Search Results - "Li, H. W."

Drug Discovery and Natural Products: End of an Era or an Endless Frontier? by Li, Jesse W.-H, Vederas, John C

“…Historically, the majority of new drugs have been generated from natural products (secondary metabolites) and from compounds derived from natural products…”
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Enzymatic Synthesis of Resorcylic Acid Lactones by Cooperation of Fungal Iterative Polyketide Synthases Involved in Hypothemycin Biosynthesis by Zhou, Hui, Qiao, Kangjian, Gao, Zhizeng, Meehan, Michael J, Li, Jesse W.-H, Zhao, Xiling, Dorrestein, Pieter C, Vederas, John C, Tang, Yi

“…Hypothemycin is a macrolide protein kinase inhibitor from the fungus Hypomyces subiculosus. During biosynthesis, its carbon framework is assembled by two…”
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Aerosol source plume physical characteristics from space-based multiangle imaging by Kahn, Ralph A., Li, W.-H., Moroney, Catherine, Diner, David J., Martonchik, John V., Fishbein, Evan

“…Models that assess aerosol effects on regional air quality and global climate parameterize aerosol sources in terms of amount, type, and injection height. The…”
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Observational studies of the meteorological characteristics associated with poor air quality over the Pearl River Delta in China by Wu, M, Wu, D, Fan, Q, Wang, B. M, Li, H. W, Fan, S. J

“…The structure of the atmospheric boundary layer (ABL) and its influence on regional air quality over the Pearl River Delta (PRD) were examined through two…”
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Viscoelastic properties of MR elastomers under harmonic loading by Li, W. H., Zhou, Y., Tian, T. F.

“…This paper presents both experimental and modeling studies of viscoelastic properties of MR elastomers under harmonic loadings. Magnetorheological elastomer…”
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Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase by Ma, Suzanne M, Li, Jesse W.-H, Choi, Jin W, Zhou, Hui, Lee, K.K. Michael, Moorthie, Vijayalakshmi A, Xie, Xinkai, Kealey, James T, Da Silva, Nancy A, Vederas, John C, Tang, Yi

“…Highly reducing iterative polyketide synthases are large, multifunctional enzymes that make important metabolites in fungi, such as lovastatin, a…”
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Dewetting of conducting polymer inkjet droplets on patterned surfaces by Sirringhaus, H, Wang, J. Z, Zheng, Z. H, Li, H. W, Huck, W. T. S

“…The manufacture of high-performance electronic devices with micrometre or even submicrometre dimensions by solution processing and direct printing, requires…”
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Measuring luteinising hormone pulsatility with a robotic aptamer-enabled electrochemical reader by Liang, Shaolin, Kinghorn, Andrew B., Voliotis, Margaritis, Prague, Julia K., Veldhuis, Johannes D., Tsaneva-Atanasova, Krasimira, McArdle, Craig A., Li, Raymond H. W., Cass, Anthony E. G., Dhillo, Waljit S., Tanner, Julian A.

“…Normal reproductive functioning is critically dependent on pulsatile secretion of luteinising hormone (LH). Assessment of LH pulsatility is important for the…”
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Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans by Ding, S. W, Lu, R, Maduro, M, Li, F, Li, H. W, Broitman-Maduro, G, Li, W. X

“…The worm Caenorhabditis elegans is a model system for studying many aspects of biology, including host responses to bacterial pathogens, but it is not known to…”
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Materials designing of metal borohydrides: Viewpoints from thermodynamical stabilities by Li, H.-W., Orimo, S., Nakamori, Y., Miwa, K., Ohba, N., Towata, S., Züttel, A.

“…Double-cation borohydrides MLi m− n (BH 4) m (M = Zn, n = 2; M = Al, n = 3; M = Zr, n = 4; n ≤ m) were expected to be synthesized and their thermodynamical…”
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Dehydriding and rehydriding processes of well-crystallized Mg(BH 4) 2 accompanying with formation of intermediate compounds by Li, H.-W., Kikuchi, K., Nakamori, Y., Ohba, N., Miwa, K., Towata, S., Orimo, S.

