuo, Wu, Jing, Nesil, Tanseli, Li, Ming D, Aylor, Kevin W, Liu, Zhenqi

“…Insulin action on hippocampus improves cognitive function, and obesity and type 2 diabetes are associated with decreased cognitive function. Cerebral…”
Get more information

Identification of Diagnostic Markers for Major Depressive Disorder Using Machine Learning Methods by Zhao, Shu, Bao, Zhiwei, Zhao, Xinyi, Xu, Mengxiang, Li, Ming D, Yang, Zhongli

“…Major depressive disorder (MDD) is a global health challenge that impacts the quality of patients' lives severely. The disorder can manifest in many forms with…”
Get full text

Gut Microbiota Changes in Patients with Bipolar Depression by Hu, Shaohua, Li, Ang, Huang, Tingting, Lai, Jianbo, Li, Jingjing, Sublette, M. Elizabeth, Lu, Haifeng, Lu, Qiaoqiao, Du, Yanli, Hu, Zhiying, Ng, Chee H., Zhang, Hua, Lu, Jing, Mou, Tingting, Lu, Shaojia, Wang, Dandan, Duan, Jinfeng, Hu, Jianbo, Huang, Manli, Wei, Ning, Zhou, Weihua, Ruan, Liemin, Li, Ming D., Xu, Yi

“…This study aims to characterize the gut microbiota in depressed patients with bipolar disorder (BD) compared with healthy controls (HCs), to examine the…”
Get full text

A Generalized Combinatorial Approach for Detecting Gene-by-Gene and Gene-by-Environment Interactions with Application to Nicotine Dependence by Lou, Xiang-Yang, Chen, Guo-Bo, Yan, Lei, Ma, Jennie Z., Zhu, Jun, Elston, Robert C., Li, Ming D.

“…The determination of gene-by-gene and gene-by-environment interactions has long been one of the greatest challenges in genetics. The traditional methods are…”
Get full text

CRISPR/Cas9 based gene editing of Frizzled class receptor 6 (FZD6) reveals its role in depressive symptoms through disrupting Wnt/β-catenin signaling pathway by Han, Haijun, Xu, Mengxiang, Wang, Ju, Li, Ming D., Yang, Zhongli

“…[Display omitted] •FZD6 expression was significantly reduced in MDD patients.•Fzd6 knockdown mice presented significant changes in depressive-like…”
Get full text

Insights Into Nicotinic Receptor Signaling in Nicotine Addiction: Implications for Prevention and Treatment by Liu, Wuyi, Li, Ming D

“…Background: Nicotinic acetylcholine receptors (nAChRs) belong to the Cys-loop ligandgated ion-channel (LGIC) superfamily, which also includes the GABA,…”
Get full text

Pharmacological Effects and Regulatory Mechanisms of Tobacco Smoking Effects on Food Intake and Weight Control by Hu, Tongyuan, Yang, Zhongli, Li, Ming D.

“…Beyond promoting smoking initiation and preventing smokers from quitting, nicotine can reduce food intake and body weight and thus is viewed as desirable by…”
Get full text

Correlation Between Prognostic Biomarker SLC1A5 and Immune Infiltrates in Various Types of Cancers Including Hepatocellular Carcinoma by Zhao, Junsheng, Yang, Zhongli, Tu, Mingmin, Meng, Wei, Gao, Hainv, Li, Ming D., Li, Lanjuan

“…Background Solute carrier family 1 member 5 ( SLC1A5 ) is a major glutamine transporter and plays a key role in tumor growth. The main objectives of this study…”
Get full text

Author Correction: CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies by Hu, Yongxian, Li, Jingjing, Ni, Fang, Yang, Zhongli, Gui, Xiaohua, Bao, Zhiwei, Zhao, Houli, Wei, Guoqing, Wang, Yiyun, Zhang, Mingming, Hong, Ruimin, Wang, Linqin, Wu, Wenjun, Mohty, Mohamad, Nagler, Arnon, Chang, Alex H., van den Brink, Marcel R. M., Li, Ming D., Huang, He

Get full text

Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain by Yang, Zhongli, Yang, Jiekun, Mao, Ying, Li, Ming D.

“…Although various susceptibility genes have been revealed to influence tobacco smoking, the underlying regulatory mechanisms between genetic variants and…”
Get full text

Nicotine modulates expression of miR-140, which targets the 3′-untranslated region of dynamin 1 gene (Dnm1) by Huang, Weihua, Li, Ming D.

“…Nicotine stimulation regulates expression of a diversity of genes, but the underlying mechanisms are largely unknown. MicroRNAs (miRNAs) are short endogenous…”
Get full text

Implication of Genes for the N-Methyl-d-Aspartate (NMDA) Receptor in Substance Addictions by Chen, Jiali, Ma, Yunlong, Fan, Rongli, Yang, Zhongli, Li, Ming D.

“…Drug dependence is a chronic brain disease with harmful consequences for both individual users and society. Glutamate is a primary excitatory neurotransmitter…”
Get full text

Development of GMDR-GPU for gene-gene interaction analysis and its application to WTCCC GWAS data for type 2 diabetes by Zhu, Zhixiang, Tong, Xiaoran, Zhu, Zhihong, Liang, Meimei, Cui, Wenyan, Su, Kunkai, Li, Ming D, Zhu, Jun

“…Although genome-wide association studies (GWAS) have identified a significant number of single-nucleotide polymorphisms (SNPs) associated with many complex…”
Get full text

Identification and validation of a novel gene ARVCF associated with alcohol dependence among Chinese population by Shi, Xiaoqiang, Wang, Yan, Yang, Zhongli, Yuan, Wenji, Li, Ming D.

“…Alcohol dependence is a heritable disorder, yet its genetic basis and underlying mechanisms remain poorly understood, especially in Chinese population. In this…”
Get full text

Integrative Analysis of Epigenome and Transcriptome Data Reveals Aberrantly Methylated Promoters and Enhancers in Hepatocellular Carcinoma by Huang, Peng, Xu, Mengxiang, Han, Haijun, Zhao, Xinyi, Li, Ming D., Yang, Zhongli

“…DNA methylation is a key transcription regulator, whose aberration was ubiquitous and important in most cancers including hepatocellular carcinoma (HCC)…”
Get full text