Search Results - "Lewis, Kriste A."

Gender-specific effects of comorbid depression and anxiety on the propensity to drink in negative emotional states by Karpyak, Victor M., Biernacka, Joanna M., Geske, Jennifer R., Abulseoud, Osama A., Brunner, Michael D., Chauhan, Mohit, Hall-Flavin, Daniel K., Lewis, Kriste A., Loukianova, Larissa L., Melnyk, George J., Onsrud, David A., Proctor, Brian D., Schneekloth, Terry D., Skime, Michelle K., Wittkopp, John E., Frye, Mark A., Mrazek, David A.

“…Background and Aims Depression and anxiety are often comorbid with alcoholism and contribute to craving and relapse. We aimed to estimate the prevalence of…”
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S Phase and G2 Arrests Induced by Topoisomerase I Poisons Are Dependent on ATR Kinase Function by Cliby, William A, Lewis, Kriste A, Lilly, Kia K, Kaufmann, Scott H

“…ATR, a human phosphatidylinositol 3-kinase-related kinase, is an important component of the cellular response to DNA damage. In the present study, we evaluated…”
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Ataxia telangiectasia and rad3-related kinase contributes to cell cycle arrest and survival after cisplatin but not oxaliplatin by Lewis, Kriste A, Lilly, Kia K, Reynolds, Evelyn A, Sullivan, William P, Kaufmann, Scott H, Cliby, William A

“…The DNA cross-linking agents cisplatin and oxaliplatin are widely used in the treatment of human cancer. Lesions produced by these agents are widely known to…”
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Characteristics of Heart Rate Variability in Alcohol-Dependent Subjects and Nondependent Chronic Alcohol Users by Karpyak, Victor M., Romanowicz, Magdalena, Schmidt, John E., Lewis, Kriste A., Bostwick, John M.

“…Heart rate variability (HRV) is an objective and sensitive measure of integrated physiological functioning reflective of heart rhythm responsivity to internal…”
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Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states by Karpyak, Victor M., Winham, Stacey J., Preuss, Ulrich W., Zill, Peter, Cunningham, Julie M., Walker, Denise L., Lewis, Kriste A., Geske, Jennifer R., Colby, Colin L., Abulseoud, Osama A., Hall-Flavin, Daniel K., Loukianova, Larissa L., Schneekloth, Terry D., Frye, Mark A, Bazov, Igor, Heit, John A., Bakalkin, Georgy, Mrazek, David A., Biernacka, Joanna M.

“…Synthetic κ-opioid receptor (KOR) agonists induce dysphoric and pro-depressive effects and variations in the KOR (OPRK1) and prodynorphin (PDYN) genes have…”
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Müllerian inhibiting substance type II receptor (MISIIR): A novel, tissue-specific target expressed by gynecologic cancers by Bakkum-Gamez, Jamie N, Aletti, Giovanni, Lewis, Kriste A, Keeney, Gary L, Thomas, Bijoy M, Navarro-Teulon, Isabelle, Cliby, William A

“…Abstract Objective. Müllerian inhibiting substance type II receptor (MISIIR) is expressed by ovarian, breast, and prostate cancers [Masiakos PT, et al. Human…”
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Association of GATA4 sequence variation with alcohol dependence by Karpyak, Victor M., Winham, Stacey J., Biernacka, Joanna M., Cunningham, Julie M., Lewis, Kriste A., Geske, Jennifer R., Colby, Colin L., Abulseoud, Osama A., Hall-Flavin, Daniel K., Loukianova, Larissa L., Schneekloth, Terry D., Frye, Mark A., Heit, John A., Mrazek, David A.

“…To further explore reports of association of alcohol dependence and response to acamprosate treatment with the GATA4 rs13273672 single nucleotide polymorphism…”
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Heterozygous ATR mutations in mismatch repair-deficient cancer cells have functional significance by LEWIS, Kriste A, MULLANY, Sally, THOMAS, Bijoy, CHIEN, Jeremy, LOEWEN, Ralitsa, SHRIDHAR, Viji, CLIBY, William A

“…ATR (ataxia telangiectasia and Rad3-related) function is necessary for the proper response to commonly used chemotherapeutic agents. Heterozygous truncating…”
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Lovastatin alters the isoprenoid biosynthetic pathway in acute myelogenous leukemia cells in vivo by Lewis, Kriste A., Holstein, Sarah A., Hohl, Raymond J.

“…Lovastatin, a competitive inhibitor of hydroxymethylglutaryl coenzyme A reductase (HMGR), is used therapeutically to lower plasma cholesterol levels and has…”
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Mutations in the ataxia telangiectasia and rad3-related-checkpoint kinase 1 DNA damage response axis in colon cancers by Lewis, Kriste A., Bakkum-Gamez, Jamie, Loewen, Ralitsa, French, Amy J., Thibodeau, Stephen N., Cliby, William A.

“…In response to certain types of DNA damage, ataxia telangiectasia and rad3‐related (ATR) phosphorylates checkpoint kinase 1 (CHEK1) resulting in cell cycle…”
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A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days by BAILEY, Howard H, WILDING, George, LEWIS, Kriste A, HOHL, Raymond J, TUTSCH, Kendra D, ARZOOMANIAN, Rhoda Z, ALBERTI, Dona, FEIERABEND, Chris, SIMON, Kris, MARNOCHA, Rebecca, HOLSTEIN, Sarah A, STEWART, Jan

“…Perillyl alcohol (POH) has been shown to have both chemopreventative and chemotherapeutic activities in preclinical studies. The underlying mechanism(s) of…”
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Stereochemistry‐dependent inhibition of RAS farnesylation by farnesyl phosphonic acids by Hohl, Raymond J., Lewis, Kriste A., Cermak, Diana M., Wiemer, David F.

“…This investigation compares the effects of three farnesyl pyrophosphate analogs on selected aspects of isoprenoid metabolism. E,E‐α‐Hydroxyfarnesylphosphonate…”
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ATR CONTRIBUTES TO CELL CYCLE ARREST AND SURVIVAL AFTER CISPLATIN BUT NOT OXALIPLATIN1 by Lewis, Kriste A., Lilly, Kia K., Reynolds, Evelyn A., Sullivan, William P., Kaufmann, Scott H., Cliby, William A.

“…The DNA cross-linking agents cisplatin and oxaliplatin are widely used in the treatment of human cancer. Lesions produced by these agents are widely known to…”
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Modulation of RAS expression in human malignant cells by dietary supplements by Lewis, Kriste A., Hohl, Raymond J.

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