Search Results - "Li, Huawei"

Influence of drop weight geometry and interlayer on impact behavior of RC beams by Li, Huawei, Chen, Wensu, Hao, Hong

“…•The influence of drop weight geometry on impact behavior.•The effect of interlayer on impact behavior.•The effect of initial inclination angle on impact…”
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Factors influencing impact force profile and measurement accuracy in drop weight impact tests by Li, Huawei, Chen, Wensu, Hao, Hong

“…•Measurement methods of impact force are summarized.•The influence of drop weight mass distribution on impact force measurement.•The effect of load cell…”
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Effects of regulating gut microbiota on the serotonin metabolism in the chronic unpredictable mild stress rat model by Li, Huawei, Wang, Peng, Huang, Luqiao, Li, Ping, Zhang, Dianliang

“…Objective This study was to inspect the antidepressant‑like effect of prebiotics and probiotics, and to explore the effect of modulating gut microbiota on the…”
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Wnt/β-catenin interacts with the FGF pathway to promote proliferation and regenerative cell proliferation in the zebrafish lateral line neuromast by Tang, Dongmei, He, Yingzi, Li, Wenyan, Li, Huawei

“…Wnt and FGF are highly conserved signaling pathways found in various organs and have been identified as important regulators of auditory organ development. In…”
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AAV-ie enables safe and efficient gene transfer to inner ear cells by Tan, Fangzhi, Chu, Cenfeng, Qi, Jieyu, Li, Wenyan, You, Dan, Li, Ke, Chen, Xin, Zhao, Weidong, Cheng, Cheng, Liu, Xiaoyi, Qiao, Yunbo, Su, Bing, He, Shuijin, Zhong, Chao, Li, Huawei, Chai, Renjie, Zhong, Guisheng

“…Hearing loss is the most common sensory disorder. While gene therapy has emerged as a promising treatment of inherited diseases like hearing loss, it is…”
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Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea by Chen, Yan, Gu, Yuyan, Li, Yige, Li, Geng-Lin, Chai, Renjie, Li, Wenyan, Li, Huawei

“…The mammalian cochlea cannot regenerate functional hair cells (HCs) spontaneously. Atoh1 overexpression as well as other strategies are unable to generate…”
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Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway by Li, Wenyan, Wu, Jingfang, Yang, Jianming, Sun, Shan, Chai, Renjie, Chen, Zheng-Yi, Li, Huawei

“…The activation of cochlear progenitor cells is a promising approach for hair cell (HC) regeneration and hearing recovery. The mechanisms underlying the…”
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On the accuracy, reliability and controllability of impact tests of RC beams by Hao, Hong, Tran, Tung T., Li, Huawei, Pham, Thong M., Chen, Wensu

“…•Unveil reason for negative reaction force in drop-weight impact tests.•Discuss and recommendation for reliable measurement of impact force.•Discuss and…”
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Autophagy protects auditory hair cells against neomycin-induced damage by He, Zuhong, Guo, Lingna, Shu, Yilai, Fang, Qiaojun, Zhou, Han, Liu, Yongze, Liu, Dingding, Lu, Ling, Zhang, Xiaoli, Ding, Xiaoqiong, Liu, Dong, Tang, Mingliang, Kong, Weijia, Sha, Suhua, Li, Huawei, Gao, Xia, Chai, Renjie

“…Aminoglycosides are toxic to sensory hair cells (HCs). Macroautophagy/autophagy is an essential and highly conserved self-digestion pathway that plays…”
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Vestibular Dysfunctions in Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis by Yu, Huiqian, Li, Huawei

“…Sudden sensorineural hearing loss (SSHL) not only involves cochlear function but might also be accompanied by vestibular disturbances. The assessment of…”
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SoundMind Trial: a study protocol for a randomised controlled trial for online acceptance and commitment therapy and sound therapy for tinnitus by Huang, Xiaoling, Tang, Dongmei, Sun, Shan, Li, Huawei

“…IntroductionTinnitus is a common ailment that affects 10%–15% of adults worldwide. Comorbidities associated with tinnitus often include hearing loss, emotional…”
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HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells by Zhang, Haojian, Li, Huawei, Xi, Hualin S., Li, Shaoguang

