Search Results - "Li, Lucy X"
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Unraveling synthesis of the cryptococcal cell wall and capsule
Published in Glycobiology (Oxford) (01-10-2018)“…Fungal pathogens cause devastating infections in millions of individuals each year, representing a huge but underappreciated burden on human health. One of…”
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5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus
Published in Nature communications (08-01-2020)“…Patients infected with the fungal pathogen Cryptococcus are most effectively treated with a combination of 5-fluorocytosine (5FC) and amphotericin B. 5FC acts…”
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3
The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18
Published in PLoS pathogens (01-11-2012)“…Secretory polymorphic serine/threonine kinases control pathogenesis of Toxoplasma gondii in the mouse. Genetic studies show that the pseudokinase ROP5 is…”
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4
Peeling the onion: the outer layers of Cryptococcus neoformans
Published in Memórias do Instituto Oswaldo Cruz (2018)“…Cryptococcus neoformans is an opportunistic fungal pathogen that is ubiquitous in the environment. It causes a deadly meningitis that is responsible for over…”
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Candidemia Following Severe COVID‐19 in Hospitalised and Critical Ill Patients: A Systematic Review and Meta‐Analysis
Published in Mycoses (01-10-2024)“…ABSTRACT Rationale The epidemiology and clinical impact of COVID‐19‐associated candidemia (CAC) remained uncertain, leaving gaps in understanding its…”
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6
Xylose donor transport is critical for fungal virulence
Published in PLoS pathogens (18-01-2018)“…Cryptococcus neoformans, an AIDS-defining opportunistic pathogen, is the leading cause of fungal meningitis worldwide and is responsible for hundreds of…”
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7
Closing the Gaps in Hepatitis C Knowledge Among Internal Medicine Residents in the United States
Published in American journal of medicine open (01-12-2024)“…HCV knowledge remains limited among IM residents despite expansion of treatment options.Baseline HCV knowledge was not greater among more senior trainees,…”
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8
Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response
Published in mBio (19-04-2016)“…Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over 600,000 people annually. Here, we report integrated computational and…”
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9
Catalytic and non-catalytic roles for the mono-ADP-ribosyltransferase Arr in the mycobacterial DNA damage response
Published in PloS one (18-07-2011)“…Recent evidence indicates that the mycobacterial response to DNA double strand breaks (DSBs) differs substantially from previously characterized bacteria…”
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10
The Capsid Protein Encoded by UL17 of Herpes Simplex Virus 1 Interacts with Tegument Protein VP13/14
Published in Journal of Virology (01-08-2010)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
Plasmodium IspD (2-C-Methyl‑d‑erythritol 4‑Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target
Published in ACS infectious diseases (10-04-2015)“…As resistance to current therapies spreads, novel antimalarials are urgently needed. In this work, we examine the potential for therapeutic intervention via…”
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12
Incidence and characteristics of needlestick injuries among medical trainees at a community teaching hospital : A cross-sectional study
Published in Journal of Occupational Health (01-01-2017)“…[Abstract] : [Objectives] : This field study aimed to determine the incidence and distribution of needlestick injuries among medical trainees at a community…”
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13
Antibiotic stewardship in direct-to-consumer telemedicine: translating interventions into the virtual realm
Published in Journal of antimicrobial chemotherapy (24-12-2021)“…Direct-to-consumer (DTC) telemedicine is an increasingly popular modality for delivery of medical care via a virtual platform. As most DTC telemedicine visits…”
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Knowledge of Pre- and Postexposure Prophylaxis for HIV Prevention Among Internal Medicine Residents in the United States
Published in AIDS education and prevention (01-02-2024)“…Prescription rates of pre-exposure prophylaxis (PrEP) have remained low among noninfectious disease providers in the United States despite almost a decade…”
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15
Cryptococcus neoformans Evades Pulmonary Immunity by Modulating Xylose Precursor Transport
Published in Infection and immunity (21-07-2020)“…is a fungal pathogen that kills almost 200,000 people each year and is distinguished by abundant and unique surface glycan structures that are rich in xylose…”
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16
Progressive disseminated histoplasmosis: The experience in one non-endemic medical center
Published in Medical mycology (Oxford) (01-12-2023)“…Histoplasmosis, the most common endemic mycosis in North America, presents in a myriad of ways, spanning the spectrum from self-limiting pneumonia to…”
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UDP-Glucuronic Acid Transport Is Required for Virulence of Cryptococcus neoformans
Published in mBio (30-01-2018)“…Glycans play diverse biological roles, ranging from structural and regulatory functions to mediating cellular interactions. For pathogens, they are also often…”
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Cryptococcus neoformans UGT1 encodes a UDP-Galactose/UDP-GalNAc transporter
Published in Glycobiology (Oxford) (01-01-2017)“…Cryptococcus neoformans, an opportunistic fungal pathogen, produces a glycan capsule to evade the immune system during infection. This definitive virulence…”
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The capsid protein encoded by U(L)17 of herpes simplex virus 1 interacts with tegument protein VP13/14
Published in Journal of virology (01-08-2010)“…The U(L)17 protein (pU(L)17) of herpes simplex virus 1 (HSV-1) likely associates with the surfaces of DNA-containing capsids in a heterodimer with pU(L)25…”
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Severe Monkeypox in Hospitalized Patients - United States, August 10-October 10, 2022
Published in MMWR. Morbidity and mortality weekly report (04-11-2022)“…As of October 21, 2022, a total of 27,884 monkeypox cases (confirmed and probable) have been reported in the United States. Gay, bisexual, and other men who…”
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