Search Results - "Li, Jianheng"
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New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol
Published in Organic & biomolecular chemistry (21-08-2014)“…Alzheimer's disease (AD) is currently one of the most difficult and challenging diseases to treat. Based on the ‘multi-target-directed ligands’ (MTDLs)…”
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Isoalantolactone protects against ethanol-induced gastric ulcer via alleviating inflammation through regulation of PI3K-Akt signaling pathway and Th17 cell differentiation
Published in Biomedicine & pharmacotherapy (01-04-2023)“…Gastric ulcer (GU) is one of the most prevalent digestive system diseases in humans, and it has been linked to inflammation. Previous studies have demonstrated…”
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Height detection of crop divider toes of sugarcane harvester based on Kalman adaptive adjustment
Published in Scientific reports (05-10-2023)“…Crop divider toes are an essential device of sugarcane harvester. Moving forward against the ground is a critical way to improve the harvesting rate of lodged…”
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Synthesis and biological evaluation of a new series of ebselen derivatives as glutathione peroxidase (GPx) mimics and cholinesterase inhibitors against Alzheimer’s disease
Published in Bioorganic & medicinal chemistry (15-02-2014)“…A series of ebselen derivatives were designed, synthesised and evaluated as inhibitors of cholinesterases (ChEs) and glutathione peroxidase (GPx) mimics. Most…”
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Application of improved YOLOv7-based sugarcane stem node recognition algorithm in complex environments
Published in Frontiers in plant science (23-08-2023)“…Introduction Sugarcane stem node detection is one of the key functions of a small intelligent sugarcane harvesting robot, but the accuracy of sugarcane stem…”
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Prescription opioid dispensing patterns among patients with schizophrenia or bipolar disorder
Published in BMC psychiatry (02-04-2024)“…Patients with schizophrenia (SZ) or bipolar disorder (BD) may have increased risk of complications from prescribed opioids, including opioid-induced…”
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Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos
Published in Frontiers in pharmacology (21-04-2021)“…Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from plants, is widely used in traditional herbal medicine to treat various diseases…”
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Synthesis of the Anti-Prostate Cancer Drug Abiraterone Acetate
Published in Heterocycles (2018)Get full text
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A pseudo‐colour enhancement algorithm for high‐bit RAW greyscale image of X‐ray film displaying on low‐bit monitors
Published in IET image processing (01-02-2023)“…X‐ray flaw detection is widely used in non‐destructive area. The intuitive defect information can be obtained through the X‐ray film, which is usually…”
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The protective effects of mangiferin on metabolic and organs functions in the adolescent rat model of alcohol abuse
Published in Journal of functional foods (01-07-2018)“…[Display omitted] •MG can up-regulate the expression level of GFAP in brain.•MG can up-regulate the expression levels of IRS-2 in testes and GDF-9 in…”
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Multi-objective ant lion optimization for parameter optimization of wireless power transfer systems
Published in AIP advances (01-11-2023)“…The effective transmission distance of a magnetic coupling resonance (MCR) wireless power transfer (WPT) system is an essential index of wireless power…”
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12
Nanotechnology boosts the efficiency of tumor diagnosis and therapy
Published in Frontiers in bioengineering and biotechnology (28-07-2023)“…The incidence and mortality of cancer are gradually increasing. The highly invasive and metastasis of tumor cells increase the difficulty of diagnosis and…”
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13
Photonic Crystal Waveguide Electro-Optic Modulator With a Wide Bandwidth
Published in Journal of lightwave technology (15-05-2013)“…Future optical systems will require electro-optic (EO) modulators with bandwidths of 100 GHz. For high-speed modulation, a photonic crystal (PhC) waveguide…”
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Metabolic Changes After a 24-Week Soccer-Based Adaptation of the Diabetes Prevention Program in Hispanic Males: A One-Arm Pilot Clinical Trial
Published in Frontiers in sports and active living (12-11-2021)“…One third of the U.S. adult population is estimated to have obesity-associated prediabetes. Hispanics have a 50% higher type 2 diabetes death rate compared to…”
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Epidemiology of PCBs and neurodevelopment: Systematic assessment of multiplicity and completeness of reporting
Published in Global Epidemiology (01-11-2020)“…Assessments of scientific evidence often involve a systematic comparison of findings within and across studies. An important consideration in systematic…”
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Determination of A-site deficiency in lanthanum manganite by XRD intensity ratio
Published in Journal of solid state chemistry (01-04-2008)“…A method based on the X-ray diffraction intensity ratio was developed to determine the maximum deficiency that the perovskite-structured La 1− x MnO 3± δ can…”
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Treatment of Neurodegenerative Diseases with Bioactive Components of Tripterygium wilfordii
Published in The American journal of Chinese medicine (1979) (2019)“…Hook F. (TWHF), a traditional Chinese medicine, has been widely used to treat autoimmune and inflammatory diseases including rheumatoid arthritis, systemic…”
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Abstract P381: Diabetes Prevention Program Football Club: A 6-month Intervention Among Latino Men
Published in Circulation (New York, N.Y.) (03-03-2020)“…Abstract only Purpose: One third of the U.S. adult population is estimated to have prediabetes. Hispanics have a 50% higher type 2 diabetes (T2DM) death rate…”
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Isoliquiritigenin triggers developmental toxicity and oxidative stress–mediated apoptosis in zebrafish embryos/larvae via Nrf2-HO1/JNK-ERK/mitochondrion pathway
Published in Chemosphere (Oxford) (01-05-2020)“…Isoliquiritigenin (ISL) is an emerging natural flavonoid found in the roots of licorice, exhibits antioxidant, anti-cancer, anti-inflammatory, anti-allergic,…”
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Discovery of new cyclopropane sulfonamide derivatives as EGFR inhibitors to overcome C797S-mediated resistance and EGFR double mutation
Published in European journal of medicinal chemistry (05-09-2024)“…The C797S mutation of EGFR leads to Osimertinib resistance by blocking the covalent binding of Cys797. To develop new agents that can overcome EGFR mutation…”
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