Search Results - "Lezheiko, T. V."

Assessing the impact of the de novo SLC6A1 mutation in schizophrenia through a comprehensive case study by Kondratyev, NV, Alfimova, MV, Kaleda, VG, Lezheiko, TV, Mikhailova, VA, Karpov, DS, Ublinsky, MV, Ushakov, VL, Lebedeva, IS, Golimbet, VE

“…•The patient with an SLC6A1 mutation, typically linked to disorders like epilepsy and autism, exhibited symptoms consistent with schizophrenia and bipolar…”
Get full text

Studies of the Association between the Kynurenine-3-Monooxygenase Gene and Depression by Lezheiko, T. V., Golimbet, V. E., Andryushchenko, A. V., Melik-Pashayan, A. E., Mironova, E. V.

“…Objective. To study the association between the kynurenine-3-monooxygenase (KMO) gene and depression. Materials and methods . Polymorphic loci rs2275163 (C/T)…”
Get full text

Season of birth/C-reactive protein gene interaction differentially affects negative symptoms domains in patients with schizophrenia by Lezheiko, T. V., Mikhailova, V. A., Gabaeva, M. V., Kolesina, N. Y., Golimbet, V. E.

“…Background Schizophrenia is a severe psychiatric disease caused by genetic and environmental factors or their interactions that can contribute across multiple…”
Get full text

Abundance of ribosomal RNA gene copies in the genomes of schizophrenia patients by Chestkov, I.V., Jestkova, E.M., Ershova, E.S., Golimbet, V.E., Lezheiko, T.V., Kolesina, N.Y., Porokhovnik, L.N., Lyapunova, N.A., Izhevskaya, V.L., Kutsev, S.I., Veiko, N.N., Kostyuk, S.V.

“…The ribosome is a critical component of the translation machinery. The key component of ribosomes is ribosomal RNA (rRNA). Dysregulation of rRNA biogenesis has…”
Get full text

Effects of Oxytocin Pathway Gene Polymorphisms and Adverse Childhood Experiences on the Recognition of Emotion in Schizophrenia Spectrum Disorders by Alfimova, M. V., Mikhailova, V. A., Gabaeva, M. V., Plakunova, V. V., Lezheiko, T. V., Golimbet, V. E.

“…Objectives. To assess the role of interactions between oxytocin pathway gene polymorphisms and adverse childhood experiences (ACE) in deficits of the…”
Get full text

Studies of the Relationship between Oxytocinergic System Genes, Perinatal Complications, and the Formation of Interpersonal Relationships in Schizophrenia Patients by Mikhailova, V. A., Lezheiko, T. V., Kolesina, N. Yu, Golimbet, V. E.

“…Objectives. To identify any relationship between the genes of the oxytocinergic pathway and psychosocial functioning in schizophrenia, i.e., the ability of…”
Get full text

Supportive evidence for the association between the T102C 5-HTR2A gene polymorphism and schizophrenia: A large-scale case–control and family-based study by Golimbet, V.E, Lavrushina, O.M, Kaleda, V.G, Abramova, L.I, Lezheiko, T.V

“…Abstract Serotonin type 2A receptors (5-HTR2A) have long been implicated in schizophrenia pathology. A decreased number of these receptors were found in…”
Get full text

Genetic Polymorphism of Cytokines IL-1β, IL-4, and TNF-α as a Factor Modifying the Influence of Adverse Childhood Experiences on the Symptoms of Schizophrenia by Alfimova, M. V., Korovaitseva, G. I., Gabaeva, M. V., Plakunova, V. V., Lezheiko, T. V., Golimbet, V. E.

“…Objectives . Working from the hypothesis that activation of the immune system is one of the mechanisms whereby early environmental factors influence the onset…”
Get full text

Copy number variations of satellite III (1q12) and ribosomal repeats in health and schizophrenia by Ershova, E.S., Malinovskaya, E.M., Golimbet, V.E., Lezheiko, T.V., Zakharova, N.V., Shmarina, G.V., Veiko, R.V., Umriukhin, P.E., Kostyuk, G.P., Kutsev, S.I., Izhevskaya, V.L., Veiko, N.N., Kostyuk, S.V.

“…Earlier we studied the copy number variations (CNVs) of ribosomal repeat (rDNA) and the satellite III fragment (1q12) (f-SatIII) in the cells of schizophrenia…”
Get full text

Prognostication of Functional Outcomes of Schizophrenia Using a Multigene Panel by Golubev, S. A., Lezheiko, T. V., Korovaitseva, G. I., Gabaeva, M. V., Kolesina, N. Yu, Kaleda, V. G., Golimbet, V. E.

