Search Results - "Leypoldt, Frank"

Autoimmune encephalopathies by Leypoldt, Frank, Armangue, Thaís, Dalmau, Josep

“…Over the past 10 years, the continual discovery of novel forms of encephalitis associated with antibodies to cell‐surface or synaptic proteins has changed the…”
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Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study by Gresa-Arribas, Nuria, PhD, Titulaer, Maarten J, MD, Torrents, Abiguei, BS, Aguilar, Esther, McCracken, Lindsey, MPH, Leypoldt, Frank, MD, Gleichman, Amy J, PhD, Balice-Gordon, Rita, Prof, Rosenfeld, Myrna R, Prof, Lynch, David, Prof, Graus, Francesc, Prof, Dalmau, Josep, Prof

“…Summary Background Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a severe but treatable autoimmune disorder which diagnosis depends on sensitive…”
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Autoimmune encephalitis as differential diagnosis of infectious encephalitis by Armangue, Thaís, Leypoldt, Frank, Dalmau, Josep

“…This review describes the main types of autoimmune encephalitis with special emphasis on those associated with antibodies against neuronal cell surface or…”
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The clinical spectrum of Caspr2 antibody–associated disease by van Sonderen, Agnes, Ariño, Helena, Petit-Pedrol, Mar, Leypoldt, Frank, Körtvélyessy, Peter, Wandinger, Klaus-Peter, Lancaster, Eric, Wirtz, Paul W, Schreurs, Marco W.J, Sillevis Smitt, Peter A.E, Graus, Francesc, Dalmau, Josep, Titulaer, Maarten J

“…OBJECTIVE:To report a large cohort of patients with antibodies against contactin-associated protein-like 2 (Caspr2) and provide the clinical spectrum of this…”
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Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes by Graus, Francesc, Vogrig, Alberto, Muñiz-Castrillo, Sergio, Antoine, Jean-Christophe G., Desestret, Virginie, Dubey, Divyanshu, Giometto, Bruno, Irani, Sarosh R., Joubert, Bastien, Leypoldt, Frank, McKeon, Andrew, Prüss, Harald, Psimaras, Dimitri, Thomas, Laure, Titulaer, Maarten J., Vedeler, Christian A., Verschuuren, Jan J., Dalmau, Josep, Honnorat, Jerome

“…The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs) requires an increasing understanding of their clinical, immunologic, and oncologic…”
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Overlapping demyelinating syndromes and anti-N-methyl-D-aspartate receptor encephalitis by Titulaer, Maarten J., Höftberger, Romana, Iizuka, Takahiro, Leypoldt, Frank, McCracken, Lindsey, Cellucci, Tania, Benson, Leslie A., Shu, Huidy, Irioka, Takashi, Hirano, Makito, Singh, Gagandeep, Cobo Calvo, Alvaro, Kaida, Kenichi, Morales, Pamela S., Wirtz, Paul W., Yamamoto, Tomotaka, Reindl, Markus, Rosenfeld, Myrna R., Graus, Francesc, Saiz, Albert, Dalmau, Josep

“…Objective To report the clinical, radiological, and immunological association of demyelinating disorders with anti–N‐methyl‐D‐aspartate receptor (NMDAR)…”
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Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease by Bader, Jakob M, Geyer, Philipp E, Müller, Johannes B, Strauss, Maximilian T, Koch, Manja, Leypoldt, Frank, Koertvelyessy, Peter, Bittner, Daniel, Schipke, Carola G, Incesoy, Enise I, Peters, Oliver, Deigendesch, Nikolaus, Simons, Mikael, Jensen, Majken K, Zetterberg, Henrik, Mann, Matthias

“…Neurodegenerative diseases are a growing burden, and there is an urgent need for better biomarkers for diagnosis, prognosis, and treatment efficacy. Structural…”
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Structural Hippocampal Damage Following Anti- N -Methyl-D-Aspartate Receptor Encephalitis by Finke, Carsten, Kopp, Ute A, Pajkert, Anna, Behrens, Janina R, Leypoldt, Frank, Wuerfel, Jens T, Ploner, Christoph J, Prüss, Harald, Paul, Friedemann

