Search Results - "Lewis, Michael I"
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Clinical trial design and new therapies for pulmonary arterial hypertension
Published in The European respiratory journal (01-01-2019)“…Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on case reports and small series, and was largely ineffectual. As a deeper…”
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Therapeutic benefits of intravenous cardiosphere-derived cell therapy in rats with pulmonary hypertension
Published in PloS one (24-08-2017)“…Pulmonary arterial hypertension (PAH) is a progressive condition characterized by occlusive pulmonary arteriopathy, in which survival remains poor despite…”
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3
Metabolic and morphometric profile of muscle fibers in chronic hemodialysis patients
Published in Journal of applied physiology (1985) (01-01-2012)“…Muscle weakness and effort intolerance are common in maintenance hemodialysis (MHD) patients. This study characterized morphometric, histochemical, and…”
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4
Severe Nonspecific Interstitial Pneumonia (NSIP) in an Adolescent
Published in Case reports in pulmonology (2022)“…Childhood interstitial lung disease (chILD) is remarkably rare with a reported prevalence from 0.13 per 100,000 children under 17 years to 16.2 per 100,000…”
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Time course expression of Foxo transcription factors in skeletal muscle following corticosteroid administration
Published in Journal of applied physiology (1985) (01-01-2010)“…1 Division of Pulmonary/Critical Care Medicine, The Burns and Allen Research Institute, Cedars-Sinai Medical Center; and ; 2 The David Geffen School of…”
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Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice
Published in JCI insight (06-06-2019)Get full text
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Evaluating the Right Ventricle in Acute and Chronic Pulmonary Embolism: Current and Future Considerations
Published in Seminars in respiratory and critical care medicine (01-04-2021)“…The right ventricle (RV), due to its morphologic and physiologic differences, is susceptible to sudden increase in RV afterload, as noted in patients with…”
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Effect of endurance and/or strength training on muscle fiber size, oxidative capacity, and capillarity in hemodialysis patients
Published in Journal of applied physiology (1985) (15-10-2015)“…We previously reported reduced limb muscle fiber succinate dehydrogenase (SDH) activity and capillarity density and increased cross-sectional areas (CSAs) of…”
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Exercise in maintenance hemodialysis patients induces transcriptional changes in genes favoring anabolic muscle
Published in Journal of the American Society of Nephrology (01-11-2007)Get full text
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10
Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice
Published in JCI insight (04-04-2019)“…Dystrophin deficiency leads to progressive muscle degeneration in Duchenne muscular dystrophy (DMD) patients. No known cure exists, and standard care relies on…”
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Insulin-like growth factor I prevents corticosteroid-induced diaphragm muscle atrophy in emphysematous hamsters
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-07-2003)“…The aim of this study was to evaluate whether recombinant human insulin-like growth factor I (rhIGF-I) could attenuate or prevent diaphragm (DIA) fiber atrophy…”
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Chronic Thromboembolic Pulmonary Hypertension: the Bedside
Published in Current cardiology reports (01-10-2021)“…Purpose of Review Chronic thromboembolic pulmonary hypertension (CTEPH), included in group 4 PH, is an uncommon complication of acute pulmonary embolism (PE),…”
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13
Effects of Testosterone and Resistance Training in Men with Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-10-2004)“…Dysfunction of the muscles of ambulation contributes to exercise intolerance in chronic obstructive pulmonary disease (COPD). Men with COPD have high…”
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Chronic Thromboembolic Pulmonary Hypertension: the Bench
Published in Current cardiology reports (01-10-2021)“…Purpose of Review Chronic thromboembolic pulmonary hypertension (CTEPH) is an uncommon complication of acute pulmonary embolism (PE), in which the red,…”
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15
The ALPHA phase 1 study: pulmonary ArteriaL hypertension treated with CardiosPHere-Derived allogeneic stem cells
Published in EBioMedicine (01-02-2024)“…Pulmonary Arterial Hypertension (PAH) is a progressive condition with no cure. Even with pharmacologic advances, survival remains poor. Lung pathology on PAH…”
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Cellular adaptations of skeletal muscles to cyclosporine
Published in Journal of applied physiology (1985) (01-06-1998)“…Division of Pulmonary/Critical Care Medicine, Department of Medicine, The Burns and Allen Research Institute, Cedars-Sinai Medical Center, and the University…”
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Skeletal muscle adaptations to testosterone and resistance training in men with COPD
Published in Journal of applied physiology (1985) (01-10-2007)“…Divisions of 1 Pulmonary and Critical Care Medicine and of 2 Endocrinology, Diabetes, and Metabolism, The Burns and Allen Research Institute at Cedars-Sinai…”
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Testosterone and resistance training effects on muscle nitric oxide synthase isoforms in COPD men
Published in Respiratory medicine (01-02-2012)“…Summary Background Skeletal muscle dysfunction contributes to exercise limitation in COPD. The role of the nitric oxide synthase (NOS) system in muscle…”
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Effects of malnutrition with or without eicosapentaenoic acid on proteolytic pathways in diaphragm
Published in Respiratory physiology & neurobiology (15-01-2012)“…Highlights ► Proteolytic pathways were studied in the malnourished (ND) diaphragm ± EPA treatment. ► EPA significantly reduced mRNA abundances for most genes…”
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Mechanisms underlying myogenesis: complex and likely to become more so
Published in Journal of applied physiology (1985) (01-12-2006)Get full text
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