Search Results - "Li, Hung Wing"

Ultrasensitive miRNA Detection by AuNP‐based 3D DNA Walker and Catalytic Hairpin Assembly (CHA) Cascade Amplification for Early Cancer Diagnosis by Li, Junyou, Li, Hung‐Wing

“…By combining exquisitely designed hairpins with the catalytic hairpin assembly (CHA) to form tripedal DNA walkers driven by enzyme, we constructed a 3D DNA…”
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2D MOF Nanosensor‐Integrated Digital Droplet Microfluidic Flow Cytometry for In Situ Detection of Multiple miRNAs in Single CTC Cells by Chen, Junyue, Oudeng, Gerile, Feng, Hongtao, Liu, Sixi, Li, Hung‐Wing, Ho, Yi‐Ping, Chen, Yan, Tan, Ying, Yang, Mo

“…Current circulating tumor cells (CTCs) detection strategies based on surface epithelial markers suffer from low specificity in distinguishing between CTCs and…”
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The morphology and surface charge-dependent cellular uptake efficiency of upconversion nanostructures revealed by single-particle optical microscopy by Zhang, Di, Wei, Lin, Zhong, Meile, Xiao, Lehui, Li, Hung-Wing, Wang, Jianfang

“…The cellular uptake efficiency of nanostructures has been demonstrated to be highly dependent on the surface charge, size and shape although the cellular…”
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Amyloid‐β Oligomer‐Targeted Gadolinium‐Based NIR/MR Dual‐Modal Theranostic Nanoprobe for Alzheimer's Disease by Wang, Chengke, Wang, Xueli, Chan, Hei‐Nga, Liu, Guifeng, Wang, Zhenxin, Li, Hung‐Wing, Wong, Man Shing

“…While the deposition of amyloid‐β (Aβ) plaques is one of the main pathological hallmarks of incurable Alzheimer's disease (AD), Aβ oligomers have been…”
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Rapid and ultrasensitive detection of food contaminants using surface-enhanced Raman spectroscopy-based methods by Guo, Yahui, Girmatsion, Mogos, Li, Hung-Wing, Xie, Yunfei, Yao, Weirong, Qian, He, Abraha, Bereket, Mahmud, Abdu

“…With the globalization of food and its complicated networking system, a wide range of food contaminants is introduced into the food system which may happen…”
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Dual‐Modal NIR‐Fluorophore Conjugated Magnetic Nanoparticle for Imaging Amyloid‐β Species In Vivo by Li, Yinhui, Xu, Di, Chan, Hei‐Nga, Poon, Chung‐Yan, Ho, See‐Lok, Li, Hung‐Wing, Wong, Man Shing

“…Senile plaques, the extracellular deposit of amyloid‐β (Aβ) peptides, are one of the neuropathological hallmarks found in Alzheimer's disease (AD) brain. The…”
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Saccharide‐Functionalized Poly(Zn‐salphen)‐alt‐(m‐ and p‐phenyleneethynylene)s as Dynamic Helical Metallopolymers by Zhao, Chao, Meng, Shuangshuang, Chan, Hei‐Nga, Wang, Xueli, Li, Hung‐Wing, Chan, Michael C. W.

“…The study of metallopolymers with controllable helical sense remains in its infancy. We report arabinose‐functionalized (Zn‐salphen)‐based conjugated polymers…”
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A Zero Cross-Talk Ratiometric Two-Photon Probe for Imaging of Acid pH in Living Cells and Tissues and Early Detection of Tumor in Mouse Model by Xu, Di, Li, Yinhui, Poon, Chung-Yan, Chan, Hei-Nga, Li, Hung-Wing, Wong, Man Shing

“…Acid–base disorders disrupt proper cellular functions, which are associated with diverse diseases. Development of highly sensitive pH probes being capable of…”
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Enzyme-free quantification of exosomal microRNA by the target-triggered assembly of the polymer DNAzyme nanostructure by He, Dinggeng, Hai, Luo, Wang, Huizhen, Wu, Ri, Li, Hung-Wing

“…We herein report an efficient hybridization chain reaction (HCR)- and DNAzyme-based enzyme-free signal amplification for the detection of specific exosomal…”
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Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activation by You, Ran, Ho, Yuen-Shan, Hung, Clara Hiu-Ling, Liu, Yan, Huang, Chun-Xia, Chan, Hei-Nga, Ho, See-Lok, Lui, Sheung-Yeung, Li, Hung-Wing, Chang, Raymond Chuen-Chung

