Search Results - "Li, Huchun"

Direct interaction between BRCA1 and the estrogen receptor regulates vascular endothelial growth factor (VEGF) transcription and secretion in breast cancer cells by KAWAI, Hideki, HUCHUN LI, PHILIP CHUN, AVRAHAM, Shalom, HAVA KARSENTY AVRAHAM

“…Mutational inactivation of BRCA1 confers increased risk for breast cancer. However, the underlying basis for the breast tissue-restricted, tumor-suppressive…”
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BRCA1 interacts with Smad3 and regulates Smad3-mediated TGF-beta signaling during oxidative stress responses by Li, Huchun, Sekine, Masayuki, Seng, Seyha, Avraham, Shalom, Avraham, Hava Karsenty

“…BRCA1 is a key regulatory protein participating in cell cycle checkpoint and DNA damage repair networks. BRCA1 plays important roles in protecting numerous…”
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A Novel Tricomplex of BRCA1, Nmi, and c-Myc Inhibits c-Myc-induced Human Telomerase Reverse Transcriptase Gene (hTERT) Promoter Activity in Breast Cancer by Li, Huchun, Lee, Tae-Hee, Avraham, Hava

“…Germ-line mutations in BRCA1 predispose individuals to breast and ovarian cancers. We observed a novel endogenous association of BRCA1 with Nmi…”
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The nuclear matrix protein, NRP/B, enhances Nrf2-mediated oxidative stress responses in breast cancer cells by SENG, Seyha, AVRAHAM, Hava Karsenty, SHUXIAN JIANG, SUPING YANG, SEKINE, Masayuki, KIMELMAN, Noam, HUCHUN LI, AVRAHAM, Shalom

“…The transcription factor NF-E2-related factor 2 (Nrf2) translocates into the nucleus and activates phase II genes encoding detoxification enzymes and…”
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Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: Nuclear HO-1 promotes vascular endothelial growth factor secretion by BIRRANE, GABRIEL, LI, HUCHUN, YANG, SUPING, TACHADO, SOUVENIR D, SENG, SEYHA

“…Prostate cancer is the second leading cause of male-cancer related death in the United States. Despite a number of evidence-based studies which strongly…”
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Transcriptional Activating Activity of Smad4: Roles of SMAD Hetero-Oligomerization and Enhancement by an Associating Transactivator by Shioda, Toshi, Lechleider, Robert J., Dunwoodie, Sally L., Li, Huchun, Yahata, Tetsuro, De Caestecker, Mark P., Fenner, Martin H., Roberts, Anita B., Isselbacher, Kurt J.

“…Smad4 plays a pivotal role in signal transduction of the transforming growth factor β superfamily cytokines by mediating transcriptional activation of target…”
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Integrin Regulation by Vascular Endothelial Growth Factor in Human Brain Microvascular Endothelial Cells by Lee, Tae-Hee, Seng, Seyha, Li, Huchun, Kennel, Stephen J., Avraham, Hava Karsenty, Avraham, Shalom

“…The precise role of vascular endothelial growth factor (VEGF) in regulating integrins in brain microvascular endothelial cells is unknown. Here, we analyzed…”
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Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor α by Kawai, Hideki, Li, Huchun, Avraham, Shalom, Jiang, Shuxian, Avraham, Hava Karsenty

“…The interaction between 17β‐estradiol and estrogen receptor alpha (ER‐α) plays an important role in breast carcinogenesis and breast cancer treatment. ER‐α is…”
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Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-catenin by Li, Huchun, Sekine, Masayuki, Tung, Nadine, Avraham, Hava Karsenty

“…BRCA1 is an essential caretaker protein in the surveillance of DNA damage, is mutated in approximately 50% of all hereditary breast cancer cases, and its…”
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Integrin Regulation by Vascular Endothelial Growth Factor in Human Brain Microvascular Endothelial Cells: ROLE OF α₆β₁ INTEGRIN IN ANGIOGENESIS by Lee, Tae-Hee, Seng, Seyha, Li, Huchun, Kennel, Stephen J, Avraham, Hava Karsenty, Avraham, Shalom

“…The precise role of vascular endothelial growth factor (VEGF) in regulating integrins in brain microvascular endothelial cells is unknown. Here, we analyzed…”
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RAFTK/Pyk2 regulates EGF-induced PC12 cell spreading and movement by Park, Shin-Young, Li, Huchun, Avraham, Shalom

“…The protein tyrosine kinase RAFTK, also termed Pyk2, is a member of the focal adhesion kinase (FAK) subfamily. In this report, we show the role of RAFTK in…”
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BRCA1 Interacts with Smad3 and Regulates Smad3-Mediated TGF-[beta] Signaling during Oxidative Stress Responses by Li, Huchun, Sekine, Masayuki, Seng, Seyha, Avraham, Shalom, Avraham, Hava Karsenty

“…Background BRCA1 is a key regulatory protein participating in cell cycle checkpoint and DNA damage repair networks. BRCA1 plays important roles in protecting…”
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Integrin regulation by vascular endothelial growth factor in human brain microvascular endothelial cells: role of alpha6beta1 integrin in angiogenesis by Lee, Tae-Hee, Seng, Seyha, Li, Huchun, Kennel, Stephen J, Avraham, Hava Karsenty, Avraham, Shalom

“…The precise role of vascular endothelial growth factor (VEGF) in regulating integrins in brain microvascular endothelial cells is unknown. Here, we analyzed…”
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Integrin Regulation by Vascular Endothelial Growth Factor in Human Brain Microvascular Endothelial Cells: ROLE OF alpha sub(6) beta sub(1) INTEGRIN IN ANGIOGENESIS by Lee, Tae-Hee, Seng, Seyha, Li, Huchun, Kennel, Stephen J, Avraham, Hava Karsenty, Avraham, Shalom

“…The precise role of vascular endothelial growth factor (VEGF) in regulating integrins in brain microvascular endothelial cells is unknown. Here, we analyzed…”
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Regulation of Integrin Expression and Activation by VEGF in Human Brain Microvascular Endothelial Cells: Implication of α6 Integrin in Angiogenesis by Lee, Tae-Hee, Avraham, Hava Karsenty, Li, Huchun, Kennel, Stephen J., Avraham, Shalom

“…The precise role of vascular endothelial growth factor (VEGF) in the regulation of integrins is not well elucidated due to their high redundancy. Here, we…”
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Regulation of Expression of MSG1 Melanocyte-Specific Nuclear Protein in Human Melanocytes and Melanoma Cells by Li, Huchun, Ahmed, Nazim U., Fenner, Martin H., Ueda, Masato, Isselbacher, Kurt J., Shioda, Toshi

“…MSG1 is a nuclear protein and a possible transcriptional transactivator that is expressed strongly in melanocytes but very weakly, if at all, in most…”
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