Search Results - "Lezoualc'h, F"

Identification of Prominin‐2 as a new player of cardiomyocyte senescence in the aging heart by Maggiorani, D., Santin, Y., Formoso, K., Drapé, E., Martini, H., Brun, S., Cousin, G., Lairez, O., Lezoualc'h, F., Parini, A., Douin‐Echinard, V., Mialet‐Perez, J.

“…The aging heart is characterized by a number of structural changes leading to ventricular stiffness, impaired resistance to stress and increased risk of…”
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Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B by Muñoz-Llancao, Pablo, Henríquez, Daniel R, Wilson, Carlos, Bodaleo, Felipe, Boddeke, Erik W, Lezoualc'h, Frank, Schmidt, Martina, González-Billault, Christian

“…Acquisition of neuronal polarity is a complex process involving cellular and molecular events. The second messenger cAMP is involved in axonal specification…”
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Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice by Cachard-Chastel, M., Devers, S., Sicsic, S., Langlois, M., Lezoualc’h, F., Gardier, A.M., Belzung, C.

“…It is known that 5-HT 4 receptor agonists increase sAPPα levels in the cortex and hippocampus of mice as well as in a model of Alzheimer's disease (AD). As…”
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A Versatile Vector for Gene and Oligonucleotide Transfer into Cells in Culture and in vivo: Polyethylenimine by Boussif, Otmane, Frank Lezoualc'h, Zanta, Maria Antonietta, Mergny, Mojgan Djavaheri, Scherman, Daniel, Demeneix, Barbara, Behr, Jean-Paul

“…Several polycations possessing substantial buffering capacity below physiological pH, such as lipopolyamines and polyamidoamine polymers, are efficient…”
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5‐HT 4 receptor agonists increase sAPPα levels in the cortex and hippocampus of male C57BL/6j mice by Cachard‐Chastel, M, Lezoualc'h, F, Dewachter, I, Deloménie, C, Croes, S, Devijver, H, Langlois, M, Van Leuven, F, Sicsic, S, Gardier, A M

“…Background and purpose: A strategy to treat Alzheimer's disease (AD) is to increase the soluble form of amyloid precursor protein (sAPPα), a promnesic protein,…”
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Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57B1/6j mice by CACHARD-CHASTEL, M, DEVERS, S, SICSIC, S, LANGLOIS, M, LEZOUALC'H, F, GARDIER, A. M, BELZUNG, C

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5‐HT4 receptor agonists increase sAPPα levels in the cortex and hippocampus of male C57BL/6j mice by Cachard‐Chastel, M, Lezoualc'h, F, Dewachter, I, Deloménie, C, Croes, S, Devijver, H, Langlois, M, Leuven, F, Sicsic, S, Gardier, A M

“…Background and purpose: A strategy to treat Alzheimer's disease (AD) is to increase the soluble form of amyloid precursor protein (sAPPα), a promnesic protein,…”
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Transcription factor NF-κB: friend or foe of neurons? by LEZOUALC'H, F, BEHL, C

“…It is now well established that a number of neurological disorders such as Parkinson's disease and Alzheimer's disease are characterized by the formation of…”
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Melatonin prevents oxidative stress-induced cell death in hippocampal cells by Lezoualc'h, F, Skutella, T, Widmann, M, Behl, C

“…The pineal hormone melatonin has been suggested to be a very effective antioxidant in the brain. Oxidative stress may play a role in certain neuropathological…”
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The serotonin 5-HT 4 receptor and the amyloid precursor protein processing by Lezoualc'h, Frank, Robert, Sylvain J

“…A large body of evidence supports a major role for the serotonin 5-HT 4 receptor in learning and memory and it is suggested that 5-HT 4 agonists may be…”
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Oxidative stress-resistant cells are protected against haloperidol toxicity by Behl, C., Lezoualc'h, F., Widmann, M., Rupprecht, R., Holsboer, F.

