Search Results - "Li, Jianru"
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Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson’s disease
Published in Nature communications (08-12-2023)“…Nanomedicine-based anti-neuroinflammation strategy has become a promising dawn of Parkinson’s disease (PD) treatment. However, there are significant gaps in…”
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Climatic and tectonic controls on chemical weathering in tropical Southeast Asia (Malay Peninsula, Borneo, and Sumatra)
Published in Chemical geology (06-01-2012)“…Clay mineralogy and major-element geochemistry were investigated on 58 surface sediment samples collected in 27 rivers draining Malay Peninsula, Borneo, and…”
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Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage
Published in Journal of neuroinflammation (25-05-2020)“…Neuroinflammation is closely associated with the poor prognosis in subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of…”
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Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
Published in Scientific reports (25-05-2017)“…The NLRP3 inflammasome is activated in the early period following subarachnoid hemorrhage(SAH), resulting in inflammatory responses. Recent studies have shown…”
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Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage
Published in Journal of pineal research (01-01-2014)“…Melatonin is a strong antioxidant that has beneficial effects against early brain injury (EBI) following a subarachnoid hemorrhage (SAH) in rats; protection…”
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Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice
Published in Frontiers in microbiology (06-05-2021)“…Intracerebral hemorrhage (ICH) induces a strong hematoma-related neuroinflammatory reaction and alters peripheral immune homeostasis. Recent research has found…”
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In situ observation of contour currents in the northern South China Sea: Applications for deepwater sediment transport
Published in Earth and planetary science letters (15-11-2015)“…Deepwater currents and related suspended sediment concentration were obtained by an Acoustic Doppler Current Profiler (ADCP) mooring system in the northern…”
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Electrodeposition of neodymium from betaine-ethylene glycol deep eutectic solvent using neodymium oxide as a precursor
Published in Electrochemistry communications (01-12-2023)“…The electrodeposition of neodymium was investigated in betaine-ethylene glycol (Bet-EG) deep eutectic solvent (DES) containing neodymium oxide (Nd2O3) at…”
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Melatonin attenuates inflammatory response-induced brain edema in early brain injury following a subarachnoid hemorrhage: a possible role for the regulation of pro-inflammatory cytokines
Published in Journal of pineal research (01-10-2014)“…Melatonin is a strong anti‐oxidant that has beneficial effects against early brain injury (EBI) following a subarachnoid hemorrhage (SAH) in rats; protection…”
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S100A4 enhances protumor macrophage polarization by control of PPAR-γ-dependent induction of fatty acid oxidation
Published in Journal for immunotherapy of cancer (01-06-2021)“…BackgroundThe peroxisome proliferator-activated receptor γ (PPAR-γ)-dependent upregulation of fatty acid oxidation (FAO) mediates protumor (also known as…”
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Design, synthesis, structure-activity relationships and mechanism of action of new quinoline derivatives as potential antitumor agents
Published in European journal of medicinal chemistry (15-01-2019)“…A series of new quinoline derivatives was designed, synthesized and evaluated as potential antitumor agents. The results indicated that most compounds…”
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The Polarization States of Microglia in TBI: A New Paradigm for Pharmacological Intervention
Published in Neural plasticity (01-01-2017)“…Traumatic brain injury (TBI) is a serious medical and social problem worldwide. Because of the complex pathophysiological mechanisms of TBI, effective…”
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Long eccentricity cycle in Pliocene oceanic carbon reservoir: A comparison between the Mediterranean and the South China Sea
Published in Deep-sea research. Part II, Topical studies in oceanography (01-12-2015)“…As quantitative paleoclimate time series extend deeper into the geological past, growing evidence indicates the extensive occurrence of the 400-kyr long…”
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Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes
Published in Journal of neuroinflammation (23-08-2021)“…White matter injury (WMI) is a major neuropathological event associated with intracerebral hemorrhage (ICH). P2X purinoreceptor 4 (P2X4R) is a member of the…”
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Synthesis and structure–activity relationships of harmine derivatives as potential antitumor agents
Published in European journal of medicinal chemistry (01-02-2013)“…Harmine, a naturally occurring β-carboline alkaloid, showed good antitumor activities together with remarkable neurotoxic effects in animal models. In order to…”
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The Preferred Locations of Meningioma According to Different Biological Characteristics Based on Voxel-Wise Analysis
Published in Frontiers in oncology (21-08-2020)“…Objective: Meningiomas presented preferred intracranial distribution, which may reflect potential biological natures. This study aimed to analyze the preferred…”
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White Matter Injury After Intracerebral Hemorrhage
Published in Frontiers in neurology (10-06-2021)“…Spontaneous intracerebral hemorrhage (ICH) accounts for 15% of all stroke cases. ICH is a devastating form of stroke associated with high morbidity, mortality,…”
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AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury
Published in Journal of neuroinflammation (07-07-2021)“…Complex changes in the brain microenvironment following traumatic brain injury (TBI) can cause neurological impairments for which there are few efficacious…”
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Underwater Image High Definition Display Using the Multilayer Perceptron and Color Feature-Based SRCNN
Published in IEEE access (2019)“…High-definition display technology for underwater images is of great significance for many applications, such as marine animal observation, seabed mining, and…”
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