Search Results - "Li, Hanping"
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A unified classification system for HIV-1 5' long terminal repeats
Published in PloS one (02-05-2024)“…The HIV-1 provirus mainly consists of internal coding region flanked by 1 long terminal repeats (LTRs) at each terminus. The LTRs play important roles in HIV-1…”
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Identification of a novel HIV-1 second-generation Circulating Recombinant Form CRF109_0107 in China
Published in The Journal of infection (01-11-2020)Get full text
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A genome-wide association study on lipoprotein (a) levels and coronary artery disease severity in a Chinese population
Published in Journal of lipid research (01-08-2019)“…Lipoprotein (a) [Lp(a)] is a genetically determined risk factor of coronary artery disease (CAD). Previous genome-wide association studies (GWASs), which were…”
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Different Profiles of Antibodies and Cytokines Were Found Between Severe and Moderate COVID-19 Patients
Published in Frontiers in immunology (19-08-2021)“…Objectives Our objective was to determine the antibody and cytokine profiles in different COVID-19 patients. Methods COVID-19 patients with different clinical…”
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Endogenous Retrovirus Elements Are Co-Expressed with IFN Stimulation Genes in the JAK-STAT Pathway
Published in Viruses (24-12-2022)“…: Endogenous retrovirus (ERV) elements can act as proximal regulatory elements in promoting interferon (IFN) responses. Previous relevant studies have mainly…”
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Establishment and application of a method of tagged-amplicon deep sequencing for low-abundance drug resistance in HIV-1
Published in Frontiers in microbiology (22-08-2022)“…In the latest HIV-1 global drug resistance report released by WHO, countries are advised to strengthen pre-treatment monitoring of drug resistance in AIDS…”
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Identification of differentially expressed HERV-K(HML-2) loci in colorectal cancer
Published in Frontiers in microbiology (05-06-2023)“…Colorectal cancer is one of the malignant tumors with the highest mortality rate in the world. Survival rates vary significantly among patients at various…”
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Natural presence of the V179D and K103R/V179D mutations associated with resistance to nonnucleoside reverse transcriptase inhibitors in HIV-1 CRF65_cpx strains
Published in BMC infectious diseases (28-04-2020)“…There is increasing evidence that HIV-1 genetic diversity can have an impact on drug resistance. The aim of this study is to investigate the epidemiological…”
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Comprehensive Identification and Characterization of HML-9 Group in Chimpanzee Genome
Published in Viruses (01-06-2024)“…Endogenous retroviruses (ERVs) are related to long terminal repeat (LTR) retrotransposons, comprising gene sequences of exogenous retroviruses integrated into…”
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High Expression of HERV-K (HML-2) Might Stimulate Interferon in COVID-19 Patients
Published in Viruses (07-05-2022)“…Interferon is a marker of host antiviral immunity, which is disordered in COVID-19 patients. ERV can affect the secretion of interferon through the cGAS-STING…”
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Comprehensive identification and characterization of the HERV-K (HML-9) group in the human genome
Published in Retrovirology (08-06-2022)“…Human endogenous retroviruses (HERVs) result from ancestral infections caused by exogenous retroviruses that became incorporated into the germline DNA and…”
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Infection by Diverse HIV-1 Subtypes Leads to Different Elevations in HERV-K Transcriptional Levels in Human T Cell Lines
Published in Frontiers in microbiology (17-05-2021)“…Human endogenous retroviruses (HERVs) make up ~8% of the human genome, and for millions of years, they have been subject to strict biological regulation. Many…”
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Genetic characterization of HIV-1 epidemic in Anhui Province, China
Published in Virology journal (03-02-2020)“…Anhui Province in China is facing a severe HIV epidemic with an increasing number of newly diagnosed cases. In this study, HIV genetic characteristics in the…”
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Significant Upregulation of HERV-K (HML-2) Transcription Levels in Human Lung Cancer and Cancer Cells
Published in Frontiers in microbiology (10-03-2022)“…Lung cancer is the second most common cancer worldwide and the leading cause of cancer death in the world. Therefore, there is an urgent need to develop new…”
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Comprehensive characterization of ERV-K (HML-8) in the chimpanzee genome revealed less genomic activity than humans
Published in Frontiers in cellular and infection microbiology (22-02-2024)“…Endogenous retroviruses (ERVs) originate from ancestral germline infections caused by exogenous retroviruses. Throughout evolution, they have become fixed…”
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Limited nucleotide changes of HIV-1 subtype B Rev response element in China affect overall Rev-RRE activity and viral replication
Published in Frontiers in microbiology (12-12-2022)“…The HIV-1 Rev response element (RRE) is a cis-acting RNA element that facilitates the nuclear export of mRNA-containing introns by binding specifically to the…”
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Human Endogenous Retroviruses and Hematological Malignant Tumors
Published in Infectious microbes & diseases (01-06-2022)“…Abstract Human endogenous retrovirus (HERV) gene sequences are remnants of retroviruses that infected the ancestors of humans millions of years ago and were…”
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Phylogenetic analysis highlights the role of older people in the transmission of HIV-1 in Fuyang, Anhui Province, China
Published in BMC infectious diseases (27-06-2019)“…The proportion of older HIV-1 infected people in China has increased rapidly in recent years. Elucidation of the transmission characteristics of this high-risk…”
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Phylodynamics of major CRF01_AE epidemic clusters circulating in mainland of China
Published in Scientific reports (24-07-2017)“…As the most dominant HIV-1 strain in China, CRF01_AE needs to have its evolutionary and demographic history documented. In this study, we provide phylogenetic…”
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p53 Binding Sites in Long Terminal Repeat 5Hs (LTR5Hs) of Human Endogenous Retrovirus K Family (HML-2 Subgroup) Play Important Roles in the Regulation of LTR5Hs Transcriptional Activity
Published in Microbiology spectrum (31-08-2022)“…The long terminal repeats (LTRs) of human endogenous retroviruses (HERVs) are distributed throughout the human genome and provide favorable conditions to…”
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