Search Results - "Li, Fuxi"

Compositional alterations of gut microbiota in nonalcoholic fatty liver disease patients: a systematic review and Meta-analysis by Li, Fuxi, Ye, Junzhao, Shao, Congxiang, Zhong, Bihui

“…Although imbalanced intestinal flora contributes to the pathogenesis of nonalcoholic fatty liver disease (NAFLD), conflicting results have been obtained for…”
Get full text

Comprehensive 3D epigenomic maps define limbal stem/progenitor cell function and identity by Li, Mingsen, Huang, Huaxing, Wang, Bofeng, Jiang, Shaoshuai, Guo, Huizhen, Zhu, Liqiong, Wu, Siqi, Liu, Jiafeng, Wang, Li, Lan, Xihong, Zhang, Wang, Zhu, Jin, Li, Fuxi, Tan, Jieying, Mao, Zhen, Liu, Chunqiao, Ji, Jianping, Ding, Junjun, Zhang, Kang, Yuan, Jin, Liu, Yizhi, Ouyang, Hong

“…The insights into how genome topology couples with epigenetic states to govern the function and identity of the corneal epithelium are poorly understood. Here,…”
Get full text

A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation by Yi, Yang, Li, Yanqiang, Meng, Qingshu, Li, Qiaqia, Li, Fuxi, Lu, Bing, Shen, Jiangchuan, Fazli, Ladan, Zhao, Dongyu, Li, Chao, Jiang, Weihua, Wang, Rui, Liu, Qipeng, Szczepanski, Aileen, Li, Qianru, Qin, Wei, Weiner, Adam B., Lotan, Tamara L., Ji, Zhe, Kalantry, Sundeep, Wang, Lu, Schaeffer, Edward M., Niu, Hengyao, Dong, Xuesen, Zhao, Wei, Chen, Kaifu, Cao, Qi

“…Dysregulated translation is a common feature of cancer. Uncovering its governing factors and underlying mechanism are important for cancer therapy. Here, we…”
Get full text

H3K27me3 loss plays a vital role in CEMIP mediated carcinogenesis and progression of breast cancer with poor prognosis by Hsieh, I-yun, He, Jincan, Wang, Li, Lin, Bo, Liang, Zhen, Lu, Bing, Chen, Weixin, Lu, Guohao, Li, Fuxi, Lv, Weiming, Zhao, Wei, Li, Jie

“…H3K27me3 modification inactivates gene transcription by resulting in condensed chromatin. However, the landscape and biological functions of H3K27me3 in breast…”
Get full text

Interplay of m6A and histone modifications contributes to temozolomide resistance in glioblastoma by Li, Fuxi, Chen, Siyun, Yu, Jiaming, Gao, Zhuoxing, Sun, Zhangyi, Yi, Yang, Long, Teng, Zhang, Chuanxia, Li, Yuzhe, Pan, Yimin, Qin, Chaoying, Long, Wenyong, Liu, Qing, Zhao, Wei

“…Background Despite the development of new treatment protocols for glioblastoma (GBM), temozolomide (TMZ) resistance remains a primary hindrance. Previous…”
Get full text

Generating an MEIS1 homozygous knockout human embryonic stem cell line using the CRISPR/Cas9 system by Zhang, Canwei, Yu, Yankun, Li, Fuxi, Lan, Xihong, Wang, Li

“…Myeloid ecotropic viral integration site 1 (MEIS1) plays an essential role in the development of several embryonic organs, such as the central nervous system…”
Get full text

Varied Relationship of Lipid and Lipoprotein Profiles to Liver Fat Content in Phenotypes of Metabolic Associated Fatty Liver Disease by Wu, Tingfeng, Ye, Junzhao, Shao, Congxiang, Li, Fuxi, Lin, Yansong, Ma, Qianqian, Wang, Wei, Feng, Shiting, Zhong, Bihui

“…Progressive overloads of intrahepatic triglycerides are related to metabolic dysregulation of multiple lipid and lipoprotein profiles, but whether similar dose…”
Get full text

Effect of orlistat on liver fat content in patients with nonalcoholic fatty liver disease with obesity: assessment using magnetic resonance imaging-derived proton density fat fraction by Ye, Junzhao, Wu, Yanqin, Li, Fuxi, Wu, Tingfeng, Shao, Congxiang, Lin, Yansong, Wang, Wei, Feng, Shiting, Zhong, Bihui

“…Background: The liver effect of orlistat as a weight control treatment in patients with nonalcoholic fatty liver disease (NAFLD) with obesity remains…”
Get full text

Distinct Dose-Dependent Association of Free Fatty Acids with Diabetes Development in Nonalcoholic Fatty Liver Disease Patients by Li, Fuxi, Ye, Junzhao, Sun, Yanhong, Lin, Yansong, Wu, Tingfeng, Shao, Congxiang, Ma, Qianqian, Liao, Xianhua, Feng, Shiting, Zhong, Bihui

“…Excessive delivery of free fatty acids (FFAs) to the liver promotes steatosis and insulin resistance (IR), with IR defined as reduced glucose uptake, glycogen…”
Get full text

Steatosis grading consistency between controlled attenuation parameter and MRI-PDFF in monitoring metabolic associated fatty liver disease by Shao, Cong xiang, Ye, Junzhao, Dong, Zhi, Li, Fuxi, Lin, Yansong, Liao, Bing, Feng, Shiting, Zhong, Bihui

