Search Results - "Li, Luowei"

Screening compounds with a novel high-throughput ABCB1-mediated efflux assay identifies drugs with known therapeutic targets at risk for multidrug resistance interference by Ansbro, Megan R, Shukla, Suneet, Ambudkar, Suresh V, Yuspa, Stuart H, Li, Luowei

“…ABCB1, also known as P-glycoprotein (P-gp) or multidrug resistance protein 1 (MDR1), is a membrane-associated multidrug transporter of the ATP-binding cassette…”
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The Skin Cancer Chemotherapeutic Agent Ingenol-3-Angelate (PEP005) Is a Substrate for the Epidermal Multidrug Transporter (ABCB1) and Targets Tumor Vasculature by LUOWEI LI, SHUKLA, Suneet, LEE, Andrew, GARFIELD, Susan H, MALONEY, David J, AMBUDKAR, Suresh V, YUSPA, Stuart H

“…Ingenol-3-angelate (Ing3A), extracted from Euphorbia peplus, is currently in clinical trials for eradicating basal cell carcinoma, actinic keratosis, and…”
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Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation by Malik, Mariam, Jividen, Kasey, Padmakumar, V. C, Cataisson, Christophe, Li, Luowei, Lee, Jessica, Howard, O. M. Zack, Yuspa, Stuart H

“…Nuclear translocation of cytosolic CLIC4 is an essential feature of its proapoptotic and prodifferentiation functions. Here we demonstrate that CLIC4 is…”
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Protein Kinase C Negatively Regulates Akt Activity and Modifies UVC-induced Apoptosis in Mouse Keratinocytes by Li, Luowei, Sampat, Keeran, Hu, Nancy, Zakari, Julia, Yuspa, Stuart H.

“…Skin keratinocytes are subject to frequent chemical and physical injury and have developed elaborate cell survival mechanisms to compensate. Among these, the…”
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RasGRP3 Contributes to Formation and Maintenance of the Prostate Cancer Phenotype by DAZHI YANG, KEDEI, Noemi, YUSPA, Stuart H, BLUMBERG, Peter M, LUOWEI LI, JUAN TAO, VELASQUEZ, Julia F, MICHALOWSKI, Aleksandra M, TOTH, Balázs I, MARINCSAK, Rita, VARGA, Attila, BIRO, Tamás

“…RasGRP3 mediates the activation of the Ras signaling pathway that is present in many human cancers. Here, we explored the involvement of RasGRP3 in the…”
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Protein Kinase Cδ Targets Mitochondria, Alters Mitochondrial Membrane Potential, and Induces Apoptosis in Normal and Neoplastic Keratinocytes When Overexpressed by an Adenoviral Vector by Li, Luowei, Lorenzo, Patricia S., Bogi, Krisztina, Blumberg, Peter M., Yuspa, Stuart H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CLIC4 mediates and is required for Ca²⁺-induced keratinocyte differentiation by Suh, Kwang S, Mutoh, Michihiro, Mutoh, Tomoko, Li, Luowei, Ryscavage, Andrew, Crutchley, John M, Dumont, Rebecca A, Cheng, Christina, Yuspa, Stuart H

“…Keratinocyte differentiation requires integrating signaling among intracellular ionic changes, kinase cascades, sequential gene expression, cell cycle arrest,…”
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Direct quantification of polo-like kinase 1 activity in cells and tissues using a highly sensitive and specific ELISA assay by Park, Jung-Eun, Li, Luowei, Park, Joobae, Knecht, Rainald, Strebhardt, Klaus, Yuspa, Stuart H, Lee, Kyung S

“…Polo-like kinase 1 (Plk1) plays a pivotal role in the regulation of cellular proliferation. Plk1 is overexpressed in [almost equal to]80% of human tumors of…”
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Protein kinase Cδ-mediated phosphorylation of α6β4 is associated with reduced integrin localization to the hemidesmosome and decreased keratinocyte attachment by ALT, Addy, OHBA, Motoi, LUOWEI LI, GARTSBEIN, Marina, BELANGER, Adam, DENNING, Mitchell F, KUROKI, Toshio, YUSPA, Stuart H, TENNENBAUM, Tamar

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Computational study of nitrogen-doped vanadium disulfide-loaded single-atom catalysts for the electrocatalytic reduction of CO2 by Zhang, Canyu, Yang, Kuo, Li, Luowei, Liu, Wenju, Yang, Ziqian, Cao, Qiue, Li, Wei, Liu, Shixi

“…The diagram vividly depicts the reduction of CO2 to CH4 on the active sites of TM@N3-VS2. [Display omitted] •The novel SACs (TM@N3-VS2) were designed based on…”
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Effect of a tyrosine 155 to phenylalanine mutation of protein kinase Cδ on the proliferative and tumorigenic properties of NIH 3T3 fibroblasts by Ács, Péter, Beheshti, Maryam, Szállási, Zoltán, Li, Luowei, Yuspa, Stuart H., Blumberg, Peter M.

