Search Results - "Lewis, Fred A."

A rotifer-derived paralytic compound prevents transmission of schistosomiasis to a mammalian host by Gao, Jiarong, Yang, Ning, Lewis, Fred A, Yau, Peter, Collins, 3rd, James J, Sweedler, Jonathan V, Newmark, Phillip A

“…Schistosomes are parasitic flatworms that infect over 200 million people, causing the neglected tropical disease, schistosomiasis. A single drug, praziquantel,…”
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Schistosomiasis by Tucker, Matthew S, Karunaratne, Laksiri B, Lewis, Fred A, Freitas, Tori C, Liang, Yung-San

“…Schistosomiasis is the second most important parasitic disease in the world in terms of public health impact. Globally, it is estimated that the disease…”
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Genetic manipulation of Schistosoma haematobium, the neglected schistosome by Rinaldi, Gabriel, Okatcha, Tunika I, Popratiloff, Anastas, Ayuk, Mary A, Suttiprapa, Sutas, Mann, Victoria H, Liang, Yung-san, Lewis, Fred A, Loukas, Alex, Brindley, Paul J

“…Minimal information on the genome and proteome of Schistosoma haematobium is available, in marked contrast to the situation with the other major species of…”
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The NIH-NIAID schistosomiasis resource center by Lewis, Fred A, Liang, Yung-San, Raghavan, Nithya, Knight, Matty

“…A bench scientist studying schistosomiasis must make a large commitment to maintain the parasite's life cycle, which necessarily involves a mammalian…”
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Schistosomiasis by Lewis, Fred A, Tucker, Matthew S

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An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection by Wynn, Thomas A, Cheever, Allen W, Jankovic, Dragana, Poindexter, Robert W, Caspar, Pat, Lewis, Fred A, Sher, Alan

“…The harmful fibrosis which often occurs in the context of infectious disease involves the excessive deposition of connective tissue matrix, particularly…”
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Ultrastructure of the Schistosoma mansoni cercaria by Dorsey, Charles H, Cousin, Carolyn E, Lewis, Fred A, Stirewalt, Margaret A

“…The cercaria of the schistosome parasite is a short-lived, free-swimming larval stage that is infective for the mammalian, definitive host. This atlas…”
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A bacterial artificial chromosome library for Biomphalaria glabrata, intermediate snail host of Schistosoma mansoni by Adema, Coen M, Luo, Mei-Zhong, Hanelt, Ben, Hertel, Lynn A, Marshall, Jennifer J, Zhang, Si-Ming, DeJong, Randall J, Kim, Hye-Ran, Kudrna, David, Wing, Rod A, Soderlund, Cari, Knight, Matty, Lewis, Fred A, Caldeira, Roberta Lima, Jannotti-Passos, Liana K, Carvalho, Omar dos Santos, Loker, Eric S

“…To provide a novel resource for analysis of the genome of Biomphalaria glabrata, members of the international Biomphalaria glabrata Genome Initiative…”
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Identification of the Boudicca and Sinbad retrotransposons in the genome of the human blood fluke Schistosoma haematobium by Copeland, Claudia S, Lewis, Fred A, Brindley, Paul J

“…Schistosomes have a comparatively large genome, estimated for Schistosoma mansoni to be about 270 megabase pairs (haploid genome). Recent findings have shown…”
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Pillars article: downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J. Exp. Med. 1991. 173: 159-166 by Pearce, Edward J, Caspar, Patricia, Grzych, Jean-Marie, Lewis, Fred A, Sher, Alan

“…In the mouse, infection with Schistosoma mansoni results in an egg-producing infection and associated disease, whereas vaccination with attenuated larval…”
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Determination and Quantification of Schistosoma mansoni Cercarial Emergence from Biomphalaria glabrata Snails by Tucker, Matthew S, Lewis, Fred A, Driver, James D, Granath, Willard O

“…Living and fixed samples of Schistosoma mansoni–infected Biomphalaria glabrata snails were used to determine the relative contributions of different snail…”
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Long-Term Genetic Stability and Population Dynamics of Laboratory Strains of Schistosoma mansoni by Blank, Walter A, Test, Matthew R, Liu, Shi Fan, Lewis, Fred A, Blanton, Ronald E

“…Measures of genetic differentiation between populations are useful tools for understanding the long-term dynamics of parasite communities. We followed the…”
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In vitro and in silico analysis of signal peptides from the human blood fluke, Schistosoma mansoni by Pearson, Mark S., McManus, Donald P., Smyth, Danielle J., Lewis, Fred A., Loukas, Alex

“…Proteins secreted by and anchored on the surfaces of parasites are in intimate contact with host tissues. The transcriptome of infective cercariae of the blood…”
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Conservation of CD4 + T cell-dependent developmental mechanisms in the blood fluke pathogens of humans by Lamb, Erika W., Crow, Emily T., Lim, K.C., Liang, Yung-san, Lewis, Fred A., Davies, Stephen J.

“…Schistosoma blood flukes are trematode parasites with a cosmopolitan distribution that infect over 200 million people globally. We previously showed that…”
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Immunity to schistosomiasis: glycans are potential antigenic targets for immune intervention by Nyame, A.Kwame, Lewis, Fred A., Doughty, Barbara L., Correa-Oliveira, Rodrigo, Cummings, Richard D.

“…The major humoral immune responses in animals infected with Schistosoma mansoni are directed toward carbohydrate antigens. Among these antigens are…”
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Comparative gene analysis of Biomphalaria glabrata hemocytes pre- and post-exposure to miracidia of Schistosoma mansoni by Raghavan, Nithya, Miller, Andre N, Gardner, Malcolm, FitzGerald, Peter C, Kerlavage, Anthony R, Johnston, David A, Lewis, Fred A, Knight, Matty

“…The internal defense mechanism of the snail Biomphalaria glabrata during a schistosome infection is activated and mediated via the immune effector cells known…”
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A laboratory-based approach to biological control of snails by Lewis, F A, Knight, M, Richards, C S

“…Development of Schistosoma mansoni in the intermediate host Biomphalaria glabrata is influenced by a number of parasite and snail genes. Understanding the…”
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Parasite-susceptibility phenotypes of F1 Biomphalaria glabrata progeny derived from interbreeding Schistosoma mansoni-resistant and -susceptible snails by LEWIS, Fred A, PATTERSON, Carolyn N, GRZYWACZ, Claudia

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Differential gene expression in haemocytes of the snail Biomphalaria glabrata: effects of Schistosoma mansoni infection by Miller, André N., Raghavan, Nithyakalyani, FitzGerald, Peter C., Lewis, Fred A., Knight, Matty

“…Parasite encapsulation and destruction in Biomphalaria glabrata has been shown to involve the cellular component of the snail's internal defence system, the…”
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The Identification of Markers Segregating with Resistance to Schistosoma mansoni Infection in the Snail Biomphalaria glabrata by Knight, Matty, Miller, Andre N., Patterson, Carolyn N., Rowe, Christopher G., Michaels, George, Carr, Daniel, Richards, Charles S., Lewis, Fred A.

“…Both snail and parasite genes determine the susceptibility of the snail Biomphalaria glabrata to infection with the trematode Schistosoma mansoni. To identify…”
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