Search Results - "Ley, Marie"

Routine use of MSI testing in colorectal cancer using a proposed algorithm by Ringgaard, Marie Ley, Steiniche, Torben, Krag, Søren Palmelund

“…Fifteen percent of all colorectal cancers have detectable defects in the mismatch repair system (dMMR). MMR status is used to identify possible Lynch Syndrome…”
Get full text

Membranes prime the RapGEF EPAC1 to transduce cAMP signaling by Sartre, Candice, Peurois, François, Ley, Marie, Kryszke, Marie-Hélène, Zhang, Wenhua, Courilleau, Delphine, Fischmeister, Rodolphe, Ambroise, Yves, Zeghouf, Mahel, Cianferani, Sarah, Ferrandez, Yann, Cherfils, Jacqueline

“…EPAC1, a cAMP-activated GEF for Rap GTPases, is a major transducer of cAMP signaling and a therapeutic target in cardiac diseases. The recent discovery that…”
Get full text

Pericardial Cyst: Cause of Sudden Cardiac Death? by Ley, Marie Brix, Larsen, Maiken Kudahl

“…Cardiovascular disease is the leading cause of sudden death in the world. The etiology of sudden cardiac death involves a wide range of diseases, but seldom…”
Get full text

Pushing the limits of native MS: Online SEC-native MS for structural biology applications by Deslignière, Evolène, Ley, Marie, Bourguet, Maxime, Ehkirch, Anthony, Botzanowski, Thomas, Erb, Stéphane, Hernandez-Alba, Oscar, Cianférani, Sarah

“…Native mass spectrometry (nMS) is now widely applied to investigate non-covalently assembled biomolecule complexes. nMS requires the use of near-neutral pH and…”
Get full text

Bioorthogonal Monomycolate of Trehalose Disclosed the O‑Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in C. glutamicum by Labarre, Cécile, Zhang, Yijie, Lesur, Emilie, Ley, Marie, Sago, Laila, Dietrich, Christiane, de Sousa-d’Auria, Célia, Constantinesco-Becker, Florence, Baron, Aurélie, Doisneau, Gilles, Urban, Dominique, Chevreux, Guillaume, Guianvarc’h, Dominique, Bourdreux, Yann, Bayan, Nicolas

“…Protein mycoloylation is a recently identified unusual post-translational modification (PTM) exclusively observed in Mycobacteriales, an order of bacteria that…”
Get full text

Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases by Dos Santos Morais, Raphael, Santo, Paulo E., Ley, Marie, Schelcher, Cédric, Abel, Yoann, Plassart, Laura, Deslignière, Evolène, Chagot, Marie-Eve, Quinternet, Marc, Paiva, Ana C.F., Hessmann, Steve, Morellet, Nelly, M. F. Sousa, Pedro, Vandermoere, Franck, Bertrand, Edouard, Charpentier, Bruno, Bandeiras, Tiago M., Plisson-Chastang, Célia, Verheggen, Céline, Cianférani, Sarah, Manival, Xavier

“…[Display omitted] •DPCD is a new RUVBL1/RUVBL2 cofactor.•3 DPCD interact with 1 RUVBL1/RUVBL2 heterohexamer with sub-micromolar affinity.•DPCD regulates the…”
Get full text