Search Results - "Li, Chenwen"

A Targeting Nanotherapy for Abdominal Aortic Aneurysms by Cheng, Juan, Zhang, Runjun, Li, Chenwen, Tao, Hui, Dou, Yin, Wang, Yuquan, Hu, Houyuan, Zhang, Jianxiang

“…Abdominal aortic aneurysm (AAA) is a leading cause of mortality and morbidity in the elderly. Currently, there remain no effective drugs that can prevent the…”
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Functionally integrating nanoparticles alleviate deep vein thrombosis in pregnancy and rescue intrauterine growth restriction by Cheng, Juan, Zhang, Siqi, Li, Chenwen, Li, Ke, Jia, Xiaoyan, Wei, Quanfang, Qi, Hongbo, Zhang, Jianxiang

“…There is still unmet demand for effective, safe, and patient-friendly anti-thrombotics to treat deep vein thrombosis (DVT) during pregnancy. Here we first…”
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A Proresolving Peptide Nanotherapy for Site‐Specific Treatment of Inflammatory Bowel Disease by Regulating Proinflammatory Microenvironment and Gut Microbiota by Li, Chenwen, Zhao, Yang, Cheng, Juan, Guo, Jiawei, Zhang, Qixiong, Zhang, Xiangjun, Ren, Jiong, Wang, Fengchao, Huang, Jun, Hu, Houyuan, Wang, Ruibing, Zhang, Jianxiang

“…The incidence and prevalence of inflammatory bowel disease (IBD) increases steadily worldwide. There is an urgent need for effective and safe IBD therapies…”
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Bioresponsive nanoplatforms for imaging and therapy of cardiovascular diseases by Li, Chenwen, Wu, Peng, Dou, Yin, Li, Qi, Zhang, Jianxiang

“…Cardiovascular diseases (CVDs) are still the first cause of death worldwide. Conventional small molecular diagnostic and therapeutic agents generally show…”
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Specific cancer stem cell-therapy by albumin nanoparticles functionalized with CD44-mediated targeting by Li, Yuanyuan, Shi, Sanjun, Ming, Yue, Wang, Linli, Li, Chenwen, Luo, Minghe, Li, Ziwei, Li, Bin, Chen, Jianhong

“…Cancer stem cells (CSCs) are highly proliferative and tumorigenic, which contributes to chemotherapy resistance and tumor occurrence. CSCs specific therapy may…”
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Early diagnosis of breast cancer lung metastasis by nanoprobe-based luminescence imaging of the pre-metastatic niche by Zheng, Hanwen, Yuan, Chunsen, Cai, Jiajun, Pu, Wendan, Wu, Peng, Li, Chenwen, Li, Gang, Zhang, Yang, Zhang, Jianxiang, Guo, Jiawei, Huang, Dingde

“…Early detection of breast cancer lung metastasis remains highly challenging, due to few metastatic cancer cells at an early stage. Herein we propose a new…”
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Intrinsically bioactive and biomimetic nanoparticle-derived therapies alleviate asthma by regulating multiple pathological cells by Cai, Jiajun, Tao, Hui, Liu, Huan, Hu, Yi, Han, Songling, Pu, Wendan, Li, Lanlan, Li, Gang, Li, Chenwen, Zhang, Jianxiang

“…Asthma is a serious global public health concern. Airway neutrophilic inflammation is closely related to severe asthma, for which effective and safe therapies…”
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Pathologically triggered in situ aggregation of nanoparticles for inflammation-targeting amplification and therapeutic potentiation by Nie, Qiang, Li, Chenwen, Wang, Yu, Hu, Yi, Pu, Wendan, Zhang, Qixiong, Cai, Jiajun, Lin, Yongyao, Li, Gang, Wang, Chenping, Li, Lanlan, Dou, Yin, Zhang, Jianxiang

“…Uncontrolled and persistent inflammation is closely related to numerous acute and chronic diseases. However, effective targeting delivery systems remain to be…”
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Bioresponsive drug delivery systems for the treatment of inflammatory diseases by Dou, Yin, Li, Chenwen, Li, Lanlan, Guo, Jiawei, Zhang, Jianxiang

“…Inflammation is intimately related to the pathogenesis of numerous acute and chronic diseases like cardiovascular disease, inflammatory bowel disease,…”
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Site‐Specific MicroRNA‐33 Antagonism by pH‐Responsive Nanotherapies for Treatment of Atherosclerosis via Regulating Cholesterol Efflux and Adaptive Immunity by Li, Chenwen, Dou, Yin, Chen, Yidan, Qi, Yuantong, Li, Lanlan, Han, Songling, Jin, Taotao, Guo, Jiawei, Chen, Jianhong, Zhang, Jianxiang

