Search Results - "Li, Lian"
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Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism
Published in Science (American Association for the Advancement of Science) (05-02-2016)“…It is thought that KRAS oncoproteins are constitutively active because their guanosine triphosphatase (GTPase) activity is disabled. Consequently, drugs…”
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2
Generalized Jacobi functions and their applications to fractional differential equations
Published in Mathematics of computation (01-07-2016)“…In this paper, we consider spectral approximation of fractional differential equations (FDEs). A main ingredient of our approach is to define a new class of…”
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3
Targeting Autophagy for the Treatment of Alzheimer's Disease: Challenges and Opportunities
Published in Frontiers in molecular neuroscience (22-08-2019)“…Alzheimer's disease (AD) is the most common type of dementia which characterized by a progressive loss of memory and cognitive function due to degeneration of…”
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4
Information entropy of coding metasurface
Published in Light, science & applications (01-11-2016)“…Because of their exceptional capability to tailor the effective medium parameters, metamaterials have been widely used to control electromagnetic waves, which…”
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5
Berberine exerts a protective effect on rats with polycystic ovary syndrome by inhibiting the inflammatory response and cell apoptosis
Published in Reproductive biology and endocrinology (07-01-2021)“…Polycystic ovary syndrome (PCOS) is a common endocrine disease of the female reproductive system that seriously affects women's health. Berberine (BBR) has…”
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6
Two cases of spontaneous rupture of the uterine artery in the perinatal period: A case report
Published in Medicine (Baltimore) (19-05-2023)“…Uterine artery spontaneous rupture is a rare but potentially life-threatening complication during pregnancy and puerperium. The lack of typical symptoms makes…”
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Maximize Microbiome Research in Neurotrauma and Other Fields: A Proposal to Require Microbiome Abundance Data Accessibility for Publication: Response to You W et al., Traumatic Brain Injury Induces Gastrointestinal Dysfunction and Dysbiosis of Gut Microbiota Accompanied by Alterations of Bile Acid Profile (DOI: 10.1089/neu.2020.7526)
Published in Journal of neurotrauma (01-01-2024)Get more information
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8
Sleep duration and obesity in children: A systematic review and meta‐analysis of prospective cohort studies
Published in Journal of paediatrics and child health (01-04-2017)“…Aim Childhood obesity is a major public problem worldwide, and sleep duration may be associated with childhood obesity. We conducted a systematic review and…”
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9
A new framework for solving fractional optimal control problems using fractional pseudospectral methods
Published in Automatica (Oxford) (01-04-2017)“…The main purpose of this work is to provide new fractional pseudospectral methods for solving fractional optimal control problems (FOCPs). We develop…”
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10
Genome-wide profiling in colorectal cancer identifies PHF19 and TBC1D16 as oncogenic super enhancers
Published in Nature communications (04-11-2021)“…Colorectal cancer is one of the most common cancers in the world. Although genomic mutations and single nucleotide polymorphisms have been extensively studied,…”
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11
Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer
Published in Science translational medicine (18-09-2019)“…KRAS represents an excellent therapeutic target in lung cancer, the most commonly mutated form of which can now be blocked using KRAS-G12C mutant-specific…”
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12
Adsorption of Cadmium Ions from an Aqueous Solution on a Highly Stable Dopamine-Modified Magnetic Nano-Adsorbent
Published in Nanoscale research letters (28-11-2019)“…Magnetic nanomaterials were functionalized with dopamine hydrochloride as the functional reagent to afford a core–shell-type Fe 3 O 4 modified with…”
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13
Harnessing nanomedicine to overcome the immunosuppressive tumor microenvironment
Published in Acta pharmacologica Sinica (01-07-2020)“…Cancer immunotherapy has received extensive attention due to its ability to activate the innate or adaptive immune systems of patients to combat tumors…”
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14
Production Task Queue Optimization Based on Multi-Attribute Evaluation for Complex Product Assembly Workshop
Published in PloS one (28-09-2015)“…The production task queue has a great significance for manufacturing resource allocation and scheduling decision. Man-made qualitative queue optimization…”
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15
An Efficient Spectral Trust-Region Deflation Method for Multiple Solutions
Published in Journal of scientific computing (01-04-2023)“…It is quite common that a nonlinear partial differential equation (PDE) admits multiple distinct solutions and each solution may carry a unique physical…”
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16
Optimal parameters selection for BP neural network based on particle swarm optimization: A case study of wind speed forecasting
Published in Knowledge-based systems (01-01-2014)“…As a clean and renewable energy source, wind energy has been increasingly gaining global attention. Wind speed forecast is of great significance for wind…”
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17
Pathologic myopia: advances in imaging and the potential role of artificial intelligence
Published in British journal of ophthalmology (01-05-2023)“…Pathologic myopia is a severe form of myopia that can lead to permanent visual impairment. The recent global increase in the prevalence of myopia has been…”
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18
Expression patterns of programmed death ligand 1 correlate with different microenvironments and patient prognosis in hepatocellular carcinoma
Published in British journal of cancer (03-07-2018)“…Background Recent clinical studies have suggested that programmed death ligand 1 (PD-L1) expression in a tumour could be a potential biomarker for PD-L1/PD-1…”
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19
Extreme Multistability in a Hopfield Neural Network Based on Two Biological Neuronal Systems
Published in IEEE transactions on circuits and systems. II, Express briefs (01-11-2022)“…Based on different biological neuronal systems, various memristive neuron and neuron network models are generated. In this brief, a three-neurons-based…”
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Liver kinase B1/AMP‐activated protein kinase‐mediated regulation by gentiopicroside ameliorates P2X7 receptor‐dependent alcoholic hepatosteatosis
Published in British journal of pharmacology (01-05-2018)“…Background and Purpose Regulating P2X7 receptor‐mediated activation of NLRP3 inflammasomes could be a therapeutic strategy to treat alcoholic hepatosteatosis…”
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