Search Results - "Li, Mengtao"
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Gut microbiota promote the inflammatory response in the pathogenesis of systemic lupus erythematosus
Published in Molecular medicine (Cambridge, Mass.) (01-08-2019)“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease whose onset and progression are affected by genetic and environmental factors. The purpose…”
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JAK Inhibitors: Prospects in Connective Tissue Diseases
Published in Clinical reviews in allergy & immunology (01-12-2020)“…The dysregulation of the JAK–STAT pathway is associated with various immune disorders. Four JAK inhibitors have been approved for rheumatoid arthritis (RA),…”
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Systemic Lupus Erythematosus: Targeted Literature Review of the Epidemiology, Current Treatment, and Disease Burden in the Asia Pacific Region
Published in Arthritis care & research (2010) (01-02-2022)“…Objective To understand the epidemiology, current treatment, and disease burden of systemic lupus erythematosus (SLE) in the Asia Pacific (APAC) region…”
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Protein profiling in systemic sclerosis patients with different pulmonary complications using proteomic antibody microarray
Published in Arthritis research & therapy (17-01-2024)“…Pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD) are leading causes of systemic sclerosis (SSc)-related death. In this study, we aimed…”
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The PD-1/PD-L pathway in rheumatic diseases
Published in Journal of the Formosan Medical Association (01-01-2021)“…Autoimmune diseases are diseases in which the body produces an abnormal immune response to self-antigens and damages its own tissues. Programmed death-1 (PD-1)…”
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Identification of potential susceptibility genes in patients with primary Sjögren’s syndrome-associated pulmonary arterial hypertension through whole exome sequencing
Published in Arthritis research & therapy (20-09-2023)“…Abstract Background Pulmonary arterial hypertension (PAH) is a rare complication of primary Sjögren’s syndrome (pSS). Several genes have proven to be…”
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Prognostic profile of systemic sclerosis: analysis of the clinical EUSTAR cohort in China
Published in Arthritis research & therapy (22-10-2018)“…Systemic sclerosis is a disease that has significant clinical heterogeneity. This study aims to determine the causes and risk factors of death in a single…”
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The involvement and possible mechanism of pro-inflammatory tumor necrosis factor alpha (TNF-α) in thoracic ossification of the ligamentum flavum
Published in PloS one (02-06-2017)“…Thoracic ossification of the ligamentum flavum (TOLF) is characterized by ectopic bone formation in the ligamentum flavum and is considered to be a leading…”
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Spatial-temporal change in urban agricultural land use efficiency from the perspective of agricultural multi-functionality: A case study of the Xi’an metropolitan zone
Published in Journal of geographical sciences (01-12-2017)“…The excessive expansion of urbanized areas has resulted in haphazard land utilization, immoderate consumption of superior agricultural land and water…”
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Chinese Registry of rheumatoid arthritis (CREDIT): II. prevalence and risk factors of major comorbidities in Chinese patients with rheumatoid arthritis
Published in Arthritis research & therapy (15-11-2017)“…Rheumatoid arthritis patients are at higher risk of developing comorbidities. The main objective of this study was to evaluate the prevalence of major…”
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LSO-026 Sirolimus versus mycophenolate mofetil for the treatment of lupus nephritis: results from a real-world CSTAR cohort study
Published in Lupus science & medicine (01-07-2023)“…BackgroundThe effectiveness and safety of sirolimus for the treatment of systemic lupus erythematosus (SLE) and lupus nephritis (LN) have been shown in some…”
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Comparative efficacy of traditional non-selective NSAIDs and selective cyclo-oxygenase-2 inhibitors in patients with acute gout: a systematic review and meta-analysis
Published in BMJ open (10-09-2020)“…ObjectiveTo assess the comparative efficacy of traditional non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclo-oxygenase-2 inhibitors in…”
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The prognosis and management of reclassified systemic lupus erythematosus associated pulmonary arterial hypertension according to 2022 ESC/ERS guidelines
Published in Arthritis research & therapy (27-05-2024)“…The 2022 European Society of Cardiology/European Respiratory Society (ESC/ERS) guideline has recently revised the hemodynamic definition of pulmonary arterial…”
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Comparative Efficacy of Secukinumab Versus Tumor Necrosis Factor Inhibitors for the Treatment of Takayasu Arteritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-08-2023)“…Objective Tumor necrosis factor (TNF) alpha and interleukin‐17 (IL‐17) are thought to be involved in the pathogenesis of Takayasu arteritis (TAK), and TNF…”
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Systemic sclerosis and the COVID-19 pandemic: World Scleroderma Foundation preliminary advice for patient management
Published in Annals of the rheumatic diseases (01-06-2020)“…Due to the frequent presence of interstitial lung disease and widespread use of immunosuppressive treatment, systemic sclerosis (SSc) patients may be…”
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Clinical characteristics of hypertrophic cranial pachymeningitis in granulomatosis with polyangiitis: a retrospective single-center study in China
Published in Arthritis research & therapy (02-01-2024)“…Hypertrophic cranial pachymeningitis (HCP) is uncommon but a poorly understood complication of granulomatosis with polyangiitis (GPA). We conducted this…”
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The clinical characteristics of Chinese Takayasu's arteritis patients: a retrospective study of 411 patients over 24 years
Published in Arthritis research & therapy (25-05-2017)“…We aimed to investigate the clinical characteristics of 411 Chinese Takayasu's arteritis (TAK) patients using a retrospective analysis. We retrospectively…”
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The clinical characteristics and outcomes of patients with systemic sclerosis with myocardial involvement
Published in Orphanet journal of rare diseases (14-04-2023)“…Myocardial involvement (MI) is the primary cause of death in patients with systemic sclerosis (SSc). We analyzed patients with SSc and MI to identify their…”
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Bone mineral density and microarchitecture among Chinese patients with rheumatoid arthritis: a cross-sectional study with HRpQCT
Published in Arthritis research & therapy (24-04-2021)“…Patients with rheumatoid arthritis (RA) are at increased risk of fractures. Although their decline in bone mineral density (BMD) is well-established, data…”
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Baseline Characteristics and Risk Factors of Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus Patients
Published in Medicine (Baltimore) (01-03-2016)“…Peking Union Medical College Hospital (PUMCH) has started a single-center right heart catheterization (RHC)-based pulmonary arterial hypertension (PAH) study…”
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