Search Results - "Lezana, José Luis"

Next-generation sequencing for identifying a novel/de novo pathogenic variant in a Mexican patient with cystic fibrosis: a case report by Martínez-Hernández, Angélica, Larrosa, Julieta, Barajas-Olmos, Francisco, García-Ortíz, Humberto, Mendoza-Caamal, Elvia C, Contreras-Cubas, Cecilia, Mirzaeicheshmeh, Elaheh, Lezana, José Luis, Orozco, Lorena

“…Mexico is among the countries showing the highest heterogeneity of CFTR variants. However, no de novo variants have previously been reported in Mexican…”
Get full text

Effect of oral glycine on the clinical, spirometric and inflammatory status in subjects with cystic fibrosis: a pilot randomized trial by Vargas, Mario H, Del-Razo-Rodríguez, Rosangela, López-García, Amando, Lezana-Fernández, José Luis, Chávez, Jaime, Furuya, María E Y, Marín-Santana, Juan Carlos

“…Patients with cystic fibrosis (CF) have airway inflammation that contributes to symptoms and to pulmonary function derangement. Current drugs used to diminish…”
Get full text

CFTR pathogenic variants spectrum in a cohort of Mexican patients with cystic fibrosis by Martínez-Hernández, Angélica, Mendoza-Caamal, Elvia C., Mendiola-Vidal, Namibia G., Barajas-Olmos, Francisco, Villafan-Bernal, José Rafael, Jiménez-Ruiz, Juan Luis, Monge-Cazares, Tulia, García-Ortiz, Humberto, Cubas, Cecilia Contreras, Centeno-Cruz, Federico, Alaez-Verson, Carmen, Ortega-Torres, Soraya, Luna-Castañeda, Adriana del C., Baca, Vicente, Lezana, José Luis, Orozco, Lorena

“…Molecular diagnosis of cystic fibrosis (CF) is challenging in Mexico due to the population's high genetic heterogeneity. To date, 46 pathogenic variants (PVs)…”
Get full text

Bacterial Subversion of Autophagy in Cystic Fibrosis by Flores-Vega, Verónica Roxana, Vargas-Roldán, Silvia Yalid, Lezana-Fernández, José Luis, Lascurain, Ricardo, Santos-Preciado, José Ignacio, Rosales-Reyes, Roberto

“…Cystic fibrosis (CF) is a genetic disease affecting more than 70,000 people worldwide. It is caused by a mutation in the cftr gene, a chloride ion transporter…”
Get full text

Oral Administration of Human Polyvalent IgG by Mouthwash as an Adjunctive Treatment of Chronic Oral Candidiasis by Pedraza-Sánchez, Sigifredo, Méndez-León, Julia I, Gonzalez, Yolanda, Ventura-Ayala, María Laura, Herrera, María Teresa, Lezana-Fernández, Jose Luis, Bellanti, Joseph A, Torres, Martha

“…is a commensal fungus that can cause disease ranging in severity from moderate to severe mucosal infections to more serious life-threating disseminated…”
Get full text

Disseminated Tuberculosis and Chronic Mucocutaneous Candidiasis in a Patient with a Gain-of-Function Mutation in Signal Transduction and Activator of Transcription 1 by Pedraza-Sánchez, Sigifredo, Lezana-Fernández, Jose Luis, Gonzalez, Yolanda, Martínez-Robles, Luis, Ventura-Ayala, María Laura, Sadowinski-Pine, Stanislaw, Nava-Frías, Margarita, Moreno-Espinosa, Sarbelio, Casanova, Jean-Laurent, Puel, Anne, Boisson-Dupuis, Stephanie, Torres, Martha

“…In humans, recessive loss-of-function mutations in are associated with mycobacterial and viral infections, whereas gain-of-function (GOF) mutations in are…”
Get full text

Sweat conductivity and chloride titration for cystic fibrosis diagnosis in 3834 subjects by Lezana, José Luis, Vargas, Mario H., Karam-Bechara, José, Aldana, Ruth S., Furuya, María E.Y.

