Search Results - "Li, Chunrui"
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Co-seismic rupture of the 2021, M 7.4 Maduo earthquake (northern Tibet): Short-cutting of the Kunlun fault big bend
Published in Earth and planetary science letters (15-09-2022)Get full text
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Blocking TRPA1 and TNF-α Signal Improves Bortezomib-Induced Neuropathic Pain
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Bortezomib (BTZ) is largely used as a chemotherapeutic agent for the treatment of multiple myeloma. However, one of the significant limiting…”
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Viral infection/reactivation during long-term follow-up in multiple myeloma patients with anti-BCMA CAR therapy
Published in Blood cancer journal (New York) (18-10-2021)Get full text
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PPM1H is down-regulated by ATF6 and dephosphorylates p-RPS6KB1 to inhibit progression of hepatocellular carcinoma
Published in Molecular therapy. Nucleic acids (12-09-2023)“…We have shown previously that polymorphism of activating transcription factor 6 (ATF6) is associated with susceptibility to hepatocellular carcinoma (HCC)…”
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The exploration of B cell maturation antigen expression in plasma cell dyscrasias beyond multiple myeloma
Published in BMC cancer (07-02-2023)“…B cell maturation antigen (BCMA) targeted immunotherapies have demonstrated remarkable clinical efficacy in multiple myeloma (MM). Here, we evaluated the BCMA…”
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Postoperative analgesia using dezocine alleviates depressive symptoms after colorectal cancer surgery: A randomized, controlled, double-blind trial
Published in PloS one (26-05-2020)“…Postoperative depression is one of the most common mental disorders in patients undergoing cancer surgery and it often delays postoperative recovery. We…”
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Anti-BCMA CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma Patients With Extramedullary Disease: A Single Center Analysis of Two Clinical Trials
Published in Frontiers in immunology (29-10-2021)“…The prognosis of relapsed/refractory multiple myeloma (RRMM) patients with the extramedullary disease was significantly poor. Extramedullary multiple myeloma…”
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Anti-BCMA CAR-T cells for treatment of plasma cell dyscrasia: case report on POEMS syndrome and multiple myeloma
Published in Journal of hematology and oncology (22-10-2018)“…POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome still has no standard treatment. On the basis that both…”
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A novel two-step administration of XPO-1 inhibitor may enhance the effect of anti-BCMA CAR-T in relapsed/refractory extramedullary multiple myeloma
Published in Journal of translational medicine (15-11-2023)“…Abstract Background Extramedullary disease usually implies a dismal outcome in relapsed/refractory multiple myeloma patients, and requires novel treatment…”
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Efficacy of programmed cell death 1 inhibitor maintenance after chimeric antigen receptor T cells in patients with relapsed/refractory B-cell non-Hodgkin-lymphoma
Published in Cellular oncology (Dordrecht) (01-08-2024)“…Introduction Chimeric antigen receptor (CAR)-T cells obtained long-term durability in about 30% to 40% of relapsed/refractory (r/r) B-cell non-Hodgkin lymphoma…”
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Mutations in immunodeficiency-related genes may increase the risk of infection after CAR-T-cell therapy: a report of two cases
Published in BMC infectious diseases (22-02-2023)“…Chimeric antigen receptor T-cell therapy (CAR-T) has yielded unprecedented efficacy in B-cell malignancies. With the increasing use of CAR-T-cell therapy,…”
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Identification and Biochemical Properties of Two New Acetylcholinesterases in the Pond Wolf Spider (Pardosa pseudoannulata)
Published in PloS one (23-06-2016)“…Acetylcholinesterase (AChE), an important neurotransmitter hydrolase in both invertebrates and vertebrates, is targeted by organophosphorus and carbamate…”
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Oligosecretory Waldenström macroglobulinemia exhibits excellent treatment response and outcomes
Published in Haematologica (Roma) (01-02-2024)Get full text
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Effects of Lycium barbarum polysaccharides on the proliferation and differentiation of primary Sertoli cells in young rats
Published in Journal of Traditional Chinese Medical Sciences (01-01-2022)“…Objective: Sertoli cells (SCs) provide physical support and material supply for germ cells and participate in the formation of blood-testis barrier. The number…”
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Immunological alternation in COVID-19 patients with cancer and its implications on mortality
Published in Oncoimmunology (01-01-2021)“…Patients with malignancy were reportedly more susceptible and vulnerable to Coronavirus Disease 2019 (COVID-19), and witnessed a greater mortality risk in…”
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Risk factors for developing into critical COVID-19 patients in Wuhan, China: A multicenter, retrospective, cohort study
Published in EClinicalMedicine (01-08-2020)“…The ferocious global assault of COVID-19 continues. Critically ill patients witnessed significantly higher mortality than severe and moderate ones. Herein, we…”
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CD19/CD22 CAR-T-cell cocktail therapy following autologous transplantation is an optimizing strategy for treating relapsed/refractory central nervous system lymphoma
Published in Experimental hematology & oncology (13-10-2024)“…Relapsed/refractory (R/R) primary and secondary central nervous system lymphomas (PCNSL, SCNSL) are associated with short survival and represent an unmet need,…”
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A Model Perspective Explanation of the Long-Term Sustainability of a Fully Human BCMA-Targeting CAR (CT103A) T-Cell Immunotherapy
Published in Frontiers in pharmacology (02-02-2022)“…Different from canonical drugs, CAR T-cells are "living drugs", which derived from patient's own blood. Studies of the pharmacokinetics of CAR T-cells could…”
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A phase I study of anti‐BCMA CAR T cell therapy in relapsed/refractory multiple myeloma and plasma cell leukemia
Published in Clinical and translational medicine (01-03-2021)“…Background Relapsed/refractory (R/R) multiple myeloma (MM) patients and primary plasma cell leukemia (PCL) have an unfavorable prognosis and no effective…”
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