Search Results - "Li, Endan"

Human-to-mouse prion-like propagation of mutant huntingtin protein by Jeon, Iksoo, Cicchetti, Francesca, Cisbani, Giulia, Lee, Suji, Li, Endan, Bae, Jiwoo, Lee, Nayeon, Li, Ling, Im, Wooseok, Kim, Manho, Kim, Hyun Sook, Oh, Seung-Hun, Kim, Tae-Aug, Ko, Jung Jae, Aubé, Benoit, Oueslati, Abid, Kim, Yun Joong, Song, Jihwan

“…Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder of the central nervous system (CNS) that is defined by a CAG expansion in exon 1…”
Get full text

Ghrelin directly stimulates adult hippocampal neurogenesis: implications for learning and memory by Li, Endan, Chung, Hyunju, Kim, Yumi, Kim, Dong Hyun, Ryu, Jong Hoon, Sato, Takahiro, Kojima, Masayasu, Park, Seungjoon

“…Adult hippocampal neurogenesis is important in mediating hippocampal-dependent learning and memory. Exogenous ghrelin is known to stimulate progenitor cell…”
Get full text

Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells by Chung, Hyunju, Li, Endan, Kim, Yumi, Kim, Sehee, Park, Seungjoon

“…Ghrelin, an endogenous ligand for the GH secretagogue receptor (GHS-R) receptor 1a (GHS-R1a), has been implicated in several physiologic processes involving…”
Get full text

Ghrelin attenuates kainic acid-induced neuronal cell death in the mouse hippocampus by Lee, Jiyeon, Lim, Eunjin, Kim, Yumi, Li, Endan, Park, Seungjoon

“…Ghrelin is an endogenous ligand for GH secretagogue receptor type 1a (GHSR1a), and is produced and released mainly from the stomach. It has been recently…”
Get full text

Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3β pathways by Lim, Eunjin, Lee, Sungyoub, Li, Endan, Kim, Yumi, Park, Seungjoon

“…Excitotoxic degeneration of spinal cord motoneurons has been proposed as a pathogenic mechanism in amyotrophic lateral sclerosis (ALS). Recently, we have…”
Get full text

Ghrelin-induced hippocampal neurogenesis and enhancement of cognitive function are mediated independently of GH/IGF-1 axis: lessons from the spontaneous dwarf rats by Li, Endan, Kim, Yumi, Kim, Sehee, Park, Seungjoon

“…We recently have reported that ghrelin modulates adult hippocampal neurogenesis. However, there is a possibility that the action of ghrelin on hippocampal…”
Get full text

Ghrelin stimulates proliferation, migration and differentiation of neural progenitors from the subventricular zone in the adult mice by Li, Endan, Kim, Yumi, Kim, Sehee, Sato, Takahiro, Kojima, Masayasu, Park, Seungjoon

“…Ghrelin has been shown to regulate neurogenesis in the hippocampus. The aim of this study was to investigate the possible influence of ghrelin on cell…”
Get full text

Neural Transplants From Human Induced Pluripotent Stem Cells Rescue the Pathology and Behavioral Defects in a Rodent Model of Huntington’s Disease by Yoon, Yongwoo, Kim, Hyun Sook, Hong, Chang Pyo, Li, Endan, Jeon, Iksoo, Park, Hyun Jung, Lee, Nayeon, Pei, Zhong, Song, Jihwan

“…Huntington’s disease (HD) is a devastating, autosomal-dominant inheritance disorder with the progressive loss of medium spiny neurons (MSN) and…”
Get full text

Insulin-Like Growth Factor-1 Inhibits 6-Hydroxydopamine-Mediated Endoplasmic Reticulum Stress-Induced Apoptosis via Regulation of Heme Oxygenase-1 and Nrf2 Expression in PC12 Cells by Kim, Yumi, Li, Endan, Park, Seungjoon

“…ABSTRACT Endoplasmic reticulum (ER) stress and oxidative stress appear to play a critical role in the progression of Parkinson's disease (PD). Insulin-like…”
Get full text

Hippocampus-dependent spatial learning and memory are impaired in growth hormone-deficient spontaneous dwarf rats by Li, Endan, Kim, Dong Hyun, Cai, Mudan, Lee, Sungyoub, Kim, Yumi, Lim, Eunjin, Ryu, Jong Hoon, Unterman, Terry G, Park, Seungjoon

“…Growth hormone (GH)/insulin-like growth factor-I deficiencies are known to cause alterations in brain development resulting in impairment of cognitive…”
Get full text

Ghrelin Protects Spinal Cord Motoneurons Against Chronic Glutamate Excitotoxicity by Inhibiting Microglial Activation by Lee, Sungyoub, Kim, Yumi, Li, Endan, Park, Seungjoon

“…Glutamate excitotoxicity is emerging as a contributor to degeneration of spinal cord motoneurons in amyotrophic lateral sclerosis (ALS). Recently, we have…”
Get full text

Ghrelin Protects Spinal Cord Motoneurons Against Chronic Glutamate Excitotoxicity by Inhibiting Microglial Activation by Lee, Sung-Youb, Kim, Yu-Mi, Li, Endan, Park, Seung-Joon

“…Glutamate excitotoxicity is emerging as a contributor to degeneration of spinal cord motoneurons in amyotrophic lateral sclerosis (ALS). Recently, we have…”
Get full text

A novel HDAC6 inhibitor, CKD-504, is effective in treating preclinical models of huntington's disease by Li, Endan, Choi, Jiwoo, Sim, Hye-Ri, Kim, Jiyeon, Jun, Jae Hyun, Kyung, Jangbeen, Ha, Nina, Kim, Semi, Ryu, Keun Ho, Chung, Seung Soo, Kim, Hyun Sook, Lee, Sungsu, Seol, Wongi, Song, Jihwan

“…Huntington's disease (HD) is a neurodegenerative disorder, of which pathogenesis is caused by a polyglutamine expansion in the amino-terminus of huntingtin…”
Get full text

Neural stem cells derived from the developing forebrain of YAC128 mice exhibit pathological features of Huntington’s disease by Li, Endan, Park, Hee Ra, Hong, Chang Pyo, Kim, Younghoon, Choi, Jiwoo, Lee, Suji, Park, Hyun Jung, Lee, Bomi, Kim, Tae Aug, Kim, Seong Jin, Kim, Hyun Sook, Song, Jihwan

“…Objectives Huntington's disease (HD) is a devastating neurodegenerative disease caused by polyglutamine (polyQ) expansion in the huntingtin (HTT) gene. Mutant…”
Get full text

Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidyl-3-kinase/Akt/glycogen synthase kinase-3beta pathways by Kim, Yumi, Lim, Eunjin, Lee, Sungyoub, Li, Endan, Park, Seungjoon

Get full text

Ghrelin has direct stimulatory effects in rat adult hippocampal progenitor cells. Ghrelin promotes proliferation and differentiation of rat adult hippocampal progenitor cells and regulates cell-cycle gene expression by Li, Endan, Chung, Hyunju, Lee, Sungyoub, Kim, Yumi, Lim, Eunjin, Park, Seungjoon

Get full text