“…Sweat test is the standard for cystic fibrosis (CF) diagnosis. Conductivity is an alternative method not yet approved, in spite of its good correlation with…”
Get full text

Influence of SNPs in Genes that Modulate Lung Disease Severity in a Group of Mexican Patients with Cystic Fibrosis by Yokoyama, Emiy, Chávez-Saldaña, Margarita, Orozco, Lorena, Cuevas, Francisco, Lezana, José Luis, Vigueras-Villaseñor, Rosa María, Rojas-Castañeda, Julio Cesar, Landero, Daniel Adrian

“…The variation in cystic fibrosis (CF) lung disease not always is explained by the CFTR genotype, so it has become apparent that modifier genes must play a…”
Get full text

Clinical Disease Caused by Klebsiella in 2 Unrelated Patients With Interleukin 12 Receptor beta 1 Deficiency by Pedraza, Sigifredo, Lezana, Jose Luis, Samarina, Arina, Aldana, Ruth, Herrera, Maria Teresa, Boisson-Dupuis, Stephanie, Bustamante, Jacinta, Pages, Perle, Casanova, Jean-Laurent, Picard, Capucine

“…Patients with interleukin 12 (IL-12)p40 or IL-12 receptor beta 1 (IL12R beta 1) deficiencies are prone to develop infections caused by mycobacteria and…”
Get full text

Pseudomonas Aeruginosa: Genetic Adaptation, A Strategy for its Persistence in Cystic Fibrosis by Rosales-Reyes, Roberto, Vargas-Roldán, Silvia Yalid, Lezana-Fernández, José Luis, Santos-Preciado, José Ignacio

“…Cystic fibrosis (CF) is a progressive autosomal recessive genetic disease that principally affects the respiratory and digestive systems. It is a chronic…”
Get full text

Significance of Molecular Identification of Genomic Variants of Pseudomonas aeruginosa in Children with Cystic Fibrosis by Rosales-Reyes, Roberto, Flores-Vega, Verónica Roxana, Lezana-Fernández, José Luis, Santos-Preciado, José Ignacio

“…Pseudomonas aeruginosa is a significant cause of lung infections in patients with cystic fibrosis (CF). Pseudomonas produces a chronic infection that increases…”
Get full text

Effect of the Complex Allele p.[Ile148Thr;Ile1023_Val1024del] in Cystic Fibrosis and Tracing of a Founder Effect in Mexican Families by Mendiola-Vidal, Namibia Guadalupe, Contreras-Cubas, Cecilia, Barajas-Olmos, Francisco, Villafan-Bernal, José Rafael, Yañez-Felix, Ana Lucia, García-Ortiz, Humberto, Centeno-Cruz, Federico, Mendoza-Caamal, Elvia, Alaez-Verson, Carmen, Jiménez-Ruíz, Juan Luis, Monge-Cázares, Tulia, Lieberman, Esther, Baca, Vicente, Lezana, José Luis, Martínez-Hernández, Angélica, Orozco, Lorena

“…Cystic fibrosis (CF) is a rare autosomal recessive disease most commonly affecting the Caucasian population. CF diagnosis can be a challenge due to the large…”
Get full text

Mendelian Susceptibility to Mycobacterial Disease: Retrospective Clinical and Genetic Study in Mexico by Peñafiel Vicuña, Ana Karen, Yamazaki Nakashimada, Marco, León Lara, Ximena, Mendieta Flores, Elizabeth, Nuñez Núñez, María Enriqueta, Lona-Reyes, Juan Carlos, Hernández Nieto, Leticia, Ramírez Vázquez, María Guadalupe, Barroso Santos, Joel, López Iñiguez, Álvaro, González, Yolanda, Torres, Martha, Lezana Fernández, José Luis, Román Montes, Carla M., Medina-Torres, Edgar Alejandro, González Serrano, Edith, Bustamante Ogando, Juan Carlos, Lugo Reyes, Saúl, Zavaleta Martínez, Oscar, Staines Boone, Aidé Tamara, Venegas Montoya, Edna, Aguilar Gómez, Nancy Evelyn, Soudeé, Camille, Jouanguy, Emmanuelle, Puel, Anne, Boisson-Dupuis, Stéphanie, Pedraza Sánchez, Sigifredo, Casanova, Jean-Laurent, Espinosa Rosales, Francisco, Espinosa Padilla, Sara, Bustamante, Jacinta, Blancas Galicia, Lizbeth

“…Mendelian susceptibility to mycobacterial disease (MSMD) is a rare genetic disorder characterized by impaired immunity against intracellular pathogens, such as…”
Get full text

Genotype-phenotype correlation in a sample of Mexican patients with cystic fibrosis by Yokoyama, Emiy, Lezana, José Luis, Vigueras-Villaseñor, Rosa María, Rojas-Castañeda, Julio, Saldaña-Álvarez, Yolanda, Orozco, Lorena, Chávez-Saldaña, Margarita

“…Cystic fibrosis is a lethal autosomal recessive disease, commonly seen in Caucasian population. The World Health Organization (WHO) estimated that in Mexico,…”
Get full text

