Search Results - "Li, Carrie J"

Dual inhibition of PI3K signaling and histone deacetylation halts proliferation and induces lethality in mantle cell lymphoma by Guo, Hui, Zeng, Dongfeng, Zhang, Hui, Bell, Taylor, Yao, Jun, Liu, Yang, Huang, Shengjian, Li, Carrie J., Lorence, Elizabeth, Zhou, Shouhao, Gong, Tiejun, Jiang, Changying, Ahmed, Makhdum, Yao, Yixin, Nomie, Krystle J., Zhang, Liang, Wang, Michael

“…The dysregulation of PI3K signaling has been implicated as an underlying mechanism associated with resistance to Bruton’s tyrosine kinase inhibition by…”
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Follicular helper T cells promote liver pathology in mice during Schistosoma japonicum infection by Chen, Xiaojun, Yang, Xiaowei, Li, Yong, Zhu, Jifeng, Zhou, Sha, Xu, Zhipeng, He, Lei, Xue, Xue, Zhang, Weiwei, Dong, Xiaoxiao, Wu, Henry, Li, Carrie J, Hsu, Hsiang-Ting, Kong, Wenjun, Liu, Feng, Tripathi, Prem B, Yu, Michelle S, Chang, Jason, Zhou, Liang, Su, Chuan

“…Following Schistosoma japonicum (S. japonicum) infection, granulomatous responses are induced by parasite eggs trapped in host organs, particular in the liver,…”
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Pleiotropic Action of Novel Bruton's Tyrosine Kinase Inhibitor BGB-3111 in Mantle Cell Lymphoma by Li, Carrie J, Jiang, Changying, Liu, Yang, Bell, Taylor, Ma, Wencai, Ye, Yin, Huang, Shengjian, Guo, Hui, Zhang, Hui, Wang, Lai, Wang, Jing, Nomie, Krystle, Zhang, Liang, Wang, Michael

“…Bruton's tyrosine kinase (BTK) is a key mediator of BCR-dependent cell growth signaling and a clinically effective therapeutic target in mantle cell lymphoma…”
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Structural optimization elaborates novel potent Akt inhibitors with promising anticancer activity by Liu, Yang, Yin, Yanzhen, Zhang, Zhen, Li, Carrie J., Zhang, Hui, Zhang, Daoguang, Jiang, Changying, Nomie, Krystle, Zhang, Liang, Wang, Michael L., Zhao, Guisen

“…Targeting of Akt has been validated as a well rationalized approach to cancer treatment, and represents a promising therapeutic strategy for aggressive…”
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Novel role of aquaporin‐4 in CD4+ CD25+ T regulatory cell development and severity of Parkinson’s disease by Chi, Ying, Fan, Yi, He, Lei, Liu, Wei, Wen, Xiaoyun, Zhou, Sha, Wang, Xuefeng, Zhang, Cui, Kong, Hui, Sonoda, Laura, Tripathi, Prem, Li, Carrie J., Yu, Michelle S., Su, Chuan, Hu, Gang

“…Summary Aquaporin‐4 (AQP4) is highly expressed in mammalian brains and is involved in the pathophysiology of cerebral disorders, including stroke, tumors,…”
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Metastatic ovarian papillary serous carcinoma to the breast: Diagnosis and pitfalls by Mhawech-Fauceglia, Paulette, Kay, Brian, Li, Carrie J, Lin, Yvonne G

“…Highlights ► The breast as a site of metastasis from primary ovarian carcinoma is uncommon. ► Distinguishing these metastases from primary breast tumors is…”
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Novel Bruton's Tyrosine Kinase Inhibitor Bgb-3111 Demonstrates Potent Activity in Mantle Cell Lymphoma by Li, Carrie J, Liu, Yang, Bell, Taylor, Wang, Jack, Guo, Hui, Ahmed, Makhdum, Zhang, Hui, Lam, Laura T, Nomie, Krystle, Wang, Lai, Zhang, Liang, Wang, Michael

“…Background: Aberrant B-cell receptor signaling is an important contributor to lymphomagenesis in mantle cell lymphoma (MCL). Bruton's Tyrosine Kinase (BTK), a…”
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Patient-Derived Xenograft Model in B-Cell Lymphoma: A Platform for a Personalized Clinical Trial by Bell, Taylor, Zhang, Hui, Ahmed, Makhdum, Guo, Hui, Li, Carrie J, Liu, Yang, Lam, Laura T, Chen, Zhihong, Wang, Jack, Zhang, Victoria, Nomie, Krystle, Zhang, Liang, Wang, Michael