“…The neuroleptic drug haloperidol is cytotoxic to cells of different origin in high doses. The mechanism of haloperidol toxicity may involve oxidative stress…”
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Bcl-2 prevents hippocampal cell death induced by the neuroleptic drug haloperidol by Lezoualc'h, F, Rupprecht, R, Holsboer, F, Behl, C

“…The proto-oncogene bcl-2 can rescue cells from apoptosis and necrosis and its mechanism of action may involve antioxidant activity. The possible involvement of…”
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Assignment of the beta-thyroid hormone receptor to 3,5,3'-triiodothyronine-dependent inhibition of transcription from the thyrotropin-releasing hormone promoter in chick hypothalamic neurons by Lezoualc'h, F, Hassan, A H, Giraud, P, Loeffler, J P, Lee, S L, Demeneix, B A

“…Thyroid hormone, T3, is essential to the normal development and metabolism of vertebrates. Fine tuning of circulating levels of T3 is critical and involves…”
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Neuroprotection against oxidative stress by estrogens: structure-activity relationship by Behl, C, Skutella, T, Lezoualc'h, F, Post, A, Widmann, M, Newton, C J, Holsboer, F

“…Oxidative stress-induced neuronal cell death has been implicated in different neurological disorders and neurodegenerative diseases; one such ailment is…”
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Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro by BEHL, C, LEZOUALC'H, F, TRAPP, T, WIDMANN, M, SKUTELLA, T, HOLSBOER, F

“…In patients with Alzheimer's disease, hippocampal cells are among the first neuronal cells of the brain to degenerate. Both rat primary hippocampal neurons and…”
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P3116New role of EPAC1 in Anthracycline-induced cardiotoxicity and anticancer therapy by Belhadef, A, Ribeiro, M, Mazevet, M, Laudette, M, Crozatier, B, Lezoualc'h, F, Benitah, J.-P, Gomez, A.-M, Lemaire, C, Morel, E

“…Abstract Introduction Doxorubicin (Dox) is an anthracycline commonly used to treat many types of cancer; unfortunately this chemotherapeutic agent induces many…”
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Towards a Large-Scale Assessment of the Relationship between Biological and Chronological Aging: The INSPIRE Mouse Cohort by Santin, Y, Lopez, S, Ader, I, Andrieu, S, Blanchard, N, Carrière, A, Casteilla, L, Cousin, B, Davezac, N, De Souto Barreto, P, Dray, C, Fazilleau, N, Gonzalez-Dunia, D, Gourdy, P, Guyonnet, S, Jabrane-Ferrat, N, Kunduzova, O, Lezoualc'h, F, Liblau, R, Martinez, L O, Moro, C, Payoux, P, Pénicaud, L, Planat-Bénard, V, Rampon, C, Rolland, Y, Schanstra, J-P, Sierra, F, Valet, P, Varin, A, Vergnolle, N, Vellas, B, Viña, J, Guiard, B P, Parini, A

“…Aging is the major risk factor for the development of chronic diseases. After decades of research focused on extending lifespan, current efforts seek primarily…”
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New Arylpiperazine Derivatives as Antagonists of the Human Cloned 5-HT4 Receptor Isoforms by Curtet, Sophie, Soulier, Jean-Louis, Zahradnik, Ivan, Giner, Mireille, Berque-Bestel, Isabelle, Mialet, Jeanne, Lezoualc'h, Frank, Donzeau-Gouge, Patrick, Sicsic, Sames, Fischmeister, Rodolphe, Langlois, Michel

“…New derivatives of arylpiperazine 9 were designed from ML 10302, a potent 5-HT4 receptor agonist in the gastrointestinal system. Compounds were synthesized by…”
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Inhibition of mitochondrial MAO-A/4-HNE pathway mitigates post-Myocardial Infarction remodeling by Santin, Y., Fazal, L., Sainte-Marie, Y., Tortosa, F., Teyssedre, L., Rouquette, J., Lezoualc'h, F., Mialet-Perez, J.

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Acute heart failure: mechanisms and pre-clinical models—a Scientific Statement of the ESC Working Group on Myocardial Function by Ciccarelli, Michele, Pires, Inês Falcão, Bauersachs, Johann, Bertrand, Luc, Beauloye, Christophe, Dawson, Dana, Hamdani, Nazha, Hilfiker-Kleiner, Denise, van Laake, Linda W, Lezoualc’h, Frank, Linke, Wolfgang A, Lunde, Ida G, Rainer, Peter P, Rispoli, Antonella, Visco, Valeria, Carrizzo, Albino, Ferro, Matteo Dal, Stolfo, Davide, van der Velden, Jolanda, Zacchigna, Serena, Heymans, Stephane, Thum, Thomas, Tocchetti, Carlo Gabriele

“…Abstract While chronic heart failure (CHF) treatment has considerably improved patient prognosis and survival, the therapeutic management of acute heart…”
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