Search Results - "Li, Billy"
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RADAR: a rigorously annotated database of A-to-I RNA editing
Published in Nucleic acids research (01-01-2014)“…We present RADAR--a rigorously annotated database of A-to-I RNA editing (available at http://RNAedit.com). The identification of A-to-I RNA editing sites has…”
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Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing
Published in Science (American Association for the Advancement of Science) (29-05-2009)“…Adenosine-to-inosine (A-to-I) RNA editing leads to transcriptome diversity and is important for normal brain function. To date, only a handful of functional…”
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The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers
Published in Cancer cell (12-10-2015)“…Adenosine-to-inosine (A-to-I) RNA editing is a widespread post-transcriptional mechanism, but its genomic landscape and clinical relevance in cancer have not…”
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Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs
Published in Genome Biology (30-10-2017)“…One of the most prevalent forms of post-transcritpional RNA modification is the conversion of adenosine nucleosides to inosine (A-to-I), mediated by the ADAR…”
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Enhanced Specificity and Efficiency of the CRISPR/Cas9 System with Optimized sgRNA Parameters in Drosophila
Published in Cell reports (Cambridge) (06-11-2014)“…The CRISPR/Cas9 system has recently emerged as a powerful tool for functional genomic studies in Drosophila melanogaster. However, single-guide RNA (sgRNA)…”
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Multifaceted roles of RNA editing enzyme ADAR1 in innate immunity
Published in RNA (Cambridge) (01-05-2024)“…Innate immunity must be tightly regulated to enable sensitive pathogen detection while averting autoimmunity triggered by pathogen-like host molecules. A…”
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Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila
Published in Nature communications (27-03-2020)“…ADAR RNA editing enzymes are high-affinity dsRNA-binding proteins that deaminate adenosines to inosines in pre-mRNA hairpins and also exert editing-independent…”
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Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens
Published in Nature genetics (01-12-2018)“…Phagocytosis is required for a broad range of physiological functions, from pathogen defense to tissue homeostasis, but the mechanisms required for…”
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Identification of human RNA editing sites: A historical perspective
Published in Methods (San Diego, Calif.) (01-09-2016)“…•Historical review of methods to identify A-to-I RNA editing sites.•Our ability to identify editing sites is heavily dependent on the DNA sequencing…”
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Using Kinect for face recognition under varying poses, expressions, illumination and disguise
Published in 2013 IEEE Workshop on Applications of Computer Vision (WACV) (01-01-2013)“…We present an algorithm that uses a low resolution 3D sensor for robust face recognition under challenging conditions. A preprocessing algorithm is proposed…”
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Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis
Published in Nature communications (12-04-2021)“…Adenosine-to-inosine (A-to-I) RNA editing catalyzed by ADAR enzymes occurs in double-stranded RNAs. Despite a compelling need towards predictive understanding…”
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Robust RGB-D face recognition using Kinect sensor
Published in Neurocomputing (Amsterdam) (19-11-2016)“…In this paper we propose a robust face recognition algorithm for low resolution RGB-D Kinect data. Many techniques are proposed for image preprocessing due to…”
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Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs
Published in Nature methods (01-07-2018)“…Molecular tools that target RNA at specific sites allow recoding of RNA information and processing. SNAP-tagged deaminases guided by a chemically stabilized…”
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Deciphering the functions and regulation of brain-enriched A-to-I RNA editing
Published in Nature neuroscience (01-11-2013)“…Brain enriched RNA editing of Adenosine-to-Inosine (A-to-I) increases the amount of information encoded in the genome and diversifies the transcriptome. Here…”
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RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
Published in Science (American Association for the Advancement of Science) (04-09-2015)“…Adenosine-to-inosine (A-to-I) editing is a highly prevalent posttranscriptional modification of RNA, mediated by ADAR (adenosine deaminase acting on RNA)…”
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Accurate identification of human Alu and non-Alu RNA editing sites
Published in Nature methods (01-06-2012)“…A computational framework is reported for the accurate and sensitive identification of RNA editing sites from whole-genome DNA and RNA sequences from the same…”
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Assessing the Impact of Population Dynamics on Poverty Measures: A Decomposition Analysis
Published in Social indicators research (01-11-2017)“…Reducing income inequality is one of the seventeen Sustainable Development Goals recently announced by United Nations. A relative poverty concept adopted by…”
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Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses
Published in The Journal of biological chemistry (18-03-2016)“…Adenosine deaminases acting on double-stranded RNA (ADARs) catalyze the deamination of adenosine (A) to produce inosine (I) in double-stranded (ds) RNA…”
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Face recognition based on Kinect
Published in Pattern analysis and applications : PAA (01-11-2016)“…In this paper, we present a new algorithm that utilizes low-quality red, green, blue and depth (RGB-D) data from the Kinect sensor for face recognition under…”
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The evolution and adaptation of A-to-I RNA editing
Published in PLoS genetics (28-11-2017)“…Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification that affects the information encoded from DNA to RNA to protein…”
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