Search Results - "Li, Jia‐Da"

The Roles of Post-translational Modifications on α-Synuclein in the Pathogenesis of Parkinson's Diseases by Zhang, Jiaming, Li, Xiaoping, Li, Jia-Da

“…Parkinson's disease is the second most common neurodegenerative disorder. Although the pathogenesis of Parkinson's disease is not entirely clear, the aberrant…”
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A genome‐wide CRISPR screen identifies USP1 as a novel regulator of the mammalian circadian clock by Hu, Ying, Li, Xin, Zhang, Jing, Liu, Dengfeng, Lu, Renbin, Li, Jia‐Da

“…The circadian clock is generated by a molecular timekeeping mechanism coordinating daily oscillations of physiology and behaviors in mammals. In the mammalian…”
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Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery by Lu, Renbin, Dong, Yufan, Li, Jia-Da

“…Abstract Circadian clocks are endogenous oscillators that control ∼24-hour physiology and behaviors in virtually all organisms. The circadian oscillator…”
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Identification of a Novel CNV at 8q13 in a Family With Branchio‐Oto‐Renal Syndrome and Epilepsy by Men, Meichao, Li, Wu, Chen, Hongsheng, Wu, Jiayu, Feng, Yong, Guo, Hui, Li, Jia‐Da

“…Objectives Branchio‐oto‐renal (BOR) syndrome is characterized by branchial defects, hearing loss, preauricular pits, and renal anomalies, whereas patients with…”
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Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance by Zhang, Hui, Fredericks, Tricia, Xiong, Gaofeng, Qi, Yifei, Rychahou, Piotr G, Li, Jia-Da, Pihlajaniemi, Taina, Xu, Wei, Xu, Ren

“…Increased collagen expression and deposition are associated with cancer progression and poor prognosis in breast cancer patients. However, function and…”
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RORα Suppresses Cancer-Associated Inflammation by Repressing Respiratory Complex I-Dependent ROS Generation by Mao, Wei, Xiong, Gaofeng, Wu, Yuanyuan, Wang, Chi, St Clair, Daret, Li, Jia-Da, Xu, Ren

“…Breast cancer development is associated with macrophage infiltration and differentiation in the tumor microenvironment. Our previous study highlights the…”
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Suppression of Akt-mTOR pathway rescued the social behavior in Cntnap2-deficient mice by Xing, Xiaoliang, Zhang, Jing, Wu, Kunyang, Cao, Beibei, Li, Xianfeng, Jiang, Fang, Hu, Zhengmao, Xia, Kun, Li, Jia-Da

“…Autism spectrum disorders (ASD) form a heterogeneous, neurodevelopmental syndrome characterized by deficits in social interactions and repetitive…”
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Phenotypic Spectrum of Idiopathic Hypogonadotropic Hypogonadism Patients With CHD7 Variants From a Large Chinese Cohort by Li, Jia-Da, Wu, Jiayu, Zhao, Yaguang, Wang, Xinying, Jiang, Fang, Hou, Qiao, Chen, Dan-Na, Zheng, Ruizhi, Yu, Renhe, Zhou, Wei, Men, Meichao

“…Abstract Purpose Idiopathic hypogonadotropic hypogonadism (IHH) and CHARGE (C, coloboma; H, heart abnormalities; A, choanal atresia, R, retardation of growth…”
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Functional analysis of SEMA3A variants identified in Chinese patients with isolated hypogonadotropic hypogonadism by Dai, Wenting, Li, Jia‐Da, Zhao, Yaguang, Wu, Jiayu, Jiang, Fang, Chen, Dan‐Na, Zheng, Ruizhi, Men, Meichao

“…Isolated hypogonadotropic hypogonadism (IHH) is a rare disorder characterized by impaired sexual development and infertility, caused by the deficiency of…”
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Locus-specific DNA methylation of Mecp2 promoter leads to autism-like phenotypes in mice by Lu, Zongyang, Liu, Zhen, Mao, Wei, Wang, Xinying, Zheng, Xiaoguo, Chen, Shanshan, Cao, Beibei, Huang, Shisheng, Zhang, Xuliang, Zhou, Tao, Zhang, Yu, Huang, Xingxu, Sun, Qiang, Li, Jia-Da

“…Autism spectrum disorder (ASD) is a neurodevelopmental disease with a strong heritability, but recent evidence suggests that epigenetic dysregulation may also…”
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RNF216 regulates meiosis and PKA stability in the testes by Li, Dengfeng, Li, Fangfang, Meng, Lanlan, Wei, Huafang, Zhang, Qianjun, Jiang, Fang, Chen, Dan‐Na, Li, Wei, Tan, Yue‐Qiu, Li, Jia‐Da

