Search Results - "Li, Chu‐Xin"

Nanocatalyst‐Mediated Chemodynamic Tumor Therapy by Zhang, Lu, Li, Chu‐Xin, Wan, Shuang‐Shuang, Zhang, Xian‐Zheng

“…Traditional tumor treatments, including chemotherapy, radiotherapy, photodynamic therapy, and photothermal therapy, are developed and used to treat different…”
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Artificially Reprogrammed Macrophages as Tumor‐Tropic Immunosuppression‐Resistant Biologics to Realize Therapeutics Production and Immune Activation by Li, Chu‐Xin, Zhang, Yu, Dong, Xue, Zhang, Lu, Liu, Miao‐Deng, Li, Bin, Zhang, Ming‐Kang, Feng, Jun, Zhang, Xian‐Zheng

“…To engineer patient‐derived cells into therapy‐purposed biologics is a promising solution to realize personalized treatments. Without using gene‐editing…”
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Aggressive Man‐Made Red Blood Cells for Hypoxia‐Resistant Photodynamic Therapy by Liu, Wen‐Long, Liu, Tao, Zou, Mei‐Zhen, Yu, Wu‐Yang, Li, Chu‐Xin, He, Zu‐Yang, Zhang, Ming‐Kang, Liu, Miao‐Deng, Li, Zi‐Hao, Feng, Jun, Zhang, Xian‐Zheng

“…Extreme hypoxia of tumors represents the most notable barrier against the advance of tumor treatments. Inspired by the biological nature of red blood cells…”
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Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells by Liu, Wen-Long, Zou, Mei-Zhen, Liu, Tao, Zeng, Jin-Yue, Li, Xue, Yu, Wu-Yang, Li, Chu-Xin, Ye, Jing-Jie, Song, Wen, Feng, Jun, Zhang, Xian-Zheng

“…Most cancer vaccines are unsuccessful in eliciting clinically relevant effects. Without using exogenous antigens and adoptive cells, we show a concept of…”
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Optically-controlled bacterial metabolite for cancer therapy by Zheng, Di-Wei, Chen, Ying, Li, Zi-Hao, Xu, Lu, Li, Chu-Xin, Li, Bin, Fan, Jin-Xuan, Cheng, Si-Xue, Zhang, Xian-Zheng

“…Bacteria preferentially accumulating in tumor microenvironments can be utilized as natural vehicles for tumor targeting. However, neither current chemical nor…”
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Carbon-Dot-Decorated Carbon Nitride Nanoparticles for Enhanced Photodynamic Therapy against Hypoxic Tumor via Water Splitting by Zheng, Di-Wei, Li, Bin, Li, Chu-Xin, Fan, Jin-Xuan, Lei, Qi, Li, Cao, Xu, Zushun, Zhang, Xian-Zheng

“…Hypoxia, a typical feature of solid tumors, remarkably restricts the efficiency of photodynamic therapy (PDT). Here, a carbon nitride (C3N4)-based…”
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Engineered Bacterial Bioreactor for Tumor Therapy via Fenton‐Like Reaction with Localized H2O2 Generation by Fan, Jin‐Xuan, Peng, Meng‐Yun, Wang, He, Zheng, Hao‐Ran, Liu, Zong‐Lin, Li, Chu‐Xin, Wang, Xia‐Nan, Liu, Xin‐Hua, Cheng, Si‐Xue, Zhang, Xian‐Zheng

“…Synthetic biology based on bacteria has been displayed in antitumor therapy and shown good performance. In this study, an engineered bacterium Escherichia coli…”
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Expandable Immunotherapeutic Nanoplatforms Engineered from Cytomembranes of Hybrid Cells Derived from Cancer and Dendritic Cells by Liu, Wen‐Long, Zou, Mei‐Zhen, Liu, Tao, Zeng, Jin‐Yue, Li, Xue, Yu, Wu‐Yang, Li, Chu‐Xin, Ye, Jing‐Jie, Song, Wen, Feng, Jun, Zhang, Xian‐Zheng

“…Using the cytomembranes (FMs) of hybrid cells acquired from the fusion of cancer and dendritic cells (DCs), this study offers a biologically derived platform…”
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Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy by Zheng, Di-Wei, Lei, Qi, Zhu, Jing-Yi, Fan, Jin-Xuan, Li, Chu-Xin, Li, Cao, Xu, Zushun, Cheng, Si-Xue, Zhang, Xian-Zheng

“…Discovering advanced materials for regulating cell death is of great importance in the development of anticancer therapy. Herein, by harnessing the recently…”
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Nitric Oxide Release Device for Remote‐Controlled Cancer Therapy by Wireless Charging by Li, Bin, Ji, Ping, Peng, Si‐Yuan, Pan, Pei, Zheng, Di‐Wei, Li, Chu‐Xin, Sun, Yun‐Xia, Zhang, Xian‐Zheng

