Search Results - "Li, Mark"
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VDAC2 enables BAX to mediate apoptosis and limit tumor development
Published in Nature communications (26-11-2018)“…Intrinsic apoptosis is critical to prevent tumor formation and is engaged by many anti-cancer agents to eliminate tumor cells. BAX and BAK, the two essential…”
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Genome-wide association data classification and SNPs selection using two-stage quality-based Random Forests
Published in BMC genomics (21-01-2015)“…Single-nucleotide polymorphisms (SNPs) selection and identification are the most important tasks in Genome-wide association data analysis. The problem is…”
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Incidental hepatic tissue detected at cholecystectomy is potentially clinically significant
Published in Human Pathology Reports (01-06-2022)“…•Incidental hepatic tissue obtained via cholecystectomy can harbor clinically significant hepatopathology regardless of size.•Hepatic tissue and special stains…”
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A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers
Published in JNCI : Journal of the National Cancer Institute (01-06-2019)“…Abstract Background Liquid biopsy for plasma circulating tumor DNA (ctDNA) next-generation sequencing (NGS) is commercially available and increasingly adopted…”
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BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
Published in Cell reports (Cambridge) (09-04-2019)“…To elicit apoptosis, BAX metamorphoses from an inert cytosolic monomer into homo-oligomers that permeabilize the mitochondrial outer membrane (MOM). A…”
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Linear regression with many controls of limited explanatory power
Published in Quantitative economics (01-05-2021)“…We consider inference about a scalar coefficient in a linear regression model. One previously considered approach to dealing with many controls imposes…”
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Collection of cell-free DNA for genomic analysis of solid tumors in a clinical laboratory setting
Published in PloS one (27-04-2017)“…The breadth of diagnostic procedures that utilize cell free DNA (cfDNA) from human plasma has increased dramatically in recent years. Here, we confirm that…”
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High-Temperature Refining of Metallurgical-Grade Silicon: A Review
Published in JOM (1989) (01-08-2012)“…Among currently known alternatives for renewable energy sources, solar power is generally regarded as having the most potential to satisfy the ever-growing…”
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Gain-of-Function Variomics and Multi-omics Network Biology for Precision Medicine
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Traditionally, disease causal mutations were thought to disrupt gene function. However, it becomes more clear that many deleterious mutations could exhibit a…”
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Removal of Boron and Phosphorus from Silicon Using CaO-SiO2-Na2O-Al2O3 Flux
Published in Metallurgical and materials transactions. B, Process metallurgy and materials processing science (01-02-2014)“…A combination of solvent refining and flux treatment was employed to remove boron and phosphorus from crude silicon to acceptable levels for solar…”
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Muscularis propria detected at colonic biopsy is not a critical value
Published in Pathology, research and practice (01-08-2020)“…•Muscularis propria rarely occupies specimens from colonic biopsies.•Histologic features differentiate muscularis propria from muscularis mucosa.•Muscularis…”
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Massive Submucosal Ganglia in Colonic Inertia
Published in Archives of pathology & laboratory medicine (1976) (01-02-2018)“…- Colonic inertia is a debilitating form of primary chronic constipation with unknown etiology and diagnostic criteria, often requiring pancolectomy. We have…”
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On the Impact of Dissimilarity Measure in k-Modes Clustering Algorithm
Published in IEEE transactions on pattern analysis and machine intelligence (01-03-2007)“…This correspondence describes extensions to the k-modes algorithm for clustering categorical data. By modifying a simple matching dissimilarity measure for…”
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ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
Published in Cell reports (Cambridge) (16-11-2021)“…Brown adipose tissue (BAT) thermogenic activity is tightly regulated by cellular redox status, but the underlying molecular mechanisms are incompletely…”
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Age‐ and sex‐related changes in body weights and clinical pathology analytes in cynomolgus monkeys (Macaca Fascicularis) of Mauritius origin
Published in Veterinary clinical pathology (01-09-2022)“…Background Clinical pathology and body weight information for the cynomolgus monkey in the literature is primarily derived from a small number of animals with…”
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Kinetics of Na2O and B2O3 Loss From CaO-SiO2-Al2O3 Slags
Published in Metallurgical and materials transactions. B, Process metallurgy and materials processing science (01-02-2015)“…The present work was carried out to study the loss of Na 2 O and B 2 O 3 from CaO-SiO 2 -Al 2 O 3 slags containing high content of Al 2 O 3 and Na 2 O in the…”
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Phenotypic and genotypic differences in colorectal carcinoma among Caucasians, Asians, and Hispanics lack statistical significance
Published in Pathology, research and practice (01-05-2018)“…Colorectal carcinoma (CRC) has been shown to have both genetic and environmental factors that can promote carcinoma development. Previous studies have found…”
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The Nokia Lumia 1020 smartphone as a 41-megapixel photomicroscope
Published in Histopathology (01-06-2014)Get full text
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A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells
Published in Molecular therapy. Nucleic acids (03-12-2021)“…Micropeptides (microproteins) encoded by transcripts previously annotated as long noncoding RNAs (lncRNAs) are emerging as important mediators of fundamental…”
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