Search Results - "Lewis, M.T"
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Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range of experimental nervous system disorders
Published in Neuroscience (15-09-2010)“…Abstract Glutamate neurotransmission is highly regulated, largely by glutamate transporters. In the spinal cord, the glutamate transporter GLT-1 is primarily…”
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Prevalence of pelvic organ prolapse detected at dynamic MRI in women without history of pelvic floor dysfunction: Comparison of two reference lines
Published in Clinical radiology (01-02-2014)“…Aim To retrospectively evaluate the prevalence of pelvic organ prolapse as an incidental finding on dynamic magnetic resonance imaging (MRI) using two…”
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Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats
Published in Neuroscience (29-12-2009)“…Abstract Spinal cord microglial toll-like receptor 4 (TLR4) has been implicated in enhancing neuropathic pain and opposing morphine analgesia. The present…”
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The Search for Hesperian Organic Matter on Mars: Pyrolysis Studies of Sediments Rich in Sulfur and Iron
Published in Astrobiology (01-04-2018)“…Jarosite on Mars is of significant geological and astrobiological interest, as it forms in acidic aqueous conditions that are potentially habitable for…”
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Recovery of Fatty Acids from Mineralogic Mars Analogs by TMAH Thermochemolysis for the Sample Analysis at Mars Wet Chemistry Experiment on the Curiosity Rover
Published in Astrobiology (01-04-2019)“…The Mars Curiosity rover carries a diverse instrument payload to characterize habitable environments in the sedimentary layers of Aeolis Mons. One of these…”
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P190A RhoGAP is required for mammary gland development
Published in Developmental biology (01-12-2011)“…P190A and p190B Rho GTPase activating proteins (GAPs) are essential genes that have distinct, but overlapping roles in the developing nervous system. Previous…”
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Ocular vaccinia infection in laboratory worker, Philadelphia, 2004
Published in Emerging infectious diseases (01-01-2006)“…We report a case of ocular vaccinia infection in an unvaccinated laboratory worker. The patient was infected by a unique strain used in an experiment performed…”
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Role of Minerals in Hydrogen Sulfide Generation during Steam-Assisted Recovery of Heavy Oil
Published in Energy & fuels (19-04-2018)“…Heavy oil is recovered from reservoirs using steam-assisted technology, which can lead to H2S generation if the oil is relatively sulfur-rich. We have used…”
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Would Targeting Increase Efficiency of Syphilis Partner Services Programs?—Data From New York City, Philadelphia, Texas, and Virginia
Published in Sexually transmitted diseases (01-06-2014)“…BACKGROUNDTargeted partner notification (PN), or limiting PN to groups in which efforts are most successful, has been suggested as a potentially cost-effective…”
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Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer
Published in Oncogene (12-03-2015)“…Signal transducer and activator of transcription (STAT) 3 regulates many cardinal features of cancer including cancer cell growth, apoptosis resistance, DNA…”
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Two Sides of the Same Coin: The Role of Developmental pathways and pluripotency factors in normal mammary stem cells and breast cancer metastasis
Published in Journal of mammary gland biology and neoplasia (01-06-2020)“…Breast cancer initiation and progression are often observed as the result of dysregulation of normal developmental processes and pathways. Studies focused on…”
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A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis
Published in Oncogene (12-06-2014)“…Dicer is an RNase III enzyme essential for the maturation of the majority of microRNAs. Recent studies have revealed downregulation or hemizygous loss of Dicer…”
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Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae
Published in Neuroscience (07-11-2014)“…Highlights • Adult rat CNS endothelial cells express functional TLR4. • The opioid receptor-inactive morphine metabolite M3G activates TLR4-dependent…”
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The Changing Spectrum of Clostridium Difficile –Associated Disease
Published in The Journal of the American Dental Association (1939) (2008)“…ABSTRACT Background Clostridium difficile is an anaerobic, spore-forming bacterium that causes a wide range of diseases of the gastrointestinal tract. It is…”
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The Changing Spectrum of Clostridium Difficile Associated Disease: Implications for Dentistry
Published in The Journal of the American Dental Association (1939) (01-01-2008)“…Clostridium difficile is an anaerobic, spore-forming bacterium that causes a wide range of diseases of the gastrointestinal tract. It is best known for its…”
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DNA repair signature is associated with anthracycline response in triple negative breast cancer patients
Published in Breast cancer research and treatment (01-08-2010)“…We hypothesized that a subset of sporadic triple negative (TN) breast cancer patients whose tumors have defective DNA repair similar to BRCA1-associated tumors…”
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Vaginal Microbiome and Its Relationship to Behavior, Sexual Health, and Sexually Transmitted Diseases
Published in Obstetrics and gynecology (New York. 1953) (01-04-2017)“…The vaginal microbiota has great significance in maintaining vaginal health and protecting the host from disease. Recent advances in molecular techniques and…”
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Sexually Transmitted Infections Among US Women and Men: Prevalence and Incidence Estimates, 2018
Published in Sexually transmitted diseases (01-04-2021)“…The most recent estimates of the number of prevalent and incident sexually transmitted infections (STIs) in the United States were for 2008. We provide updated…”
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Effectiveness of a serogroup B outer membrane vesicle meningococcal vaccine against gonorrhoea: a retrospective observational study
Published in The Lancet infectious diseases (01-07-2022)“…Declining antimicrobial susceptibility to current gonorrhoea antibiotic treatment and inadequate treatment options have raised the possibility of untreatable…”
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