Search Results - "Li, Houkai"

The Role of Gut Microbiota in Atherosclerosis and Hypertension by Ma, Junli, Li, Houkai

“…In recent years, accumulating evidence has indicated the importance of gut microbiota in maintaining human health. Gut dysbiosis is associated with the…”
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Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy by Ma, Junli, Zhou, Qihang, Li, Houkai

“…The gut microbiota plays critical roles in development of obese-related metabolic diseases such as nonalcoholic fatty liver disease (NAFLD), type 2…”
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Akkermansia muciniphila: is it the Holy Grail for ameliorating metabolic diseases? by Yan, Juan, Sheng, Lili, Li, Houkai

“…The increasing prevalence of metabolic diseases has become a severe public health problem. Gut microbiota play important roles in maintaining human health by…”
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Application of metabolomics for unveiling the therapeutic role of traditional Chinese medicine in metabolic diseases by Wu, Gaosong, Zhang, Weidong, Li, Houkai

“…Traditional medicine has been practiced for thousands of years in China and some Asian countries. Traditional Chinese Medicine (TCM) is characterized as…”
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Novel Applications of Metabolomics in Personalized Medicine: A Mini-Review by Li, Bingbing, He, Xuyun, Jia, Wei, Li, Houkai

“…Interindividual variability in drug responses and disease susceptibility is common in the clinic. Currently, personalized medicine is highly valued, the idea…”
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Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism by Huang, Fengjie, Zheng, Xiaojiao, Ma, Xiaohui, Jiang, Runqiu, Zhou, Wangyi, Zhou, Shuiping, Zhang, Yunjing, Lei, Sha, Wang, Shouli, Kuang, Junliang, Han, Xiaolong, Wei, Meilin, You, Yijun, Li, Mengci, Li, Yitao, Liang, Dandan, Liu, Jiajian, Chen, Tianlu, Yan, Chao, Wei, Runmin, Rajani, Cynthia, Shen, Chengxing, Xie, Guoxiang, Bian, Zhaoxiang, Li, Houkai, Zhao, Aihua, Jia, Wei

“…Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant…”
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Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanism and Application of Metabolomics by He, Xuyun, Ji, Guang, Jia, Wei, Li, Houkai

“…Gut microbiota are intricately involved in the development of obesity-related metabolic diseases such as nonalcoholic fatty liver disease (NAFLD), type 2…”
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Desulfovibrio vulgaris, a potent acetic acid-producing bacterium, attenuates nonalcoholic fatty liver disease in mice by Hong, Ying, Sheng, Lili, Zhong, Jing, Tao, Xin, Zhu, Weize, Ma, Junli, Yan, Juan, Zhao, Aihua, Zheng, Xiaojiao, Wu, Gaosong, Li, Bingbing, Han, Bangxing, Ding, Kan, Zheng, Ningning, Jia, Wei, Li, Houkai

“…The emerging evidence supports the use of prebiotics like herb-derived polysaccharides for treating nonalcoholic fatty liver disease (NAFLD) by modulating gut…”
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Gut microbiota remodeling improves natural aging-related disorders through Akkermansia muciniphila and its derived acetic acid by Ma, Junli, Liu, Zekun, Gao, Xinxin, Bao, Yiyang, Hong, Ying, He, Xiaofang, Zhu, Weize, Li, Yan, Huang, Wenjin, Zheng, Ningning, Sheng, Lili, Zhou, Ben, Chen, Hongzhuan, Li, Houkai

“…Accumulating evidence indicates gut microbiota contributes to aging-related disorders. However, the exact mechanism underlying gut dysbiosis-related…”
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Gut microbiota: a potential new territory for drug targeting by Jia, Wei, Li, Houkai, Zhao, Liping, Nicholson, Jeremy K

“…The emerging influence of intestinal microorganisms on human health has led to the prospect of modulating gut microbiota composition as a novel therapeutic…”
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Integrated Metagenomic and Metabolomic Analyses of the Effect of Astragalus Polysaccharides on Alleviating High-Fat Diet–Induced Metabolic Disorders by Hong, Ying, Li, Bingbing, Zheng, Ningning, Wu, Gaosong, Ma, Junli, Tao, Xin, Chen, Linlin, Zhong, Jing, Sheng, Lili, Li, Houkai

“…Most herbal polysaccharides possess multiple benefits against metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD) and obesity. However, the…”
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Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways by Xiao, Fei, Huang, Zhiying, Li, Houkai, Yu, Junjie, Wang, Chunxia, Chen, Shanghai, Meng, Qingshu, Cheng, Ying, Gao, Xiang, Li, Jia, Liu, Yong, Guo, Feifan