“…Silica nanoparticles (SiO -NPs) are naturally enriched and broadly utilized in the manufacturing industry. While previous studies have demonstrated toxicity in…”
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A fluorometric assay of thrombin using magnetic nanoparticles and enzyme-free hybridization chain reaction by Huang, Zhongming, He, Dinggeng, Li, Hung-Wing

“…A fluorescence method based on functionalized magnetic nanoparticles (FMNPs) and hybridization chain reaction (HCR) is developed for the enzyme-free amplified…”
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A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles by Hou, Min, He, Dinggeng, Bu, Hongchang, Wang, Huizhen, Huang, Jin, Gu, Jinqing, Wu, Ri, Li, Hung-Wing, He, Xiaoxiao, Wang, Kemin

“…A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for…”
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Total internal reflection-based single-vesicle in situ quantitative and stoichiometric analysis of tumor-derived exosomal microRNAs for diagnosis and treatment monitoring by He, Dinggeng, Wang, Huizhen, Ho, See-Lok, Chan, Hei-Nga, Hai, Luo, He, Xiaoxiao, Wang, Kemin, Li, Hung-Wing

“…: Exosomes (EXs) have been increasingly recognized as natural nanoscale vehicles for microRNA (miRNA)-based cell-cell communication and an ideal source of…”
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Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity by Li, Yinhui, Xu, Di, Sun, Anyang, Ho, See-Lok, Poon, Chung-Yan, Chan, Hei-Nga, Ng, Olivia T W, Yung, Ken K L, Yan, Hui, Li, Hung-Wing, Wong, Man Shing

“…Alzheimer's disease (AD) is the most prevalent but still incurable neurodegenerative form of dementia. Early diagnosis and intervention are crucial for…”
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The light-up fluorescence of AgNCs in a "DNA bulb" by Guo, Yahui, Shen, Fumiao, Cheng, Yuliang, Xie, Yunfei, Yu, Hang, Yao, Weirong, Li, Hung-Wing, Qian, He, Pei, Renjun

“…In this presented work, a series of designs and experiments have been constructed to study how a DNA structure affected the fluorescence of silver nanoclusters…”
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Self-assembled palladium nanoflowers supported on fullerene: Electrochemical catalytic performance for the reduction of 4-nitrophenol by Li, Zhongping, Zhang, Yuxin, Zhu, Ruiqi, Wen, Guangming, Dong, Chuan, Li, Hung-Wing

“…Loading metal nanoparticles on the surface of nanosheet supports is an attractive approach to enhancing their catalytic performance. Herein, palladium…”
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FRET-based modified graphene quantum dots for direct trypsin quantification in urine by Poon, Chung-Yan, Li, Qinghua, Zhang, Jiali, Li, Zhongping, Dong, Chuan, Lee, Albert Wai-Ming, Chan, Wing-Hong, Li, Hung-Wing

“…A versatile nanoprobe was developed for trypsin quantification with fluorescence resonance energy transfer (FRET). Here, fluorescence graphene quantum dot is…”
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Nanomaterials that Aid in the Diagnosis and Treatment of Alzheimer's Disease, Resolving Blood–Brain Barrier Crossing Ability by Song, Qingting, Li, Junyou, Li, Ting, Li, Hung‐Wing

“…As a form of dementia, Alzheimer's disease (AD) suffers from no efficacious cure, yet AD treatment is still imperative, as it ameliorates the symptoms or…”
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Simultaneous and multiplex detection of exosomal microRNAs based on the asymmetric Au@Au@Ag probes with enhanced Raman signal by Hou, Min, He, Dinggeng, Wang, Huizhen, Huang, Jin, Cheng, Hong, Wan, Kejin, Li, Hung-Wing, Tang, Zifeng, He, Xiaoxiao, Wang, Kemin

“…Simultaneous and quantitative detection of multiple exosomal microRNAs (miRNAs) was successfully performed by a surface-enhanced Raman scattering (SERS) assay…”
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Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes by Lu, Lihua, Zhong, Hai-Jing, Wang, Modi, Ho, See-Lok, Li, Hung-Wing, Leung, Chung-Hang, Ma, Dik-Lung

“…We report herein the application of kinetically inert luminescent iridium(III) complexes as dual inhibitors and probes of beta-amyloid fibrillogenesis. These…”
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