Search Results - "Lewis, Simon J.G."

Current Treatment Options for Alzheimer's Disease and Parkinson's Disease Dementia by Szeto, Jennifer Y Y, Lewis, Simon J G

“…Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common neurodegenerative disorders encountered in clinical practice. Whilst dementia has…”
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A pathophysiological model of freezing of gait in Parkinson's disease by Lewis, Simon J.G, Barker, Roger A

“…Abstract Freezing of gait (FOG) is a common phenomenon in Parkinson's disease (PD) affecting over half of those in the advanced stages of the disease and often…”
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A comparison of clinical and objective measures of freezing of gait in Parkinson's disease by Morris, Tiffany R, Cho, Catherine, Dilda, Valentina, Shine, James M, Naismith, Sharon L, Lewis, Simon J.G, Moore, Steven T

“…Abstract Freezing of gait, a paroxysmal motor block, is common in the latter stages of Parkinson's disease. The current 'gold standard' of assessing the…”
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Using virtual reality to explore the role of conflict resolution and environmental salience in Freezing of Gait in Parkinson's disease by Matar, Elie, Shine, James M, Naismith, Sharon L, Lewis, Simon J.G

“…Abstract Background The freezing phenomenon is among the most disabling symptoms of Parkinson's disease (PD) manifesting most commonly as Freezing of Gait with…”
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Assessing the utility of the Movement Disorder Society Task Force Level 1 diagnostic criteria for mild cognitive impairment in Parkinson's disease by Szeto, Jennifer Y.Y, Mowszowski, Loren, Gilat, Moran, Walton, Courtney C, Naismith, Sharon L, Lewis, Simon J.G

“…Abstract Background Using the Movement Disorder Society (MDS) Task Force Level 1 criteria, this study examined the classification of mild cognitive impairment…”
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Cognitive impairment with and without depression history: an analysis of white matter microstructure by Duffy, Shantel L., MDR (Hons), Paradise, Matt, FRANZCP, Hickie, Ian B., FRANZCP, Lewis, Simon J.G., FRACP, Naismith, Sharon L., DPsych, Lagopoulos, Jim, PhD

“…Background Mild cognitive impairment (MCI) and late-life depression are clinical syndromes that often co-occur and may represent an early manifestation of…”
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Dementia with Lewy bodies research consortia: A global perspective from the ISTAART Lewy Body Dementias Professional Interest Area working group by D'Antonio, Fabrizia, Kane, Joseph P.M., Ibañez, Agustin, Lewis, Simon J.G., Camicioli, Richard, Wang, Huali, Yu, Yueyi, Zhang, Jing, Ji, Yong, Borda, Miguel Germán, Kandadai, Rukmini Mridula, Babiloni, Claudio, Bonanni, Laura, Ikeda, Manabu, Boeve, Bradley F., Leverenz, James B., Aarsland, Dag

“…Dementia with Lewy bodies (DLB) research has seen a significant growth in international collaboration over the last three decades. However, researchers face a…”
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Research criteria for the diagnosis of prodromal dementia with Lewy bodies by McKeith, Ian G., Ferman, Tanis J., Thomas, Alan J., Blanc, Frédéric, Boeve, Bradley F., Fujishiro, Hiroshige, Kantarci, Kejal, Muscio, Cristina, O'Brien, John T., Postuma, Ronald B., Aarsland, Dag, Ballard, Clive, Bonanni, Laura, Donaghy, Paul, Emre, Murat, Galvin, James E., Galasko, Douglas, Goldman, Jennifer G., Gomperts, Stephen N., Honig, Lawrence S., Ikeda, Manabu, Leverenz, James B., Lewis, Simon J.G., Marder, Karen S., Masellis, Mario, Salmon, David P., Taylor, John Paul, Tsuang, Debby W., Walker, Zuzana, Tiraboschi, Pietro

“…The prodromal phase of dementia with Lewy bodies (DLB) includes (1) mild cognitive impairment (MCI), (2) delirium-onset, and (3) psychiatric-onset…”
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Clinical and methodological challenges for assessing freezing of gait: Future perspectives by Mancini, Martina, Bloem, Bastiaan R., Horak, Fay B., Lewis, Simon J.G., Nieuwboer, Alice, Nonnekes, Jorik

“…Freezing of gait, defined as sudden and usually brief episodes of inability to produce effective stepping, often results in falls and is both disabling and…”
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Cognitive training in Parkinson disease: A systematic review and meta-analysis by Leung, Isabella H.K, Walton, Courtney C, Hallock, Harry, Lewis, Simon J.G, Valenzuela, Michael, Lampit, Amit

