Search Results - "Li, Di"
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Strategic Approaches to Optimizing Peptide ADME Properties
Published in The AAPS journal (01-01-2015)“…Development of peptide drugs is challenging but also quite rewarding. Five blockbuster peptide drugs are currently on the market, and six new peptides received…”
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Glycogen synthesis and beyond, a comprehensive review of GSK3 as a key regulator of metabolic pathways and a therapeutic target for treating metabolic diseases
Published in Medicinal research reviews (01-03-2022)“…Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved serine/threonine protein kinase first identified as an enzyme that regulates glycogen…”
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Assessing victim drug-drug interaction – Reaction phenotyping of CYP and non-CYP
Published in Drug metabolism and pharmacokinetics (01-04-2024)Get full text
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What is the role of CYP1A1 in drug metabolism?
Published in Drug metabolism and pharmacokinetics (01-04-2024)Get full text
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Reaction phenotyping to assess victim drug-drug interaction risks
Published in Expert opinion on drug discovery (02-11-2017)“…Reaction phenotyping provides critical information regarding the fraction metabolized (f ) of drug candidates. It has become increasingly important in drug…”
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From Criticism and Rejection to Sino-Western Communication: The Evolution of Zheng Guanying’s Understanding of the Spread of Christianity in China
Published in Religions (Basel, Switzerland ) (01-06-2024)“…Zheng Guanying paid close attention to the issue of the spread of Christianity in China since his youth. Over a period of more than three decades, he produced…”
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LPA kringle IV type 2 is associated with type 2 diabetes in a Chinese population with very high cardiovascular risk
Published in Journal of lipid research (01-05-2018)“…The connection between lipoprotein (a) [Lp(a)] levels and the risks of cardiovascular disease and diabetes remains poorly understood. Lp(a) is encoded by the…”
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Task Scheduling Based on a Hybrid Heuristic Algorithm for Smart Production Line with Fog Computing
Published in Sensors (Basel, Switzerland) (28-02-2019)“…Fog computing provides computation, storage and network services for smart manufacturing. However, in a smart factory, the task requests, terminal devices and…”
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ADAR1 Editing and its Role in Cancer
Published in Genes (25-12-2018)“…It is well established that somatic mutations and escape of immune disruption are two essential factors in cancer initiation and progression. With an…”
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Special Issue “Functional Biomolecule-Based Composites and Nanostructures: Current Developments and Applications—A Themed Issue in Honor of Prof. Dr. Itamar Willner”
Published in Chemistry an international journal (01-01-2024)“…This Special Issue of Chemistry is a themed issue of “Functional Biomolecule-Based Composites and Nanostructures: Current Developments and Applications” in…”
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The expanding role of prodrugs in contemporary drug design and development
Published in Nature reviews. Drug discovery (01-08-2018)“…Prodrug strategies can be used to overcome pharmacokinetic and pharmacodynamic issues in many therapeutic agents. Here, Rautio and colleagues discuss which…”
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The Design and Implementation of XiaoIce, an Empathetic Social Chatbot
Published in Computational linguistics - Association for Computational Linguistics (01-03-2020)“…This article describes the development of Microsoft , the most popular social chatbot in the world. XiaoIce is uniquely designed as an artifical intelligence…”
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A Blockchain-Based Solution for Enhancing Security and Privacy in Smart Factory
Published in IEEE transactions on industrial informatics (01-06-2019)“…Through the Industrial Internet of Things (IIoT), a smart factory has entered the booming period. However, as the number of nodes and network size become…”
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Controlling carbon self-doping site of g-C3N4 for highly enhanced visible-light-driven hydrogen evolution
Published in Applied catalysis. B, Environmental (05-10-2019)“…[Display omitted] By skillfully replacing one nitrogen among the triazine of g-C3N4 with carbon atom, the as-prepared CNU0.075 sample not only increases…”
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Recent Advances in Multiresponsive Flexible Sensors towards E‐skin: A Delicate Design for Versatile Sensing
Published in Small (Weinheim an der Bergstrasse, Germany) (01-02-2022)“…Multiresponsive flexile sensors with strain, temperature, humidity, and other sensing abilities serving as real electronic skin (e‐skin) have manifested great…”
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Implementing Smart Factory of Industrie 4.0: An Outlook
Published in International journal of distributed sensor networks (01-01-2016)“…With the application of Internet of Things and services to manufacturing, the fourth stage of industrialization, referred to as Industrie 4.0, is believed to…”
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Investigation on physical properties and modification mechanisms of diatomite/SBR modified asphalt
Published in PloS one (28-09-2023)“…In recent years, diatomite has been successfully adopted in asphalt modification to overcome the problems of polymer modified asphalt, because of the…”
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METTL3 Regulates Osteoblast Differentiation and Inflammatory Response via Smad Signaling and MAPK Signaling
Published in International journal of molecular sciences (27-12-2019)“…Osteoblasts are crucial bone-building cells that maintain bone homeostasis, whereas inflammatory stimuli can inhibit osteogenesis and activate inflammatory…”
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