“…Spermatogenesis is a highly sophisticated process that comprises of mitosis, meiosis, and spermiogenesis. RNF216 (ring finger protein 216), an E3 ubiquitin…”
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KAT8/SIRT7‐mediated Fascin‐K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma by Li, Da‐Jia, Cheng, Yin‐Wei, Pan, Jin‐Mei, Guo, Zhen‐Chang, Wang, Shao‐Hong, Huang, Qing‐Feng, Nie, Ping‐Juan, Shi, Wen‐Qi, Xu, Xiu‐E, Wen, Bing, Zhong, Jin‐Ling, Zhang, Zhi‐Da, Wu, Zhi‐Yong, Zhao, Hui, Liao, Lian‐Di, Wu, Jian‐Yi, Zhang, Kai, Dong, Geng, Li, En‐Min, Xu, Li‐Yan

“…Fascin actin‐bundling protein 1 (Fascin) is highly expressed in a variety of cancers, including esophageal squamous cell carcinoma (ESCC), working as an…”
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Use of artificial intelligence to recover mandibular morphology after disease by Liang, Ye, Huan, JingJing, Li, Jia-Da, Jiang, CanHua, Fang, ChangYun, Liu, YongGang

“…Mandibular tumors and radical oral cancer surgery often cause bone dysmorphia and defects. Most patients present with noticeable mandibular deformations, and…”
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FMRP binds Per1 mRNA and downregulates its protein expression in mice by Tang, Xiangrong, Zhang, Jing, Li, Xin, Hu, Ying, Liu, Dengfeng, Li, Jia-Da, Lu, Renbin

“…FMRP, an RNA-binding protein, has previously shown to be involved in regulation of circadian rhythms in flies and mice. However, the molecular mechanism…”
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Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia by Shi, Yuting, Wang, Junling, Li, Jia-Da, Ren, Haigang, Guan, Wenjuan, He, Miao, Yan, Weiqian, Zhou, Ying, Hu, Zhengmao, Zhang, Jianguo, Xiao, Jingjing, Su, Zheng, Dai, Meizhi, Wang, Jun, Jiang, Hong, Guo, Jifeng, Zhou, Yafang, Zhang, Fufeng, Li, Nan, Du, Juan, Xu, Qian, Hu, Yacen, Pan, Qian, Shen, Lu, Wang, Guanghui, Xia, Kun, Zhang, Zhuohua, Tang, Beisha

“…Autosomal recessive cerebellar ataxias are a group of neurodegenerative disorders that are characterized by complex clinical and genetic heterogeneity…”
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Oxytocin inhibits the activity of acid‐sensing ion channels through the vasopressin, V1A receptor in primary sensory neurons by Qiu, Fang, Qiu, Chun‐Yu, Cai, Huilan, Liu, Ting‐Ting, Qu, Zu‐Wei, Yang, Zhifan, Li, Jia‐Da, Zhou, Qun‐Yong, Hu, Wang‐Ping

“…Background and Purpose A growing number of studies have demonstrated that oxytocin (OT) plays an analgesic role in modulation of nociception and pain. Most…”
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A model‐based tracking method for measuring 3D dynamic joint motion using an alternating biplane x‐ray imaging system by Lin, Cheng‐Chung, Li, Jia‐Da, Lu, Tung‐Wu, Kuo, Mei‐Ying, Kuo, Chien‐Chung, Hsu, Horng‐Chaung

“…Purposes To propose a new model‐based tracking method for measuring three‐dimensional (3D) dynamic joint kinematics using a clinical alternating biplane x‐ray…”
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Use of three points to determine the accuracy of guided implantation by Liang, Ye, Yuan, ShanShan, Huan, JingJing, Wang, HuiXin, Zhang, YiYi, Fang, ChangYun, Li, Jia-Da

“…'This study aims to establish an open-source algorithm using Python to analyze the accuracy of guided implantation, which simplifies interstudy comparisons…”
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Discovery of a Novel Variant of SEMA3A in a Chinese Patient with Isolated Hypogonadotropic Hypogonadism by Dai, Wenting, Li, Jia-Da, Wang, Xinying, Zeng, Wang, Jiang, Fang, Zheng, Ruizhi

“…Semaphorin (SEMA) has an important role in nerve development, organ formation, immune response, angiogenesis, and tumor growth. SEMA can regulate the growth…”
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Vasopressin receptor V1a regulates circadian rhythms of locomotor activity and expression of clock-controlled genes in the suprachiasmatic nuclei by Li, Jia-Da, Burton, Katherine J, Zhang, Chengkang, Hu, Shuang-Bao, Zhou, Qun-Yong

“…The suprachiasmatic nuclei (SCN) serve as the principal circadian pacemakers that coordinate daily cycles of behavior and physiology for mammals. A network of…”
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