“…We have previously shown that serum insulin levels decrease threefold and blood glucose levels remain normal in mice fed a leucine-deficient diet, suggesting…”
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A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential by YUNPING QIU, GUOXIANG CAI, WEITING GE, ZHANXIANG ZHOU, XU, Lisa X, WEIPING JIA, SHU ZHENG, YUN YEN, WEI JIA, BINGSEN ZHOU, DAN LI, AIHUA ZHAO, GUOXIANG XIE, HOUKAI LI, SANJUN CAI, DONG XIE, CHANGZHI HUANG

“…Metabolic phenotyping has provided important biomarker findings, which, unfortunately, are rarely replicated across different sample sets due to the variations…”
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Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose Tissue by Cheng, Ying, Meng, Qingshu, Wang, Chunxia, Li, Houkai, Huang, Zhiying, Chen, Shanghai, Xiao, Fei, Guo, Feifan

“…Leucine Deprivation Decreases Fat Mass by Stimulation of Lipolysis in White Adipose Tissue and Upregulation of Uncoupling Protein 1 (UCP1) in Brown Adipose…”
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Gut microbiota remodeling reverses aging-associated inflammation and dysregulation of systemic bile acid homeostasis in mice sex-specifically by Ma, Junli, Hong, Ying, Zheng, Ningning, Xie, Guoxiang, Lyu, Yuanzhi, Gu, Yu, Xi, Chuchu, Chen, Linlin, Wu, Gaosong, Li, Yue, Tao, Xin, Zhong, Jing, Huang, Zhenzhen, Wu, Wenbin, Yuan, Lin, Lin, Min, Lu, Xiong, Zhang, Weidong, Jia, Wei, Sheng, Lili, Li, Houkai

“…Aging is usually characterized with inflammation and disordered bile acids (BAs) homeostasis, as well as gut dysbiosis. The pathophysiological changes during…”
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Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling by Zhong, Jing, He, Xiaofang, Gao, Xinxin, Liu, Qiaohong, Zhao, Yu, Hong, Ying, Zhu, Weize, Yan, Juan, Li, Yifan, Li, Yan, Zheng, Ningning, Bao, Yiyang, Wang, Hao, Ma, Junli, Huang, Wenjin, Liu, Zekun, Lyu, Yuanzhi, Ke, Xisong, Jia, Wei, Xie, Cen, Hu, Yiyang, Sheng, Lili, Li, Houkai

“…Nonalcoholic fatty liver disease (NAFLD) is usually characterized with disrupted bile acid (BA) homeostasis. However, the exact role of certain BA in NAFLD is…”
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Divergent impacts on the gut microbiome and host metabolism induced by traditional Chinese Medicine with Cold or Hot properties in mice by Li, Bingbing, Tao, Xin, Sheng, Lili, Li, Yan, Zheng, Ningning, Li, Houkai

“…Traditional Chinese Medicine (TCM) has been practiced and developed in China over thousands of years under the guidance of a series of complicated traditional…”
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Paeonol attenuates high-fat-diet-induced atherosclerosis in rabbits by anti-inflammatory activity by Li, Houkai, Dai, Min, Jia, Wei

“…Cortex Moutan (Paeonia suffruticosa Andrews, Ranunculaceae) has several uses in traditional medicine, such as analgesic, antipyretic, and anti-inflammatory…”
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Gut microbiota-brain bile acid axis orchestrates aging-related neuroinflammation and behavior impairment in mice by Ma, Junli, Li, Mingxiao, Bao, Yiyang, Huang, Wenjin, He, Xiaofang, Hong, Ying, Wei, Wenjing, Liu, Zekun, Gao, Xinxin, Yang, Yang, Cui, Zhengyu, Wang, Wantao, Wang, Jie, Zhu, Weize, Zheng, Ningning, Pan, Lingyun, Wang, Deheng, Ke, Zunji, Zhou, Ben, Sheng, Lili, Li, Houkai

“…Emerging evidence shows that disrupted gut microbiota-bile acid (BA) axis is critically involved in the development of neurodegenerative diseases. However, the…”
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Variations of Gut Microbiome Profile Under Different Storage Conditions and Preservation Periods: A Multi-Dimensional Evaluation by Ma, Junli, Sheng, Lili, Hong, Ying, Xi, Chuchu, Gu, Yu, Zheng, Ningning, Li, Mengci, Chen, Linlin, Wu, Gaosong, Li, Yue, Yan, Juan, Han, Ruiting, Li, Bingbing, Qiu, Huihui, Zhong, Jing, Jia, Wei, Li, Houkai

“…Gut dysbiosis is heavily involved in the development of various human diseases. There are thousands of publications per year for investigating the role of gut…”
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