“…Background: Imprecise correlation of treatment response in established cell line and cells obtained from patients (i.e., patient-primary) limits the…”
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Genetic and Molecular Characterization of Ibrutinib-Resistant Mantle Cell Lymphoma: Designing Innovative Therapeutic Strategies by Guo, Hui, Huang, Shengjian, Liu, Yang, Li, Carrie J, Wang, Jack, Zhang, Victoria, Ahmed, Makhdum, Lam, Laura T, Zhang, Hui, Nomie, Krystle, Zhang, Liang, Wang, Michael

“…Background Mantle cell lymphoma (MCL) is a B-cell malignancy with a broad spectrum of clinical, pathological, and biological features, and clinical evolution…”
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Targeting Oxphos Pathway Against Ibrutinib Resistance to Mantle Cell Lymphoma by Liu, Yang, Bell, Taylor, Zhang, Hui, Sun, Yuting, Li, Carrie J, Feng, Ningping, Huang, Shengjian, Guo, Hui, Wang, Jack, Ahmed, Makhdum, Zhang, Victoria, Lam, Laura T, Nomie, Krystle, Zhang, Liang, Di Francesco, Maria E, Marszalek, Joe, Wang, Michael

“…Background: Mantle cell lymphoma (MCL) is an aggressive B-cell malignancy that is initially responsive but ultimately relapses to frontline therapy. Ibrutinib,…”
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CUDC-907: An Oral HDAC/PI3K Dual Inhibitor with Strong Preclinical Efficacy in MCL Model by Boyle, Jordan N, Kim, Caroline R, Guo, Hui, Bell, Taylor, Huang, Shengjian, Li, Carrie J, Liu, Yang, Zhang, Hui, Wang, Jack, Zhang, Victoria, Ahmed, Makhdum, Lam, Laura T, Nomie, Krystle, Zhang, Liang, Zeng, Dongfeng, Wang, Michael

“…Introduction Mantle cell lymphoma (MCL) is an aggressive lymphoma with elevated B-cell receptor activity. Ibrutinib (IBN), a Bruton's tyrosine kinase (BTK)…”
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Pre-Clinical Evaluation of the PI3K-p110β/δ Inhibitor KA2237 in Mantle Cell Lymphoma by Huang, Shengjian, Nastoupil, Loretta J., Guo, Hui, Bell, Taylor, Ahmed, Makhdum, Li, Carrie J, Wang, Jack, Liu, Yang, Zhang, Victoria, Kim, Caroline R, Boyle, Jordan N, Lorence, Elizabeth A, Lam, Laura T, Chen, Zhihong, Zhang, Hui, Shuttleworth, Stephen Joseph, Nomie, Krystle, Wang, Michael, Zhang, Liang

“…Background: Mantle cell lymphoma (MCL) accounts for 6% of all non-Hodgkin lymphoma and is a therapeutic challenge. Phosphoinositide-3 kinase (PI3K) has been…”
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Follicular Helper T Cells Promote Liver Pathology in Mice during Schistosoma japonicum Infection: e1004097 by Chen, Xiaojun, Yang, Xiaowei, Li, Yong, Zhu, Jifeng, Zhou, Sha, Xu, Zhipeng, He, Lei, Xue, Xue, Zhang, Weiwei, Dong, Xiaoxiao, Wu, Henry, Li, Carrie J, Hsu, Hsiang-Ting, Kong, Wenjun, Liu, Feng, Tripathi, Prem B, Yu, Michelle S, Chang, Jason, Zhou, Liang, Su, Chuan

“…Following Schistosoma japonicum (S. japonicum) infection, granulomatous responses are induced by parasite eggs trapped in host organs, particular in the liver,…”
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Novel role of aquaporin-4 in CD4+ CD25+ T regulatory cell development and severity of Parkinson’s disease: AQP4 in Treg cell development and severity of PD by Chi, Ying, Fan, Yi, He, Lei, Liu, Wei, Wen, Xiaoyun, Zhou, Sha, Wang, Xuefeng, Zhang, Cui, Kong, Hui, Sonoda, Laura, Tripathi, Prem, Li, Carrie J., Yu, Michelle S., Su, Chuan, Hu, Gang

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