“…Background: The consistency in steatosis grading between magnetic resonance imaging-based proton density fat fraction (MRI-PDFF) and controlled attenuation…”
Get full text

Targeting Super‐Enhancers via Nanoparticle‐Facilitated BRD4 and CDK7 Inhibitors Synergistically Suppresses Pancreatic Ductal Adenocarcinoma by Huang, Chen‐Song, You, Xinru, Dai, Chunlei, Xu, Qiong‐Cong, Li, Fuxi, Wang, Li, Huang, Xi‐Tai, Wang, Jie‐Qin, Li, Shi‐Jin, Gao, Zhuoxing, Wu, Jun, Yin, Xiao‐Yu, Zhao, Wei

“…Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignant cancer with complex genomic variations, and no targetable genomic lesions have been found yet…”
Get full text

Insulin resistance exhibits varied metabolic abnormalities in nonalcoholic fatty liver disease, chronic hepatitis B and the combination of the two: a cross-sectional study by Ye, Junzhao, Hu, Xuan, Wu, Tingfeng, Wu, Yanqin, Shao, Congxiang, Li, Fuxi, Lin, Yansong, Feng, Shiting, Wang, Wei, Zhong, Bihui

“…Insulin resistance (IR) related metabolic disorders are associated with a worse prognosis of chronic hepatitis B virus (CHB) infection or nonalcoholic fatty…”
Get full text

Distinct Cause of Death Profiles of Hospitalized Non-alcoholic Fatty Liver Disease: A 10 Years' Cross-Sectional Multicenter Study in China by Lin, Yansong, Gong, Xiaorong, Li, Xin, Shao, Congxiang, Wu, Tingfeng, Li, Minrui, Li, Fuxi, Ma, Qianqian, Ye, Junzhao, Zhong, Bihui

“…The clinical burden and natural history of non-alcoholic fatty liver disease (NAFLD) vary globally. We aimed to investigate NAFLD-related mortality profiles in…”
Get full text

Electrospun film composed of pearl-string-like microfibers exhibiting excellent radiative cooling performance, moisture permeability and self-cleaning function by Li, Fuxi, Liu, Mingrao, Wu, Daxiong, Zhang, Canying, Zhu, Haitao

“…The double threat of extremely hot summer and the pandemic of Covid-19 makes it important to develop protective clothing with remarkable advantage of personal…”
Get full text

Mo1491 DISTINCT DOSE-RESPONSE EFFECTS OF FREE FATTY ACIDS ON INSULIN RESISTANCE, PREDIABETES, AND DIABETES IN NONALCOHOLIC FATTY LIVER DISEASE by Li, Fuxi, Ye, Junzhao, Zhong, Bihui

Get full text

N 6 -Methyladenosine Modulates Nonsense-Mediated mRNA Decay in Human Glioblastoma by Li, Fuxi, Yi, Yang, Miao, Yanyan, Long, Wenyong, Long, Teng, Chen, Siyun, Cheng, Weisheng, Zou, Changye, Zheng, Yueyuan, Wu, Xingui, Ding, Junjun, Zhu, Kaiyu, Chen, Delin, Xu, Qiongcong, Wang, Jinkai, Liu, Qing, Zhi, Feng, Ren, Jian, Cao, Qi, Zhao, Wei

“…The N -methyladenosine (m A) modification influences various mRNA metabolic events and tumorigenesis, however, its functions in nonsense-mediated mRNA decay…”
Get full text

METTL3-mediated N6-methyladenosine modification of DUSP5 mRNA promotes gallbladder-cancer progression by Chen, Hua-Dong, Li, Fuxi, Chen, Siyun, Zhong, Zhi-Hai, Gao, Peng-Fei, Gao, Wen-Zong

“…N 6 -methyladenosine (m 6 A) RNA methylation and its associated methyltransferase METTL3 play an important role in tumorigenesis of a series of tumors…”
Get full text

Different predictors of steatosis and fibrosis severity among lean, overweight and obese patients with nonalcoholic fatty liver disease by Shao, Congxiang, Ye, Junzhao, Li, Fuxi, Feng, Shiting, Wang, Wei, Zhong, Bihui

“…Non-obese nonalcoholic fatty liver disease (NAFLD) is paradoxically associated with improved metabolic and pathological features at diagnosis but worse…”
Get full text

IGF2BP2 Maintains Retinal Pigment Epithelium Homeostasis by Stabilizing PAX6 and OTX2 by Wu, Siqi, Li, Fuxi, Mo, Kunlun, Huang, Huaxing, Yu, Yankun, Huang, Ying, Liu, Jiafeng, Li, Mingsen, Tan, Jieying, Lin, Zesong, Han, Zhuo, Wang, Li, Ouyang, Hong

“…N6-methyladenosine (m6A) methylation is a chemical modification that occurs on RNA molecules, where the hydrogen atom of adenine (A) nucleotides is replaced by…”
Get full text

Early Predictors of Cardiovascular Disease Risk in Nonalcoholic Fatty Liver Disease: Non-obese Versus Obese Patients by Shao, Congxiang, Ye, Junzhao, Li, Fuxi, Lin, Yansong, Wu, Tingfeng, Wang, Wei, Feng, Shiting, Zhong, Bihui

“…Background Nonalcoholic fatty liver disease (NAFLD) is regarded as a risk factor of cardiovascular disease (CVD). However, the association between non-obese…”
Get full text