“…Traditional phototherapies face the issue that the insufficient penetration of light means it is difficult to reach deep lesions, which greatly reduces the…”
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Engineered Bacterial Bioreactor for Tumor Therapy via Fenton-Like Reaction with Localized H 2 O 2 Generation by Fan, Jin-Xuan, Peng, Meng-Yun, Wang, He, Zheng, Hao-Ran, Liu, Zong-Lin, Li, Chu-Xin, Wang, Xia-Nan, Liu, Xin-Hua, Cheng, Si-Xue, Zhang, Xian-Zheng

“…Synthetic biology based on bacteria has been displayed in antitumor therapy and shown good performance. In this study, an engineered bacterium Escherichia coli…”
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A Multifunctional Biomimetic Nanoplatform for Relieving Hypoxia to Enhance Chemotherapy and Inhibit the PD‐1/PD‐L1 Axis by Zou, Mei‐Zhen, Liu, Wen‐Long, Li, Chu‐Xin, Zheng, Di‐Wei, Zeng, Jin‐Yue, Gao, Fan, Ye, Jing‐Jie, Zhang, Xian‐Zheng

“…Hypoxia is reported to participate in tumor progression, promote drug resistance, and immune escape within tumor microenvironment, and thus impair therapeutic…”
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Interfering with Lactate‐Fueled Respiration for Enhanced Photodynamic Tumor Therapy by a Porphyrinic MOF Nanoplatform by Chen, Zhao‐Xia, Liu, Miao‐Deng, Zhang, Ming‐Kang, Wang, Shi‐Bo, Xu, Lu, Li, Chu‐Xin, Gao, Fan, Xie, Bo‐Ru, Zhong, Zhen‐Lin, Zhang, Xian‐Zheng

“…Lactate is a prominent energy substrate for oxidative tumor cells. Interfering with the lactate‐fueled respiration of oxidative tumor cells would be a…”
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Tumor Starvation Induced Spatiotemporal Control over Chemotherapy for Synergistic Therapy by Zhang, Ming‐Kang, Li, Chu‐Xin, Wang, Shi‐Bo, Liu, Tao, Song, Xian‐Lin, Yang, Xiao‐Quan, Feng, Jun, Zhang, Xian‐Zheng

“…By integrating the characteristics of each therapy modality and material chemistry, a multitherapy modality is put forward: tumor starvation triggered…”
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Photocatalyzing CO2 to CO for Enhanced Cancer Therapy by Zheng, Di‐Wei, Li, Bin, Li, Chu‐Xin, Xu, Lu, Fan, Jin‐Xuan, Lei, Qi, Zhang, Xian‐Zheng

“…Continuous exposure to carbon monoxide (CO) can sensitize cancer cells to chemotherapy while protect normal cells from apoptosis. The Janus face of CO thus…”
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Yolk‐Shell Structured Nanoflowers Induced Intracellular Oxidative/Thermal Stress Damage for Cancer Treatment by Liu, Miao‐Deng, Guo, Deng‐Ke, Zeng, Run‐Yao, Ye, Jing‐Jie, Wang, Shi‐Bo, Li, Chu‐Xin, Sun, Yun‐Xia, Cheng, Si‐Xue, Zhang, Xian‐Zheng

“…Cancer cells, with unique their metabolism, frequently exhibit a high level of redox homeostasis, which could be a feasible target for cancer treatment. Here,…”
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Bacteria‐Based Backpacks to Enhance Adoptive Macrophage Transfer against Solid Tumors by An, Jia‐Xin, Han, Zi‐Yi, Qin, You‐Teng, Li, Chu‐Xin, He, Jin‐Lian, Zhang, Xian‐Zheng

“…Adoptive cell therapy has emerged as a promising approach for cancer treatment. However, the transfer of macrophages exhibits limited efficacy against solid…”
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Hierarchical Micro‐/Nanostructures from Human Hair for Biomedical Applications by Zheng, Di‐Wei, Hong, Sheng, Xu, Lu, Li, Chu‐Xin, Li, Ke, Cheng, Si‐Xue, Zhang, Xian‐Zheng

“…With the prominent progress of biomedical engineering, materials with high biocompatibility and versatile functions are urgently needed. So far, hierarchical…”
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Platelet-Mimicking Biotaxis Targeting Vasculature-Disrupted Tumors for Cascade Amplification of Hypoxia-Sensitive Therapy by Zhang, Mingkang, Ye, Jing-Jie, Xia, Yu, Wang, Zi-Yang, Li, Chu-Xin, Wang, Xiao-Shuang, Yu, Wuyang, Song, Wen, Feng, Jun, Zhang, Xian-Zheng

“…Tumorous vasculature plays key roles in sustaining tumor growth. Vascular disruption is accompanied by internal coagulation along with platelet recruitment and…”
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Normalizing Tumor Microenvironment Based on Photosynthetic Abiotic/Biotic Nanoparticles by Zheng, Diwei, Li, Bin, Xu, Lu, Zhang, Qiu-Ling, Fan, Jin-Xuan, Li, Chu-Xin, Zhang, Xian-Zheng

“…Tumor hypoxia has attained the status of a core hallmark of cancer that globally affects the entire tumor phenotype. Reversing tumor hypoxia might offer…”
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