“…Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis…”
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Stem Cell‐Niche Engineering via Multifunctional Hydrogel Potentiates Stem Cell Therapies for Inflammatory Bone Loss by Li, Gang, Li, Zimeng, Li, Lanlan, Liu, Shan, Wu, Peng, Zhou, Min, Li, Chenwen, Li, Xiaodong, Luo, Gaoxing, Zhang, Jianxiang

“…Effective therapies capable of simultaneously inhibiting inflammation and promoting bone healing remain to be developed for inflammatory bone disease. Stem…”
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Hydrogel Transformed from Nanoparticles for Prevention of Tissue Injury and Treatment of Inflammatory Diseases by Li, Zimeng, Li, Gang, Xu, Jiajia, Li, Chenwen, Han, Songling, Zhang, Chunfan, Wu, Peng, Lin, Yongyao, Wang, Chenping, Zhang, Jianxiang, Li, Xiaodong

“…Functional hydrogels responsive to physiological and pathological signals have extensive biomedical applications owing to their multiple advanced attributes…”
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Reactive Oxygen Species-Responsive Transformable and Triple-Targeting Butylphthalide Nanotherapy for Precision Treatment of Ischemic Stroke by Normalizing the Pathological Microenvironment by Yang, Qinghua, Pu, Wendan, Hu, Kaiyao, Hu, Yi, Feng, Zhiqiang, Cai, Jiajun, Li, Chenwen, Li, Lanlan, Zhou, Zhenhua, Zhang, Jianxiang

“…High potency and safe therapies are still required for ischemic stroke, which is a leading cause of global death and disability. Herein, a reactive oxygen…”
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Reply: Doubts About the Targeting Nanotherapy for Abdominal Aortic Aneurysms by Cheng, Juan, Li, Chenwen, Zhang, Jianxiang

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Reply by Cheng, Juan, Li, Chenwen, Zhang, Jianxiang

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Zinc oxide/silver bimetallic nanoencapsulated in PVP/PCL nanofibres for improved antibacterial activity by Hu, Min, Li, Chenwen, Li, Xin, Zhou, Min, Sun, Jianbin, Sheng, Fangfang, Shi, Sanjun, Lu, Laichun

“…The anti-infection ability and skin regeneration are important aspects on the progress of wound healing, which needs an ideal wound dressing that not only…”
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Engineering of Biodegradable and Excretable Inflammation‐Resolving Materials by Wu, Peng, Gao, Mingjie, Zhang, Chunfan, Li, Chenwen, Li, Gang, Yan, Xinhao, Lai, Xiaodan, Zhang, Yang, Zhang, Jianxiang

“…Uncontrolled or chronic inflammation contributes to the pathogenesis of many acute/chronic diseases, such as acute organ injury, COVID‐19, and atherosclerosis…”
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A novel electrospun membrane based on moxifloxacin hydrochloride/poly(vinyl alcohol)/sodium alginate for antibacterial wound dressings in practical application by Fu, Ruoqiu, Li, Chenwen, Yu, Caiping, Xie, Hong, Shi, Sanjun, Li, Zhuoheng, Wang, Qing, Lu, Laichun

“…This study reports on the performance of sodium alginate (SA)/poly(vinyl alcohol) (PVA)/moxifloxacin hydrochloride (MH) nanofibrous membranes (NFM) capable of…”
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Bioinspired yeast microcapsules loaded with self-assembled nanotherapies for targeted treatment of cardiovascular disease by Zhang, Xiangjun, Xu, Xiaoqiu, Chen, Yidan, Dou, Yin, Zhou, Xing, Li, Lanlan, Li, Chenwen, An, Huijie, Tao, Hui, Hu, Houyuan, Li, Xiaohui, Zhang, Jianxiang

“…[Display omitted] We developed a biomimetic approach for targeted treatment of cardiovascular disease, which is mediated by a yeast-derived microcapsule (YC)…”
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A novel mitochondria‐targeting compound exerts therapeutic effects against melanoma by inducing mitochondria‐mediated apoptosis and autophagy in vitro and in vivo by Bai, Jun, Wang, Hailan, Li, Chenwen, Liu, Li, Wang, Jianv, Sun, Changzhen, Zhang, Qingbi

“…Melanoma is the most invasive skin cancer, with a high mortality rate. However, existing therapeutic drugs have side effects, low reactivity, and lead to drug…”
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