Search Results - "Li, Anzhong"
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Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus
Published in Nature communications (09-10-2019)“…N -methyladenosine (m A) is the most prevalent internal modification of mRNAs in most eukaryotes. Here we show that RNAs of human respiratory syncytial virus…”
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2
A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein
Published in Nature communications (03-08-2018)“…Current efforts to develop Zika virus (ZIKV) subunit vaccines have been focused on pre-membrane (prM) and envelope (E) proteins, but the role of NS1 in…”
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3
Efficient Production of Human Norovirus-Specific IgY in Egg Yolks by Vaccination of Hens with a Recombinant Vesicular Stomatitis Virus Expressing VP1 Protein
Published in Viruses (16-05-2019)“…Human norovirus (HuNoV) is responsible for more than 95% of outbreaks of acute nonbacterial gastroenteritis worldwide. Despite major efforts, there are no…”
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4
Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus
Published in Nature communications (09-10-2019)“…N 6 -methyladenosine (m 6 A) is the most prevalent internal modification of mRNAs in most eukaryotes. Here we show that RNAs of human respiratory syncytial…”
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Journal Article -
5
A Lactic Acid Bacteria (LAB)-Based Vaccine Candidate for Human Norovirus
Published in Viruses (02-03-2019)“…Human noroviruses (HuNoVs) are responsible for more than 95% of the non-bacterial acute gastroenteritis epidemics in the world. The CDC estimates that every…”
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Non-Segmented Negative-Sense RNA Viruses as Vectors for Developing Vaccine Candidates Against Zika Virus Infection
Published 01-01-2024“…Zika virus (ZIKV) is a member of the family Flaviviridae which includes many other important mosquito-borne viruses such as dengue virus (DENV), West Nile…”
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Dissertation -
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Porcine Epidemic Diarrhea Virus Deficient in RNA Cap Guanine-N-7 Methylation Is Attenuated and Induces Higher Type I and III Interferon Responses
Published in Journal of virology (30-07-2020)“…The 5' cap methylation of viral RNA plays important roles in RNA stability, efficient translation, and immune evasion. Thus, RNA cap methylation is an…”
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N 6 -methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I
Published in Nature microbiology (01-04-2020)“…Internal N -methyladenosine (m A) modification is one of the most common and abundant modifications of RNA. However, the biological roles of viral RNA m A…”
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Journal Article -
9
Internal N 6-methyladenosine modification controls the innate immune response to viral RNA
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Internal N6-methyladenosine (m6A) modification is one of the most prevalent and abundant modifications of RNA. The m6A methylation is catalyzed by…”
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10
A safe and highly efficacious measles virus-based vaccine expressing SARS-CoV-2 stabilized prefusion spike
Published in Proceedings of the National Academy of Sciences - PNAS (23-03-2021)“…The current pandemic of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights an urgent need to develop a safe,…”
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A Methyltransferase-Defective Vesicular Stomatitis Virus-Based SARS-CoV-2 Vaccine Candidate Provides Complete Protection against SARS-CoV-2 Infection in Hamsters
Published in Journal of virology (27-09-2021)“…The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to dramatic economic…”
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12
Stable Attenuation of Human Respiratory Syncytial Virus for Live Vaccines by Deletion and Insertion of Amino Acids in the Hinge Region between the mRNA Capping and Methyltransferase Domains of the Large Polymerase Protein
Published in Journal of virology (23-11-2020)“…Human respiratory syncytial virus (RSV) is the leading viral cause of lower respiratory tract disease in infants and children worldwide. Currently, there are…”
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13
Vesicular Stomatitis Virus and DNA Vaccines Expressing Zika Virus Nonstructural Protein 1 Induce Substantial but Not Sterilizing Protection against Zika Virus Infection
Published in Journal of virology (17-08-2020)“…The nonstructural protein 1 (NS1) of several flaviviruses, including West Nile, dengue, and yellow fever viruses, is capable of inducing variable degrees of…”
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14
N 6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Internal N6-methyladenosine (m6A) modification of RNA is one of the most abundant modifications in eukaryotic cells as well as in viruses. However,…”
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Journal Article -
15
Novel non-segmented negative-sense RNA virus-based vaccine platforms for Zika virus
Published in The Journal of immunology (1950) (01-05-2020)“…Abstract Zika virus (ZIKV) is a mosquito-borne flavivirus that can cause Congenital Zika Syndrome (including microcephaly), Guillain-Barré syndrome, and other…”
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EEFA: Energy Efficiency Frame Aggregation Scheduling Algorithm for IEEE 802.11n Wireless Network
Published in 中国通信 (01-03-2014)“…Packet size is restricted due to the error-prone wireless channel which drops the network energy utilization. Furthermore, the frequent packet retransmissions…”
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Journal Article -
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N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I
Published in Nature microbiology (01-04-2020)“…Internal N 6 -methyladenosine (m 6 A) modification is one of the most common and abundant modifications of RNA. However, the biological roles of viral RNA m 6…”
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Journal Article