CFTR allelic heterogeneity in Mexican patients with cystic fibrosis: implications for molecular screening by Chávez-Saldaña, Margarita, Yokoyama, Emiy, Lezana, José Luis, Carnevale, Alessandra, Macías, Miguel, Vigueras, Rosa M, López, Marisol, Orozco, Lorena

“…Cystic fibrosis, the most common autosomal recessive disorder, is caused by defects in the CF transmembrane conductance regulator gene (CFTR) that encodes a…”
Get full text

Mycobacterium infection in a pediatric patient with immunodeficiency by gain of function mutation in STAT1 by Luis, Martínez-Robles, Laura, Ventura-Ayala, Margarita, Navas-Frias, José Luis, Lezana-Fernández, Yolanda, González-Hernández, Martha, Torres, Stephanie, Boisson-Dupuis, Jean-Laurent, Casanova, Sigifredo, Pedraza-Sanchez

“…Abstract only…”
Get full text

Clinical Features of Candidiasis in Patients With Inherited Interleukin 12 Receptor β1 Deficiency by Ouederni, Monia, Sanal, Ozden, Ikincioğullari, Aydan, Tezcan, Ilhan, Dogu, Figen, Sologuren, Ithaisa, Pedraza-Sánchez, Sigifredo, Keser, Melike, Tanir, Gonul, Nieuwhof, Chris, Colino, Elena, Kumararatne, Dinakantha, Levy, Jacov, Kutukculer, Necil, Aytekin, Caner, Herrera-Ramos, Estefanía, Bhatti, Micah, Karaca, Neslihan, Barbouche, Ridha, Broides, Arnon, Goudouris, Ekaterini, Franco, José Luis, Parvaneh, Nima, Reisli, Ismail, Strickler, Alexis, Shcherbina, Anna, Somer, Ayper, Segal, Anthony, Angel-Moreno, Alfonso, Lezana-Fernandez, José Luis, Bejaoui, Mohamed, Valle, Miriam Bobadilla-Del, Kachboura, Salem, Sentongo, Timothy, Ben-Mustapha, Imen, Bustamante, Jacinta, Picard, Capucine, Puel, Anne, Boisson-Dupuis, Stéphanie, Abel, Laurent, Casanova, Jean-Laurent, Rodríguez-Gallego, Carlos

“…Owing to impaired interleukin 17 immunity, interleukin 12βR1 (IL-12βR1)–deficient patients have mucocutaneous candidiasis, which is usually recurrent or…”
Get full text

Emergence of GES-19-producing Pseudomonas aeruginosa exoU+ belonging to the global high-risk clone ST235 in cystic fibrosis infection by Rosales-Reyes, Roberto, Esposito, Fernanda, Fontana, Herrison, Lezana-Fernández, José Luis, Lascurain, Ricardo, De la Cruz, Miguel A., Fuga, Bruna, Lincopan, Nilton, Santos-Preciado, José Ignacio

“…The emergence of high-risk clones of priority pathogens exhibiting convergence of antimicrobial resistance and virulence is a critical issue worldwide. In a…”
Get full text

Pseudomonas aeruginosa Isolates From a Cohort of Mexican Children With Cystic Fibrosis Show Adaptation to a Chronic Phenotype by Rosales-Reyes, Roberto, Rodríguez-Alvarado, Marian, Lezana-Fernández, José Luis, Sánchez-Lozano, Joselin Yleana, Gayosso-Vázquez, Catalina, Jarillo-Quijada, Ma Dolores, Toledano-Tableros, José Eduardo, Arredondo-Mercado, Martha Jimena, Alcántar-Curiel, María Dolores, Lincopan, Nilton, Vidal, Jorge E., Lascurain, Ricardo, Valvano, Miguel A., Santos-Preciado, José Ignacio

“…BACKGROUND:Long-term persistence of Pseudomonas aeruginosa in the lung of individuals with cystic fibrosis (CF) is associated with progressive selection of…”
Get full text

Clinical Disease Caused by Klebsiella in 2 Unrelated Patients With Interleukin 12 Receptor β1 Deficiency by Pedraza, Sigifredo, Lezana, Jose Luis, Samarina, Arina, Aldana, Ruth, Herrera, Maria Teresa, Boisson-Dupuis, Stéphanie, Bustamante, Jacinta, Pages, Perle, Casanova, Jean-Laurent, Picard, Capucine

“…Patients with interleukin 12 (IL-12)p40 or IL-12 receptor β1 (IL12Rβ1) deficiencies are prone to develop infections caused by mycobacteria and salmonella;…”
Get full text