Search Results - "Lezhava, Teimuraz"
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Epigenetic Variability of Ribosomal Cistrons of Acrocentric Chromatids of Chromosomes 14 in Fetuses and Newborns with Down Syndrome
Published in Cytology and genetics (01-10-2024)“…Following the completion of the Human Genome Project, the strategic focus of modern genetics shifted towards functional genomics, encompassing non-coding…”
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Peptide Epitalon activates chromatin at the old age
Published in Neuro-endocrinology letters (01-10-2003)“…OBJECTIVES and design. We have studied the effect of synthetic peptide Epitalon on the activity of ribosomal genes, denaturation parameters of total…”
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Epigenetic Activation of Ribosomal Cystrons in Chromatids of Acrocentric Chromosome 15th in Ductal Breast Cancer
Published in International journal of peptide research and therapeutics (09-02-2023)“…After the completion of the Human Genome Project, the strategic direction of modern genetics shifted towards functional genomics, which also includes…”
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Epigenetic Variations in Chromatin Caused by the Combination of Bioregulators with Heavy Metals During Aging
Published in International journal of peptide research and therapeutics (01-07-2022)“…The aim of this study was to determine the level of chromatin condensation, the frequency of chromosomal aberrations and sister chromatid exchanges, based on…”
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Normalization of Epigenetic Change in the Genome by Peptide Bioregulator (Ala–Glu–Asp–Gly) in Pulmonary Tuberculosis
Published in International journal of peptide research and therapeutics (01-06-2019)“…The aim of this study was to evaluate genetic and epigenetic variation of the genome in patients with sensitive pulmonary tuberculosis (PT) before and after…”
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Activation of Pericentromeric and Telomeric Heterochromatin in Cultured Lymphocytes from Old Individuals
Published in Annals of the New York Academy of Sciences (01-04-2007)“…: The functional characteristics of chromosomes (level of total heterochromatin, chromosome instability, and sister chromatid exchanges [SCEs]) were studied…”
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Epigenetic Regulation of “Aged” Heterochromatin by Peptide Bioregulator Cortagen
Published in International journal of peptide research and therapeutics (01-03-2015)“…Peptide bioregulator Cortagen (Ala-Glu-Asp-Pro) in humans demonstrated a pronounced therapeutic effect up on the structural and functional recovery of the…”
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Feature series: Bioscience around the globe: in focus: Georgia
Published in Cell cycle (Georgetown, Tex.) (01-10-2010)Get full text
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Chromosome and aging: genetic conception of aging
Published in Biogerontology (Dordrecht) (01-01-2001)“…The mutation level (chromosome aberrations covering telomere regions), modifications of chromosome structure (level of condensed chromatin identified by the…”
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Remodeling of heterochromatin induced by heavy metals in extreme old age
Published in AGE (01-09-2011)“…The levels of chromosome instability and heat absorption of chromatin have been studied in cultured lymphocytes derived from blood of 80–93- and 18–30-year-old…”
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A New Genetic Conception of Aging and the Possible Mechanisms of Aging Pathologies
Published in Annals of the New York Academy of Sciences (01-11-1998)Get full text
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Sister Chromatid Exchange in Human Lymphocytes in Extreme Age
Published in Proceedings of the Japan Academy, Series B (1987)Get full text
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Gerontology research in Georgia
Published in Biogerontology (Dordrecht) (01-04-2011)“…Gerontology research carried out in different scientific centers of Georgia follows the basic directions of most work in this field: epidemiology,…”
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Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people
Published in Biogerontology (Dordrecht) (01-01-2004)“…The effect of the synthetic peptide bioregulator Vilon on structural and facultative heterochromatin of cultured lymphocytes from old people has been studied…”
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Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people
Published in Biogerontology (Dordrecht) (2004)Get full text
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Cytogenetic and biochemical studies on the nucleolus organizing regions of chromosomes in in vivo and in vitro aging
Published in AGE (01-04-1992)Get full text
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