“…Hypoxia-inducible factor-1α (HIF1α), a master transcriptional regulator of the cellular and systemic hypoxia response, is essential for the maintenance of…”
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Prevention of acquired sensorineural hearing loss in mice by in vivo Htra2 gene editing by Gu, Xi, Wang, Daqi, Xu, Zhijiao, Wang, Jinghan, Guo, Luo, Chai, Renjie, Li, Genglin, Shu, Yilai, Li, Huawei

“…Aging, noise, infection, and ototoxic drugs are the major causes of human acquired sensorineural hearing loss, but treatment options are limited. CRISPR/Cas9…”
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AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial by Lv, Jun, Wang, Hui, Cheng, Xiaoting, Chen, Yuxin, Wang, Daqi, Zhang, Longlong, Cao, Qi, Tang, Honghai, Hu, Shaowei, Gao, Kaiyu, Xun, Mengzhao, Wang, Jinghan, Wang, Zijing, Zhu, Biyun, Cui, Chong, Gao, Ziwen, Guo, Luo, Yu, Sha, Jiang, Luoying, Yin, Yanbo, Zhang, Jiajia, Chen, Bing, Wang, Wuqing, Chai, Renjie, Chen, Zheng-Yi, Li, Huawei, Shu, Yilai

“…Autosomal recessive deafness 9, caused by mutations of the OTOF gene, is characterised by congenital or prelingual, severe-to-complete, bilateral hearing loss…”
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Unveiling a novel GJB2 dominant K22T mutation in a Chinese family with hearing loss by Ji, Haiting, Shu, Yilai, Li, Huawei

“…Hearing loss constitutes one of the most prevalent conditions within the field of otolaryngology. Recent investigations have revealed that mutations in…”
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Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism by Tang, Yuefeng, Wallace, Martina, Sanchez-Gurmaches, Joan, Hsiao, Wen-Yu, Li, Huawei, Lee, Peter L., Vernia, Santiago, Metallo, Christian M., Guertin, David A.

“…Adipose tissue de novo lipogenesis (DNL) positively influences insulin sensitivity, is reduced in obesity, and predicts insulin resistance. Therefore,…”
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Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor by Xiao, Qingquan, Xu, Zhijiao, Xue, Yuanyuan, Xu, Chunlong, Han, Lei, Liu, Yuanhua, Wang, Fang, Zhang, Runze, Han, Shuang, Wang, Xing, Li, Geng-Lin, Li, Huawei, Yang, Hui, Shu, Yilai

“…Programmable RNA editing tools enable the reversible correction of mutant transcripts, reducing the potential risk associated with permanent genetic changes…”
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Exploring socioeconomic and environmental coordination in the Yangtze River Delta Region using a game theory stepwise-cluster factorial coupling coordination model by Sun, Jie, Xu, Mengjia, Suo, Cai, Yang, Yue, Li, Huawei, Liu, Dong

“…Economic growth has brought about escalating environmental challenges. The purist of socioeconomic and environmental coordination necessitates a deep…”
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Renewed proliferation in adult mouse cochlea and regeneration of hair cells by Shu, Yilai, Li, Wenyan, Huang, Mingqian, Quan, Yi-Zhou, Scheffer, Deborah, Tian, Chunjie, Tao, Yong, Liu, Xuezhong, Hochedlinger, Konrad, Indzhykulian, Artur A., Wang, Zhengmin, Li, Huawei, Chen, Zheng-Yi

“…The adult mammalian inner ear lacks the capacity to divide or regenerate. Damage to inner ear generally leads to permanent hearing loss in humans. Here, we…”
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The therapeutic use of exosomes in children with adenoid hypertrophy accompanied by otitis media with effusion (AHOME): a protocol study by Liu, Yixuan, Lu, Xiaoling, Sun, Shan, Yu, Huiqian, Li, Huawei

“…The adenoids act as a reservoir of bacterial pathogens and immune molecules, and they are significantly involved in children with otitis media with effusion…”
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