Search Results - "Li, Jian H."

Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1 by Scott, Iain, Webster, Bradley R, Li, Jian H, Sack, Michael N

“…SIRT3 (sirtuin 3) modulates respiration via the deacetylation of lysine residues in electron transport chain proteins. Whether mitochondrial protein…”
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Combination of secretin and fluvastatin ameliorates the polyuria associated with X-linked nephrogenic diabetes insipidus in mice by Procino, Giuseppe, Milano, Serena, Carmosino, Monica, Barbieri, Claudia, Nicoletti, Maria C, Li, Jian H, Wess, Jürgen, Svelto, Maria

“…X-linked nephrogenic diabetes insipidus (X-NDI) is a disease caused by inactivating mutations of the vasopressin (AVP) type 2 receptor (V2R) gene. Loss of V2R…”
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Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage by Mistry, Pramod K., Liu, Jun, Yang, Mei, Nottoli, Timothy, McGrath, James, Jain, Dhanpat, Zhang, Kate, Keutzer, Joan, Chuang, Wei-Lein, Mehal, Wajahat Z., Zhao, Hongyu, Lin, Aiping, Mane, Shrikant, Liu, Xuan, Peng, Yuan Z., Li, Jian H., Agrawal, Manasi, Zhu, Ling-Ling, Blair, Harry C., Robinson, Lisa J., Iqbal, Jameel, Sun, Li, Zaidi, Mone, New, Maria I.

“…In nonneuronopathic type 1 Gaucher disease (GD1), mutations in the glucocerebrosidase gene (GBA1) gene result in glucocerebrosidase deficiency and the…”
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Restricted mitochondrial protein acetylation initiates mitochondrial autophagy by Webster, Bradley R, Scott, Iain, Han, Kim, Li, Jian H, Lu, Zhongping, Stevens, Mark V, Malide, Daniela, Chen, Yong, Samsel, Leigh, Connelly, Patricia S, Daniels, Mathew P, McCoy, Jr, J Philip, Combs, Christian A, Gucek, Marjan, Sack, Michael N

“…Because nutrient-sensing nuclear and cytosolic acetylation mediates cellular autophagy, we investigated whether mitochondrial acetylation modulates…”
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SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity by Lu, Zhongping, Bourdi, Mohammed, Li, Jian H, Aponte, Angel M, Chen, Yong, Lombard, David B, Gucek, Marjan, Pohl, Lance R, Sack, Michael N

“…Acetaminophen/paracetamol‐induced liver failure—which is induced by the binding of reactive metabolites to mitochondrial proteins and their disruption—is…”
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Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice by Li, Jian H, Gautam, Dinesh, Han, Sung-Jun, Guettier, Jean-Marc, Cui, Yinghong, Lu, Huiyan, Deng, Chuxia, O'Hare, James, Jou, William, Gavrilova, Oksana, Buettner, Christoph, Wess, Jürgen

“…Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice Jian H. Li 1 , Dinesh Gautam 1 , Sung-Jun Han…”
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The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA by Thapa, Dharendra, Wu, Kaiyuan, Stoner, Michael W., Xie, Bingxian, Zhang, Manling, Manning, Janet R., Lu, Zhongping, Li, Jian H., Chen, Yong, Gucek, Marjan, Playford, Martin P., Mehta, Nehal N., Harmon, Daniel, O’Doherty, Robert M., Jurczak, Michael J., Sack, Michael N., Scott, Iain

“…Sirtuin 3 (SIRT3) deacetylates and activates several mitochondrial fatty acid oxidation enzymes in the liver. Here, we investigated whether the protein…”
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Beneficial metabolic effects of M3 muscarinic acetylcholine receptor deficiency by Gautam, Dinesh, Gavrilova, Oksana, Jeon, Jongrye, Pack, Stephanie, Jou, William, Cui, Yinghong, Li, Jian H, Wess, Jürgen

“…Most animal models of obesity and hyperinsulinemia are associated with increased vagal cholinergic activity. The M3 muscarinic acetylcholine receptor subtype…”
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Orthopedic Surgery Matched Applicants Are Publishing More: A Bibliometric Analysis of Research Output by Abbas, Anas M, Li, Jian H, Pandya, Aadi, Wang, Victoria, Jung, Bongseok, Echevarria, Alexandra C, Abbas, Araf M, Carrier, Robert E, Cemenski, Brandon, Verma, Rohit B, Albanese, Stephen A, Cohn, Randy M

“…Introduction This study analyzed the number of peer-reviewed publications submitted by matriculants prior to applying for the orthopedic surgery residency. The…”
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Pronounced Conformational Changes following Agonist Activation of the M3 Muscarinic Acetylcholine Receptor by Han, Sung-Jun, Hamdan, Fadi F., Kim, Soo-Kyung, Jacobson, Kenneth A., Brichta, Lars, Bloodworth, Lanh M., Li, Jian H., Wess, Jürgen

“…The conformational changes that convert G protein-coupled receptors (GPCRs) activated by diffusible ligands from their resting into their active states are not…”
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Effects of an early lipopolysaccharide challenge on growth and small intestinal structure and function of broiler chickens by Hu, Xiao F., Guo, Yu M., Li, Jian H., Yan, Gui L., Bun, Sideoun, Huang, Bei Y.