“…Dehydriding and rehydriding properties of well-crystallized Mg(BH 4) 2 were systematically investigated by thermogravimetry (TG) and…”
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In situ forming LiF nanodecorated electrolyte/electrode interfaces for stable all-solid-state batteries by Shi, X., Pang, Y., Wang, B., Sun, H., Wang, X., Li, Y., Yang, J., Li, H.-W., Zheng, S.

“…The unstable solid electrolyte/electrode interface with dendrite growth and resistance increase significantly reduces the safety and efficiency of…”
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Exposure to fine particulate matter associated with senile lentigo in Chinese women: a cross‐sectional study by Peng, F., Xue, C.‐H., Hwang, S.K., Li, W.‐H., Chen, Z., Zhang, J.‐Z.

“…Background Skin ageing especially senile lentigo directly affects self‐esteem. For decades, senile lentigo has been associated with chronic exposure to solar…”
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CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation by Zabrady, Katerina, Zabrady, Matej, Kolesar, Peter, Li, Arthur W. H., Doherty, Aidan J.

“…CRISPR-Cas pathways provide prokaryotes with acquired “immunity” against foreign genetic elements, including phages and plasmids. Although many of the proteins…”
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Reference-frame-independent quantum-key-distribution server with a telecom tether for an on-chip client by Zhang, P, Aungskunsiri, K, Martín-López, E, Wabnig, J, Lobino, M, Nock, R W, Munns, J, Bonneau, D, Jiang, P, Li, H W, Laing, A, Rarity, J G, Niskanen, A O, Thompson, M G, O'Brien, J L

“…We demonstrate a client-server quantum key distribution (QKD) scheme. Large resources such as laser and detectors are situated at the server side, which is…”
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Thermodynamical stabilities of metal-borohydrides by Nakamori, Y., Li, H.-W., Kikuchi, K., Aoki, M., Miwa, K., Towata, S., Orimo, S.

“…Metal-borohydrides M(BH 4) n (M = Ca, Sc, Ti, V, Cr, Mn, Zn (fourth period in periodic table) and Al; n = 2–4) were synthesized by a mechanical milling process…”
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A blackberry–dill extract combination synergistically increases skin elasticity by Meza, D., Li, W.‐H., Seo, I., Parsa, R., Kaur, S., Kizoulis, M., Southall, M.D.

“…Background The loss of structural elastin due to intrinsic and extrinsic ageing results in the skin’s inability to stretch and recoil (decrease in elasticity)…”
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Crystal structure and biochemical studies of the trans-acting polyketide enoyl reductase LovC from lovastatin biosynthesis by Ames, Brian D, Nguyen, Chi, Bruegger, Joel, Smith, Peter, Xu, Wei, Ma, Suzanne, Wong, Emily, Wong, Steven, Xie, Xinkai, Li, Jesse W.-H, Vederas, John C, Tang, Yi, Tsai, Shiou-Chuan

“…Lovastatin is an important statin prescribed for the treatment and prevention of cardiovascular diseases. Biosynthesis of lovastatin uses an iterative type I…”
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Development of a diagnostic model for pre-washout screening of primary aldosteronism by Wang, Q., Dong, H., LI, H.-W., Zheng, Z.-H., Liu, Y.-Z., Hua, Y.-H., Xiong, Y.-J., Zhang, H.-M., Song, L., Zou, Y.-B., Jiang, X.-J.

“…Purpose Primary aldosteronism (PA) diagnosis is affected by antihypertensive drugs that are commonly taken by patients with suspected PA. In this study, we…”
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Relationships between resilience and quality of life in parents of children with cancer by Luo, Y. H., Li, W. H. C., Cheung, A. T., Ho, L. L. K., Xia, W., He, X. L., Zhang, J. P., Chung, J. O. K.

“…A child suffering from cancer can be considerably stressful for parents, exerting a negative impact on their psychological well-being and quality of life. This…”
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