Search Results - "Li, Albert Mao"
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β-Cell Succinate Dehydrogenase Deficiency Triggers Metabolic Dysfunction and Insulinopenic Diabetes
Published in Diabetes (New York, N.Y.) (01-07-2022)“…Mitochondrial dysfunction plays a central role in type 2 diabetes (T2D); however, the pathogenic mechanisms in pancreatic β-cells are incompletely elucidated…”
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p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen
Published in The Journal of cell biology (02-11-2020)“…The mechanisms by which TP53, the most frequently mutated gene in human cancer, suppresses tumorigenesis remain unclear. p53 modulates various cellular…”
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Abstract 5713: Reprogramming of serine metabolism during breast cancer progression
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…The causes and consequences of metabolic reprogramming during human breast cancer metastasis remain largely unknown. We performed metabolomics in the human…”
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Abstract 3905: Epigenetic primming reveals the central role of epigenetic state in the anti-tumor activity of vitamin D in pancreatic ductal adenocarcinoma
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, which is largely due to the intrinsic resistance to a broad spectrum of therapies. Vitamin D…”
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