Search Results - "Li, Li"
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1
Efficacy, Safety, and Immunogenicity of an Escherichia coli-Produced Bivalent Human Papillomavirus Vaccine: An Interim Analysis of a Randomized Clinical Trial
Published in JNCI : Journal of the National Cancer Institute (01-02-2020)“…Abstract Background The high cost and insufficient supply of human papillomavirus (HPV) vaccines have slowed the pace of controlling cervical cancer. A phase…”
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2
Blocking ATM-dependent NF-κB pathway overcomes niche protection and improves chemotherapy response in acute lymphoblastic leukemia
Published in Leukemia (01-10-2019)“…Bone marrow (BM) niche responds to chemotherapy-induced cytokines secreted from acute lymphoblastic leukemia (ALL) cells and protects the residual cells from…”
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3
The effect of Clostridium butyricum on symptoms and fecal microbiota in diarrhea-dominant irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial
Published in Scientific reports (14-02-2018)“…Irritable bowel syndrome (IBS) is a common disorder in gastrointestinal system and impairs the quality of life of the patients. Clostridium butyricum ( CB ) is…”
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4
Rhythmic cilia changes support SCN neuron coherence in circadian clock
Published in Science (American Association for the Advancement of Science) (02-06-2023)“…The suprachiasmatic nucleus (SCN) drives circadian clock coherence through intercellular coupling, which is resistant to environmental perturbations. We report…”
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5
Two-billion-year-old volcanism on the Moon from Chang’e-5 basalts
Published in Nature (London) (02-12-2021)“…The Moon has a magmatic and thermal history that is distinct from that of the terrestrial planets 1 . Radioisotope dating of lunar samples suggests that most…”
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6
Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study
Published in Chinese medical journal (05-05-2020)“…Human infections with zoonotic coronaviruses (CoVs), including severe acute respiratory syndrome (SARS)-CoV and Middle East respiratory syndrome (MERS)-CoV,…”
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7
A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
Published in Journal of hematology and oncology (20-12-2018)“…Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M,…”
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8
Chronic colitis exacerbates NLRP3-dependent neuroinflammation and cognitive impairment in middle-aged brain
Published in Journal of neuroinflammation (06-07-2021)“…Neuroinflammation is a major driver of age-related brain degeneration and concomitant functional impairment. In patients with Alzheimer's disease, the most…”
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Effect of Remote Ischemic Conditioning vs Usual Care on Neurologic Function in Patients With Acute Moderate Ischemic Stroke: The RICAMIS Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (16-08-2022)“…Preclinical and clinical studies have suggested a neuroprotective effect of remote ischemic conditioning (RIC), which involves repeated occlusion/release…”
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10
Anti-diabetic Role of Adropin in Streptozotocin Induced Diabetic Rats via Alteration of PI3K/Akt and Insulin Signaling Pathway
Published in Journal of Oleo Science (01-01-2021)“…Diabetes mellitus (DM) is a hyperglycemia-related multifactorial condition with an elevated risk of microvascular and microvascular complications associated…”
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11
X-ray-activated long persistent phosphors featuring strong UVC afterglow emissions
Published in Light, science & applications (14-11-2018)“…Phosphors emitting visible and near-infrared persistent luminescence have been explored extensively owing to their unusual properties and commercial interest…”
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12
Traditional Herbal Medicine: A Potential Therapeutic Approach for Adjuvant Treatment of Non-small Cell Lung Cancer in the Future
Published in Integrative Cancer Therapies (01-01-2022)“…Lung carcinoma is the primary reason for cancer-associated mortality, and it exhibits the highest mortality and incidence in developed and developing…”
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13
PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer
Published in Cell death & disease (03-07-2018)“…Chemotherapy represents an important treatment option for colorectal cancer (CRC), but only half of the patients benefit from these regimens. We explored the…”
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14
The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
Published in The Journal of clinical investigation (01-12-2009)“…The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is dysregulated in various cancers, and its upregulation strongly correlates…”
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15
Host selection shapes crop microbiome assembly and network complexity
Published in The New phytologist (01-01-2021)“…Summary Plant microbiomes are essential to host health and productivity but the ecological processes that govern crop microbiome assembly are not fully known…”
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16
A direct comparison of four high‐risk human papillomavirus tests versus the cobas test: Detecting CIN2+ in low‐resource settings
Published in Journal of medical virology (01-07-2019)“…Low‐cost, accurate high‐risk human papillomavirus (HR‐HPV) tests are needed for cervical cancer screening in limited‐resource settings. More than 200 cervical…”
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17
LncRNA WTAPP1 Promotes Migration and Angiogenesis of Endothelial Progenitor Cells via MMP1 Through MicroRNA 3120 and Akt/PI3K/Autophagy Pathways
Published in Stem cells (Dayton, Ohio) (01-12-2018)“…Efficient recruitment and angiogenesis of endothelial progenitor cells (EPCs) are critical during a thrombus event. However, the details of EPC recruitment and…”
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18
GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway
Published in Journal of experimental & clinical cancer research (22-05-2019)“…Gastric cancer is one of the deadliest malignant tumours, with a high incidence in China, and is regulated by aberrantly overexpressed oncogenes. However,…”
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MiR‐205 promotes endothelial progenitor cell angiogenesis and deep vein thrombosis recanalization and resolution by targeting PTEN to regulate Akt/autophagy pathway and MMP2 expression
Published in Journal of cellular and molecular medicine (01-12-2019)“…MicroRNAs (MiRNAs, MiRs) represent a class of conserved small non‐coding RNAs that affect post‐transcriptional gene regulation and play a vital role in…”
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20
Low dose decitabine treatment induces CD80 expression in cancer cells and stimulates tumor specific cytotoxic T lymphocyte responses
Published in PloS one (09-05-2013)“…Lack of immunogenicity of cancer cells has been considered a major reason for their failure in induction of a tumor specific T cell response. In this paper, we…”
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