“…Objectives. To compare groups of schizophrenia patients with different levels of functional outcomes and different frequencies of risk variants at polymorphic…”
Get full text

Association of the rs1344706 Polymorphism of the ZNF804A Gene with Induced EEG Rhythm Changes during Visual Perception of Verbal Stimuli in Healthy and Schizophrenic Subjects by Garakh, Zh. V., Golimbet, V. E., Larionova, E. V., Lezheiko, T. V., Strelets, V. B., Zaytseva, Yu. S.

“…The association of the rs1344706 polymorphism of the ZNF804A gene with EEG rhythm synchronization/ desynchronization parameters during the visual perception of…”
Get full text

Dataset on negative symptoms factors in patients with schizophrenia by Lezheiko, T.V., Kolesina, N.Yu, Golimbet, V.E.

“…Schizophrenia is a severe mental disorder characterized by positive and negative symptoms. The negative symptoms are highly relevant to the disease course and…”
Get full text

The association study of interleukin-1beta and interleukin-1 receptor antagonist and clinical symptoms of schizophrenia by Golimbet, V E, Korovaĭtseva, G I, Lezheĭko, T V, Abramova, L I, Kaleda, V G, Kolesina, N Iu, Kasparov, S V, Savel'eva, T M

“…Growing evidence suggest that interleukin-1beta (IL-1B) and interleukin-1 receptor antagonist (IL-1RN) are involved in the pathogenesis of schizophrenia. The…”
Get more information

ROS-Induced DNA Damage Associates with Abundance of Mitochondrial DNA in White Blood Cells of the Untreated Schizophrenic Patients by Kutsev, S. I., Veiko, Natalia, Kostyuk, Svetlana, Izevskaya, Vera L., Dolgikh, Olga A., Kolesina, N. Yu, Lezheiko, Tatyana V., Golimbet, Vera E., Ershova, Elizaveta, Jestkova, E. M., Chestkov, I. V., Kostyuk, G. P.

“…Objective. The aim of this study was (1) to examine the leukocyte mtDNA copy number (CN) in unmedicated (SZ (m−)) and medicated (SZ (m+)) male patients with…”
Get full text

Association of 5-HTTLPR Serotonin Transporter Gene Polymorphism and Val66Met Brain-Derived Neurotrophic Factor Gene Polymorphism with Auditory N100 Evoked Potential Amplitude in Patients with Endogenous Psychoses by Golimbet, V. E, Lebedeva, I. S, Korovaitseva, G. I, Lezheiko, T. V, Yumatova, P. E

“…We studied the relationship between genes of serotonin transporter and brain-derived neurotrophic factor and parameters of AEP N100 wave to a non-significant…”
Get full text

Epigenetic research of cognitive deficit in schizophrenia: some methodological considerations by Lezheiko, T V, Alfimova, M V

“…To highlights the problems of assessing cognitive deficits in schizophrenia, relevant to the epigenetic, as well as a wide range of other approaches to the…”
Get more information

Effects of the Interaction of the ANKK1/DRD2 TaqIA and HTR2C Cys23Ser Polymorphisms on Approach Motivation in Schizophrenia Patients and Healthy People by Alfimova, M. V., Korovaitseva, G. I., Lezheiko, T. V., Golubev, S. A., Snegireva, A. A., Sakharova, E. A., Golimbet, V. E.

“…Objective. To assess the association of the DRD2 gene and its interaction with the HTR2C gene with the characteristics of the hedonistic and activatory aspects…”
Get full text

Association of Genes for Proinflammatory Cytokines and Depression by Lezheiko, T. V., Andryushchenko, A. V., Korovaitseva, G. I., Kondratiev, N. V., Gabaeva, M. V., Krikova, E. V., Golimbet, V. E.

“…Objectives. To study the association between proinflammatory cytokines and depression. Materials and methods. The: IL-1β C-511T and TNF-α G-308A gene…”
Get full text

Data on association of the variation (rs1344706) in the ZNF804A gene with schizophrenia and its symptoms in the Russian population by Lezheiko, T.V., Romanov, D.V., Kolesina, N.Yu, Golimbet, V.E.

“…The polymorphism rs1344706 in the ZNF804A gene is one of the best-supported risk variants for schizophrenia. The association between ZNF804A rs1344706 and the…”
Get full text

Interaction effect of serotonin transporter gene and brain-derived neurotrophic factor on the platelet serotonin content in stroke patients by Golimbet, V E, Brusov, O S, Factor, M I, Zlobina, G P, Lezheĭko, T V, Lavrushina, O M, Petrova, E A, Savina, M A, Skvortsova, V I

“…Platelet serotonin content in patients in the acute period of stroke is an important index of clinical changes during the post stroke period as well as a…”
Get more information