Search Results - "Li, Fenge"
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Exploiting Tumor Neoantigens to Target Cancer Evolution: Current Challenges and Promising Therapeutic Approaches
Published in Cancer discovery (01-05-2021)“…Immunotherapeutic manipulation of the antitumor immune response offers an attractive strategy to target genomic instability in cancer. A subset of…”
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2
Distinct distribution patterns of prokaryotes between sediment and water in the Yellow River estuary
Published in Applied microbiology and biotechnology (01-11-2016)“…There are close exchanges between sediment and water in estuaries; however, the patterns of prokaryotic community assembly in these two habitat types are still…”
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3
Microglia in the developing retina
Published in Neural development (30-12-2019)“…Microglia are increasingly shown to be key players in neuron development and synapse connectivity. However, the underlying mechanisms by which microglia…”
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4
The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss
Published in Nature immunology (01-05-2012)“…Periodontitis is associated with aging and more neutrophil-mediated tissue pathology. Hajishengallis and colleagues show an inverse correlation between…”
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Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers
Published in Nature communications (21-10-2020)“…Cytotoxic T lymphocyte (CTL)-based cancer immunotherapies have shown great promise for inducing clinical regressions by targeting tumor-associated antigens…”
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Diagnosis of mycobacterium avium complex infection utilizing metagenomics next-generation sequencing: a case report
Published in Frontiers in medicine (18-10-2023)“…Mycobacterium avium-intracellulare complex (MAC) is a type of nontuberculous mycobacteria (NTM) and is associated with underlying pulmonary diseases, such as…”
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7
The oncogenic microRNA miR-21 promotes regulated necrosis in mice
Published in Nature communications (20-05-2015)“…MicroRNAs (miRNAs) regulate apoptosis, yet their role in regulated necrosis remains unknown. miR-21 is overexpressed in nearly all human cancer types and its…”
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miR-762 promotes porcine immature Sertoli cell growth via the ring finger protein 4 (RNF4) gene
Published in Scientific reports (06-09-2016)“…A growing number of reports have revealed that microRNAs (miRNAs) play critical roles in spermatogenesis. Our previous study showed that miR-762 is…”
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The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss
Published in The Journal of immunology (1950) (15-01-2011)“…The C5a anaphylatoxin receptor (C5aR; CD88) is activated as part of the complement cascade and exerts important inflammatory, antimicrobial, and regulatory…”
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10
C1q Regulates Horizontal Cell Neurite Confinement in the Outer Retina
Published in Frontiers in neural circuits (16-10-2020)“…During development, neurons generate excess processes which are then eliminated in concert with circuit maturation. C1q is the initiating protein in the…”
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Association of tumor mutation burden and epidermal growth factor receptor inhibitor history with survival in patients with metastatic stage III/IV non-small-cell lung cancer: A retrospective study
Published in Clinics (São Paulo, Brazil) (01-01-2021)“…Lung cancer is the leading cause of cancer-related deaths worldwide. However, factors associated with the survival of patients with advanced non-small-cell…”
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A Retrospective Study on Using a Novel Single Needle Cone Puncture Approach for the Iodine-125 Seed Brachytherapy in Treating Patients With Thoracic Malignancy
Published in Frontiers in oncology (31-05-2021)“…Patients with progressive thoracic malignancy characterized by large irregular tumors with necrosis and life-threatening symptoms lack effective treatments. We…”
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miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor
Published in Scientific reports (14-06-2016)“…Labor is initiated as a result of hormonal changes that are induced by the activation of the inflammatory response and a series of biochemical events. The…”
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miR-135a Suppresses Granulosa Cell Growth by Targeting Tgfbr1 and Ccnd2 during Folliculogenesis in Mice
Published in Cells (Basel, Switzerland) (17-08-2021)“…The success of female reproduction relies on high quality oocytes, which is determined by well-organized cooperation between granulosa cells (GCs) and oocytes…”
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Evolution of CD8+ T Cell Receptor (TCR) Engineered Therapies for the Treatment of Cancer
Published in Cells (Basel, Switzerland) (10-09-2021)“…Engineered T cell receptor T (TCR-T) cell therapy has facilitated the generation of increasingly reliable tumor antigen-specific adaptable cellular products…”
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The Cervicovaginal Expression Level of Interleukin-6 Can be a Prediction Factor for Cervical Intraepithelial Neoplasias and Cervical Cancer: A Prospective Cohort Study
Published in Clinical and experimental obstetrics & gynecology (01-11-2023)“…Background: The aim of this prospective study was to investigate the expression of interleukin-6 (IL-6) of cervicovaginal washings in cervical intraepithelial…”
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Prognostic significance of peripheral and tumor-infiltrating lymphocytes in newly diagnosed stage III/IV non-small-cell lung cancer
Published in Frontiers in medicine (22-05-2024)“…Lymphocytes are effector cells that fight cancer by killing tumor cells. Here, we aim to explore the prognostic significance of both peripheral and…”
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Microarray-based approach identifies differentially expressed microRNAs in porcine sexually immature and mature testes
Published in PloS one (18-08-2010)“…MicroRNAs (miRNAs) are short non-coding RNA molecules which are proved to be involved in mammalian spermatogenesis. Their expression and function in the…”
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Identification of genome-wide copy number variations among diverse pig breeds by array CGH
Published in BMC genomics (24-12-2012)“…Recent studies have shown that copy number variation (CNV) in mammalian genomes contributes to phenotypic diversity, including health and disease status. In…”
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ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1
Published in Cell & bioscience (11-05-2023)“…ISGylation is a post-translational protein modification that regulates many life activities, including immunomodulation, antiviral responses, and embryo…”
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