“…OBJECTIVE:To quantify the effects of cognitive training (CT) on cognitive and behavioral outcome measures in patients with Parkinson disease (PD). METHODS:We…”
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Visual Hallucinations and the Role of Medications in Parkinson’s Disease: Triggers, Pathophysiology, and Management by Powell, Alice, Ireland, Catriona, Lewis, Simon J.G

“…Visual hallucinations, which are part of the syndrome of Parkinson’s disease (PD) psychosis, affect patients’ quality of life and increase the likelihood of…”
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Dysfunctional Limbic Circuitry Underlying Freezing of Gait in Parkinson’s Disease by Gilat, Moran, Ehgoetz Martens, Kaylena A., Miranda-Domínguez, Oscar, Arpan, Ishu, Shine, James M., Mancini, Martina, Fair, Damien A., Lewis, Simon J.G., Horak, Fay B.

“…•FOG in PD is associated with increased resting-state connectivity between the amygdala and putamen.•FOG in PD is associated with anti-coupling between the…”
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LRRK2‐mediated Rab10 phosphorylation in immune cells from Parkinson's disease patients by Atashrazm, Farzaneh, Hammond, Deborah, Perera, Gayathri, Bolliger, Marc F., Matar, Elie, Halliday, Glenda M., Schüle, Birgitt, Lewis, Simon J.G., Nichols, R. Jeremy, Dzamko, Nicolas

“…Background Leucine‐rich repeat kinase 2 is a potential therapeutic target for the treatment of Parkinson's disease, and clinical trials of leucine‐rich repeat…”
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Structural brain correlates of obstructive sleep apnoea in older adults at risk for dementia by Cross, Nathan E, Memarian, Negar, Duffy, Shantel L, Paquola, Casey, LaMonica, Haley, D'Rozario, Angela, Lewis, Simon J G, Hickie, Ian B, Grunstein, Ronald R, Naismith, Sharon L

“…This study aimed to investigate associations between obstructive sleep apnoea (OSA) and cortical thickness in older adults with subjective and objective…”
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Dopamine depletion impairs gait automaticity by altering cortico-striatal and cerebellar processing in Parkinson's disease by Gilat, Moran, Bell, Peter T., Ehgoetz Martens, Kaylena A., Georgiades, Matthew J., Hall, Julie M., Walton, Courtney C., Lewis, Simon J.G., Shine, James M.

“…Impairments in motor automaticity cause patients with Parkinson's disease to rely on attentional resources during gait, resulting in greater motor variability…”
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Predicting the onset of freezing of gait: A longitudinal study by Ehgoetz Martens, Kaylena A., Lukasik, Emily L., Georgiades, Matthew J., Gilat, Moran, Hall, Julie M., Walton, Courtney C., Lewis, Simon J.G.

“…ABSTRACT Background: Freezing of gait is a disabling symptom of Parkinson's disease that ultimately affects approximately 80% of patients, yet very little…”
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Effects of STN/SNr deep brain stimulation in a case of progressive supranuclear palsy with a Parkinson disease phenotype by Shepherd, Claire E, Lewis, Simon J G, Tisch, Stephen, McCann, Heather, Jonker, Ben, Halliday, Glenda M

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Tricks of the mind: Visual hallucinations as disorders of attention by Shine, James M, O'Callaghan, Claire, Halliday, Glenda M, Lewis, Simon J G

“…Visual hallucinations are common across a number of disorders but to date, a unifying pathophysiology underlying these phenomena has not been described. In…”
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Addressing the Challenges of Clinical Research for Freezing of Gait in Parkinson's Disease by Lewis, Simon J.G., Factor, Stewart A., Giladi, Nir, Hallett, Mark, Nieuwboer, Alice, Nutt, John G., Przedborski, Serge, Papa, Stella M.

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Discussion of Research Priorities for Gait Disorders in Parkinson's Disease by Bohnen, Nicolaas I., Costa, Rui M., Dauer, William T., Factor, Stewart A., Giladi, Nir, Hallett, Mark, Lewis, Simon J.G., Nieuwboer, Alice, Nutt, John G., Takakusaki, Kaoru, Kang, Un Jung, Przedborski, Serge, Papa, Stella M.

“…ABSTRACT Gait and balance abnormalities develop commonly in Parkinson's disease and are among the motor symptoms most disabling and refractory to dopaminergic…”
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