“…Abstract Background The majority of patients with anti- N -methyl-D-aspartate receptor (NMDAR) encephalitis suffer from persistent memory impairment despite…”
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Herpes simplex virus encephalitis is a trigger of brain autoimmunity by Armangue, Thaís, Leypoldt, Frank, Málaga, Ignacio, Raspall-Chaure, Miquel, Marti, Itxaso, Nichter, Charles, Pugh, John, Vicente-Rasoamalala, Monica, Lafuente-Hidalgo, Miguel, Macaya, Alfons, Ke, Michael, Titulaer, Maarten J., Höftberger, Romana, Sheriff, Heather, Glaser, Carol, Dalmau, Josep

“…In 5 prospectively diagnosed patients with relapsing post–herpes simplex encephalitis (HSE), N‐methyl‐D‐aspartate receptor (NMDAR) antibodies were identified…”
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Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke by GELDERBLOM, Mathias, LEYPOLDT, Frank, MAGNUS, Tim, STEINBACH, Karin, BEHRENS, Doerthe, CHOE, Chi-Un, SILER, Dominic A, ARUMUGAM, Thiruma V, ORTHEY, Ellen, GERLOFF, Christian, TOLOSA, Eva

“…Ischemic stroke leads to significant morbidity and mortality in the Western world. Early reperfusion strategies remain the treatment of choice but can initiate…”
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Mechanisms of Autoantibody-Induced Pathology by Ludwig, Ralf J, Vanhoorelbeke, Karen, Leypoldt, Frank, Kaya, Ziya, Bieber, Katja, McLachlan, Sandra M, Komorowski, Lars, Luo, Jie, Cabral-Marques, Otavio, Hammers, Christoph M, Lindstrom, Jon M, Lamprecht, Peter, Fischer, Andrea, Riemekasten, Gabriela, Tersteeg, Claudia, Sondermann, Peter, Rapoport, Basil, Wandinger, Klaus-Peter, Probst, Christian, El Beidaq, Asmaa, Schmidt, Enno, Verkman, Alan, Manz, Rudolf A, Nimmerjahn, Falk

“…Autoantibodies are frequently observed in healthy individuals. In a minority of these individuals, they lead to manifestation of autoimmune diseases, such as…”
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Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke by Gelderblom, Mathias, Weymar, Anna, Bernreuther, Christian, Velden, Joachim, Arunachalam, Priyadharshini, Steinbach, Karin, Orthey, Ellen, Arumugam, Thiruma V., Leypoldt, Frank, Simova, Olga, Thom, Vivien, Friese, Manuel A., Prinz, Immo, Hölscher, Christoph, Glatzel, Markus, Korn, Thomas, Gerloff, Christian, Tolosa, Eva, Magnus, Tim

“…The devastating effect of ischemic stroke is attenuated in mice lacking conventional and unconventional T cells, suggesting that inflammation enhances tissue…”
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Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease by Leypoldt, Frank, Buchert, Ralph, Kleiter, Ingo, Marienhagen, Jörg, Gelderblom, Mathias, Magnus, Tim, Dalmau, Josep, Gerloff, Christian, Lewerenz, Jan

“…BackgroundPatients with encephalitis associated with antibodies against N-methyl-D-aspartate-receptor antibody (NMDAR-ab) encephalitis frequently show…”
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Functional and structural brain changes in anti-N-methyl-D-aspartate receptor encephalitis by Finke, Carsten, Kopp, Ute A., Scheel, Michael, Pech, Luisa-Maria, Soemmer, Carina, Schlichting, Jeremias, Leypoldt, Frank, Brandt, Alexander U., Wuerfel, Jens, Probst, Christian, Ploner, Christoph J., Prüss, Harald, Paul, Friedemann

“…Objective Anti–N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis is an autoimmune encephalitis with a characteristic neuropsychiatric syndrome and severe and…”
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Clinical features, prognostic factors, and antibody effects in anti-mGluR1 encephalitis by Spatola, Marianna, Petit Pedrol, Mar, Maudes, Estibaliz, Simabukuro, Mateus, Muñiz-Castrillo, Sergio, Pinto, Anne-Laurie, Wandinger, Klaus-Peter, Spiegler, Juliane, Schramm, Peter, Dutra, Lívia Almeida, Iorio, Raffaele, Kornblum, Cornelia, Bien, Christian G., Höftberger, Romana, Leypoldt, Frank, Titulaer, Maarten J., Sillevis Smitt, Peter, Honnorat, Jérôme, Rosenfeld, Myrna R., Graus, Francesc, Dalmau, Josep