“…Tyrosine phosphorylation has emerged as an important mechanism in the regulation of enzyme function. In this paper, we describe a mutant of PKCδ altered at a…”
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The oxidoreductase CLIC4 is required to maintain mitochondrial function and resistance to exogenous oxidants in breast cancer cells by Al Khamici, Heba, Sanchez, Vanesa C., Yan, Hualong, Cataisson, Christophe, Michalowski, Aleksandra M., Yang, Howard H., Li, Luowei, Lee, Maxwell P., Huang, Jing, Yuspa, Stuart H.

“…The chloride intracellular channel-4 (CLIC4) is one of the six highly conserved proteins in the CLIC family that share high structural homology with GST-omega…”
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Topical Application of a Dual ABC Transporter Substrate and NF-κB Inhibitor Blocks Multiple Sources of Cutaneous Inflammation in Mouse Skin by Li, Luowei, Cataisson, Christophe, Flowers, Brittany, Fraser, Elise, Sanchez, Vanesa, Day, Chi-Ping, Yuspa, Stuart H.

“…Among the molecular signals underlying cutaneous inflammation is the transcription complex NF-κB, its upstream modulators, and cytokines and chemokines that…”
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Molecular basis of Mitomycin C enhanced corneal sensory nerve repair after debridement wounding by Stepp, Mary Ann, Pal-Ghosh, Sonali, Tadvalkar, Gauri, Li, Luowei, Brooks, Stephen R., Morasso, Maria I.

“…The ocular surface is covered by stratified squamous corneal epithelial cells that are in cell:cell contact with the axonal membranes of a dense collection of…”
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Mouse epidermal keratinocyte culture by Li, Luowei

“…Cultured mouse epidermal keratinocytes provide a powerful model for studying epidermal proliferation, differentiation, pathogenesis, and oncogenic…”
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RAS oncogene signal strength regulates matrisomal gene expression and tumorigenicity of mouse keratinocytes by Cataisson, Christophe, Lee, Alex J, Zhang, Ashley M, Mizes, Alicia, Korkmaz, Serena, Carofino, Brandi L, Meyer, Thomas J, Michalowski, Aleksandra M, Li, Luowei, Yuspa, Stuart H

“…Environmental and molecular carcinogenesis are linked by the discovery that chemical carcinogen induced-mutations in the Hras or Kras genes drives tumor…”
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Cover Image, Volume 60, Issue 12 by Lee, Alex J., Fraser, Elise, Flowers, Brittany, Kim, Jee, Wong, Kenneth, Cataisson, Christophe, Liu, Huaitian, Yang, Howard, Lee, Maxwell P., Yuspa, Stuart H., Li, Luowei

“…The cover image is based on the Research Article RAS induced senescence of skin keratinocytes is mediated through Rho‐associated protein kinase (ROCK) by Alex…”
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Controlled synthesis of Bi2S3/g-C3N4 nanosheets for efficient degradation of rhodamine B and reduction of Cr (VI) under visible light by Yang, Kuo, Yang, Yun, Jiang, Yifan, Ye, Bingjie, Li, Luowei, Liu, Wenju, Yan, Tong, Li, Wei, Liu, Shixi

“…In this study, a flower-shaped Bi2S3/g-C3N4 heterostructure was synthesized via a hydrothermal method and utilized as a visible-light-driven photocatalyst for…”
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RAS induced senescence of skin keratinocytes is mediated through Rho‐associated protein kinase (ROCK) by Lee, Alex J., Fraser, Elise, Flowers, Brittany, Kim, Jee, Wong, Kenneth, Cataisson, Christophe, Liu, Huaitian, Yang, Howard, Lee, Maxwell P., Yuspa, Stuart H., Li, Luowei

“…Cellular senescence is a well‐documented response to oncogene activation in many tissues. Multiple pathways are invoked to achieve senescence indicating its…”
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T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis by Cataisson, Christophe, Salcedo, Rosalba, Michalowski, Aleksandra M, Klosterman, Mary, Naik, Shruti, Li, Luowei, Pan, Michelle J, Sweet, Amalia, Chen, Jin-Qiu, Kostecka, Laurie G, Karwan, Megan, Smith, Loretta, Dai, Ren-Ming, Stewart, C Andrew, Lyakh, Lyudmila, Hsieh, Wang-Ting, Khan, Asra, Yang, Howard, Lee, Maxwell, Trinchieri, Giorgio, Yuspa, Stuart H

“…Cancer development requires a favorable tissue microenvironment. By deleting in keratinocytes or specific bone marrow subpopulations in oncogenic RAS-mediated…”
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