“…Hu, X. F., Guo, Y. M., Li, J. H., Yan, G. L., Bun, S. and Huang, B. Y. 2011. Effects of an early lipopolysaccharide challenge on growth and small intestinal…”
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Interactive Effects of Elevated CO2 and Temperature on Rice Planthopper, Nilaparvata lugens by SHI, Bao-kun, HUANG, Jian-li, HU, Chao-xing, HOU, Mao-lin

“…It is predicted that the current atmospheric CO2 concentration will be doubled and global mean temperature will increase by 1.5-6＆#176;C by the end of this…”
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Evaluation of HO-1 expression, cellular ROS production, cellular proliferation and cellular apoptosis in human esophageal squamous cell carcinoma tumors and cell lines by REN, QUAN-GUANG, YANG, SHENG-LI, HU, JIAN-LI, LI, PIN-DONG, CHEN, YE-SHAN, WANG, QIU-SHUANG

“…Patients with esophageal squamous cell carcinoma (ESCC) have a poor prognosis. However, the related mechanisms are unclear, thus we investigated the expression…”
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Preoperative Narcotic Education in Spine Surgery: A Retrospective Study by Abbas, Anas M., Ngan, Alex, Li, Jian H., Abbas, Araf M., Pandya, Aadi, Ahmad, Salman, Jung, Bongseok, Shahsavarani, Shaya, Verma, Rohit B.

“…Background/Objectives: The objective of this study was to determine whether preoperative opioid education reduces opioid consumption after spine surgery and…”
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Beneficial metabolic effects of M 3 muscarinic acetylcholine receptor deficiency by Gautam, Dinesh, Gavrilova, Oksana, Jeon, Jongrye, Pack, Stephanie, Jou, William, Cui, Yinghong, Li, Jian H., Wess, Jürgen

“…Most animal models of obesity and hyperinsulinemia are associated with increased vagal cholinergic activity. The M 3 muscarinic acetylcholine receptor subtype…”
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Effects of an early lipopolysaccharide challenge on growth and small intestinal structure and function of broiler chickens by Hu, Xiao, Guo, Yu, Li, Jian, Yan, Gui, Bun, Sideoun, Huang, Bei

“…Hu, X. F., Guo, Y. M., Li, J. H., Yan, G. L., Bun, S. and Huang, B. Y. 2011. Effects of an early lipopolysaccharide challenge on growth and small intestinal…”
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Identification of PAQR3 as a new candidate tumor suppressor in hepatocellular carcinoma by WU, HONG GE, ZHANG, WEN JIE, DING, QIAN, PENG, GANG, ZOU, ZHEN WEI, LIU, TING, CAO, RU BO, FEI, SHI JIANG, LI, PENG CHENG, YANG, KUN YU, HU, JIAN LI, DAI, XIANG FANG, WU, GANG, LI, PIN DONG

“…Progestin and adipoQ receptor family member III (PAQR3) is a regulator that negatively modulates the Ras/Raf/MEK/ERK signaling cascade and the GPCR Gβγ subunit…”
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Hepatitis B virus induces hypoxia-inducible factor-2α expression through hepatitis B virus X protein by HU, JIAN-LI, LIU, LI-PING, YANG, SHENG-LI, FANG, XIEFAN, WEN, LU, REN, QUAN-GUANG, YU, CHAO

“…A growing number of studies suggest that the hepatitis B virus X protein (HBx) enhances the protein stability of the hypoxia-inducible factor-1α (HIF-1α)…”
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Identification of distinct, ligand‐specific structural changes in a G protein‐coupled receptor by Li, Jian H, Han, Sung‐Jun, Hamdan, Fadi F., Kim, Soo‐Kyung, Jacobson, Kenneth A, Bloodworth, Lanh M., Zhang, Xiaohong, Wess, Jurgen

“…G protein‐coupled receptors (GPCRs) represent by far the largest class of cell surface receptors. The conformational changes in GPCR structure induced by GPCR…”
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Pronounced conformational changes following agonist activation of the M(3) muscarinic acetylcholine receptor by Han, Sung-Jun, Hamdan, Fadi F, Kim, Soo-Kyung, Jacobson, Kenneth A, Brichta, Lars, Bloodworth, Lanh M, Li, Jian H, Wess, Jürgen

“…The conformational changes that convert G protein-coupled receptors (GPCRs) activated by diffusible ligands from their resting into their active states are not…”
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