“…OBJECTIVETo clinically characterize patients with anti-metabotropic glutamate receptor (mGluR) 1 encephalitis, to identify prognostic factors, and to study the…”
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Antibodies to the Caspr1/contactin-1 complex in chronic inflammatory demyelinating polyradiculoneuropathy by Pascual-Goñi, Elba, Fehmi, Janev, Lleixà, Cinta, Martín-Aguilar, Lorena, Devaux, Jérôme, Höftberger, Romana, Delmont, Emilien, Doppler, Kathrin, Sommer, Claudia, Radunovic, Aleksandar, Carvajal, Alejandra, Smyth, Shane, Williams, Laura, Mazanec, Radim, Potočková, Veronika, Hinds, Nigel, Cassereau, Julien, Viala, Karine, Lefilliatre, Mathilde, Nicolas, Guillaume, Foley, Peter, Leypoldt, Frank, Keddie, Stephen, Lunn, Michael P, Zimprich, Fritz, Nunkoo, Vharoon Sharma, Löscher, Wolfgang N, Martínez-Martínez, Laura, Díaz-Manera, Jordi, Rojas-Garcia, Ricard, Illa, Isabel, Rinaldi, Simon, Querol, Luis

“…Previous studies have described the clinical, serological and pathological features of patients with chronic inflammatory demyelinating polyradiculoneuropathy…”
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Common Denominators in the Immunobiology of IgG4 Autoimmune Diseases: What Do Glomerulonephritis, Pemphigus Vulgaris, Myasthenia Gravis, Thrombotic Thrombocytopenic Purpura and Autoimmune Encephalitis Have in Common? by Koneczny, Inga, Yilmaz, Vuslat, Lazaridis, Konstantinos, Tzartos, John, Lenz, Tobias L, Tzartos, Socrates, Tüzün, Erdem, Leypoldt, Frank

“…IgG4 autoimmune diseases (IgG4-AID) are an emerging group of autoimmune diseases that are caused by pathogenic autoantibodies of the IgG4 subclass. It has only…”
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Active Case Finding of Current Bornavirus Infections in Human Encephalitis Cases of Unknown Etiology, Germany, 2018-2020 by Eisermann, Philip, Rubbenstroth, Dennis, Cadar, Daniel, Thomé-Bolduan, Corinna, Eggert, Petra, Schlaphof, Alexander, Leypoldt, Frank, Stangel, Martin, Fortwängler, Thorsten, Hoffmann, Florian, Osterman, Andreas, Zange, Sabine, Niller, Hans-Helmut, Angstwurm, Klemens, Pörtner, Kirsten, Frank, Christina, Wilking, Hendrik, Beer, Martin, Schmidt-Chanasit, Jonas, Tappe, Dennis

“…Human bornavirus encephalitis is a severe and often fatal infection caused by variegated squirrel bornavirus 1 (VSBV-1) and Borna disease virus 1 (BoDV-1). We…”
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B-cell-depletion reverses dysbiosis of the microbiome in multiple sclerosis patients by Troci, Alba, Zimmermann, Olga, Esser, Daniela, Krampitz, Paula, May, Sandra, Franke, Andre, Berg, Daniela, Leypoldt, Frank, Stürner, Klarissa Hanja, Bang, Corinna

“…To elucidate cross-sectional patterns and longitudinal changes of oral and stool microbiota in multiple sclerosis (MS) patients and the effect of B-cell…”
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Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients by Jarius, Sven, Lechner, Christian, Wendel, Eva M, Baumann, Matthias, Breu, Markus, Schimmel, Mareike, Karenfort, Michael, Marina, Adela Della, Merkenschlager, Andreas, Thiels, Charlotte, Blaschek, Astrid, Salandin, Michela, Leiz, Steffen, Leypoldt, Frank, Pschibul, Alexander, Hackenberg, Annette, Hahn, Andreas, Syrbe, Steffen, Strautmanis, Jurgis, Häusler, Martin, Krieg, Peter, Eisenkölbl, Astrid, Stoffels, Johannes, Eckenweiler, Matthias, Ayzenberg, Ilya, Haas, Jürgen, Höftberger, Romana, Kleiter, Ingo, Korporal-Kuhnke, Mirjam, Ringelstein, Marius, Ruprecht, Klemens, Siebert, Nadja, Schanda, Kathrin, Aktas, Orhan, Paul, Friedemann, Reindl, Markus, Wildemann, Brigitte, Rostásy, Kevin

“…New-generation, cell-based assays have demonstrated a robust association of serum autoantibodies to full-length human myelin oligodendrocyte glycoprotein…”
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