Search Results - "Li, Dongtao Ni"
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Multistep Autoactivation of Asparaginyl Endopeptidase in Vitro and in Vivo
Published in The Journal of biological chemistry (03-10-2003)“…Mammalian asparaginyl endopeptidase (AEP) or legumain is a recently discovered lysosomal cysteine protease that specifically cleaves after asparagine residues…”
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Asparagine Endopeptidase Can Initiate the Removal of the MHC Class II Invariant Chain Chaperone
Published in Immunity (Cambridge, Mass.) (01-04-2003)“…The invariant chain (Ii) chaperone for MHC class II molecules is crucial for their effective function. Equally important is its removal. Cathepsins S or L are…”
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Novel cell-permeable acyloxymethylketone inhibitors of asparaginyl endopeptidase
Published in Biological chemistry (01-08-2003)“…Mammalian asparaginyl endopeptidase (AEP) or legumain is a recently identified lysosomal cysteine protease belonging to clan CD. To date it has been shown to…”
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Journal Article