Search Results - "Lewis, Brianne"

Hydrogen Sulfide Oxidation by Myoglobin by Bostelaar, Trever, Vitvitsky, Victor, Kumutima, Jacques, Lewis, Brianne E, Yadav, Pramod K, Brunold, Thomas C, Filipovic, Milos, Lehnert, Nicolai, Stemmler, Timothy L, Banerjee, Ruma

“…Enzymes in the sulfur network generate the signaling molecule, hydrogen sulfide (H2S), from the amino acids cysteine and homocysteine. Since it is toxic at…”
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A scoping review to identify and organize literature trends of bias research within medical student and resident education by Lewis, Brianne E, Naik, Akshata R

“…Physician bias refers to the unconscious negative perceptions that physicians have of patients or their conditions. Medical schools and residency programs…”
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A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin by Ruetz, Markus, Kumutima, Jacques, Lewis, Brianne E., Filipovic, Milos R., Lehnert, Nicolai, Stemmler, Timothy L., Banerjee, Ruma

“…Hydrogen sulfide is a critical signaling molecule, but high concentrations cause cellular toxicity. A four-enzyme pathway in the mitochondrion detoxifies H2S…”
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Inflammation at Site of Insulin Infusion Diminishes Glycemic Control by Kesserwan, Shereen, Lewis, Brianne E, Mao, Li, Sharafieh, Roshanak, Atwood, Thomas, Kreutzer, Donald L, Klueh, Ulrike

“…The approximation of euglycemia is the most effective means of preventing diabetic complications, which is achieved through effective insulin delivery. Recent…”
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Manganese co-localizes with calcium and phosphorus in Chlamydomonas acidocalcisomes and is mobilized in manganese-deficient conditions by Tsednee, Munkhtsetseg, Castruita, Madeli, Salomé, Patrice A., Sharma, Ajay, Lewis, Brianne E., Schmollinger, Stefan R., Strenkert, Daniela, Holbrook, Kristen, Otegui, Marisa S., Khatua, Kaustav, Das, Sayani, Datta, Ankona, Chen, Si, Ramon, Christina, Ralle, Martina, Weber, Peter K., Stemmler, Timothy L., Pett-Ridge, Jennifer, Hoffman, Brian M., Merchant, Sabeeha S.

“…Exposing cells to excess metal concentrations well beyond the cellular quota is a powerful tool for understanding the molecular mechanisms of metal…”
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Insulin Derived Fibrils Induce Cytotoxicity in vitro and Trigger Inflammation in Murine Models by Lewis, Brianne E., Mulka, Adam, Mao, Li, Sharafieh, Roshanak, Qiao, Yi, Kesserwan, Shereen, Wu, Rong, Kreutzer, Don, Klueh, Ulrike

“…Background: Effective exogenous insulin delivery is the cornerstone of insulin dependent diabetes mellitus management. Recent literature indicates that…”
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Characteristics of the Isu1 C-terminus in relation to [2Fe-2S] cluster assembly and ISCU Myopathy by Lewis, Brianne E., Campbell, Courtney J., Rodrigues, Andria, Thompson, Lindsey, Pandey, Ashutosh K., Gallagher, Sarah N., Pain, Debkumar, Dancis, Andrew, Stemmler, Timothy L.

“…Mitochondrial [2Fe-2S] cluster biosynthesis is driven by the coordinated activities of the Iron–Sulfur Cluster (ISC) pathway protein machinery. Within the ISC…”
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Fine-tuning of Substrate Affinity Leads to Alternative Roles of Mycobacterium tuberculosis Fe2+-ATPases by Patel, Sarju J., Lewis, Brianne E., Long, Jarukit E., Nambi, Subhalaxmi, Sassetti, Christopher M., Stemmler, Timothy L., Argüello, José M.

“…Little is known about iron efflux transporters within bacterial systems. Recently, the participation of Bacillus subtilis PfeT, a P1B4-ATPase, in cytoplasmic…”
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Examining Inclusive Language in Clinical Narratives in Medical Biochemistry Textbooks to Model Equitable Patient-Centered Care in Preclinical Undergraduate Medical Education by George, Sarah, Kim, Min Young, Naik, Akshata R., Lewis, Brianne E.

“…Purpose When healthcare professionals use biased or stigmatizing language to describe people or conditions, it can impact the quality of care or erode the…”
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Unique roles of iron and zinc binding to the yeast Fe-S cluster scaffold assembly protein "Isu1" by Lewis, Brianne E, Mason, Zachary, Rodrigues, Andria V, Nuth, Manunya, Dizin, Eric, Cowan, J. A, Stemmler, Timothy L

“…Mitochondrial Fe-S cluster biosynthesis is accomplished within yeast utilizing the biophysical attributes of the "Isu1" scaffold assembly protein. As a member…”
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Nanothermometry Reveals Calcium-Induced Remodeling of Myosin by Kuhn, Eric R, Naik, Akshata R, Lewis, Brianne E, Kokotovich, Keith M, Li, Meishan, Stemmler, Timothy L, Larsson, Lars, Jena, Bhanu P

“…Ions greatly influence protein structure–function and are critical to health and disease. A 10, 000-fold higher calcium in the sarcoplasmic reticulum (SR) of…”
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Phenolic Preservative Removal from Commercial Insulin Formulations Reduces Tissue Inflammation while Maintaining Euglycemia by Mulka, Adam, Lewis, Brianne E, Mao, Li, Sharafieh, Roshanak, Kesserwan, Shereen, Wu, Rong, Kreutzer, Donald L, Klueh, Ulrike

“…Background: Exogenous insulin therapy requires stabilization of the insulin molecule, which is achieved through the use of excipients (e.g., phenolic…”
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SAXS analysis of a soluble cytosolic NgBR construct including extracellular and transmembrane domains by Holcomb, Joshua, Doughan, Maysaa, Spellmon, Nicholas, Lewis, Brianne, Perry, Emerson, Zhang, Yingxue, Nico, Lindsey, Wan, Junmei, Chakravarthy, Srinivas, Shang, Weifeng, Miao, Qing, Stemmler, Timothy, Yang, Zhe

“…The Nogo-B receptor (NgBR) is involved in oncogenic Ras signaling through directly binding to farnesylated Ras. It recruits farnesylated Ras to the…”
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The reproductive health fall-out of a global pandemic by Thorne, Julie G., Buitendyk, Marie, Wawuda, Righa, Lewis, Brianne, Bernard, Caitlin, Spitzer, Rachel F.

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985-P: Insulin Excipient Removal Is Counterbalanced by Insulin Fibril Formation by LEWIS, BRIANNE, MULKA, ADAM, KESSERWAN, CHAFICA, KREUTZER, DON, KLUEH, ULRIKE

“…Objective: Insulin infusion pump sets are only FDA approved for 3 days as device failure often ensues from an inflammatory response driven by insulin…”
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Utilizing a medical school outreach program to help high school students explore the impact of food security and ultraprocessed foods on health risks by Kemp, Kyeorda, Lewis, Brianne, Naik, Akshata R, Uhley, Virginia E

“…We offered an enrichment program for high school students with the theme, "The Environment, Health, and You" during the Summer of 2022 and the Spring of 2023…”
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Manganese co-localizes with calcium and phosphorus in Chlamydomonas acidocalcisomes and is mobilized in manganese-deficient conditions by Tsednee, Munkhtsetseg, Castruita, Madeli, Salomé, Patrice A., Sharma, Ajay, Lewis, Brianne E., Schmollinger, Stefan R., Strenkert, Daniela, Holbrook, Kristen, Otegui, Marisa S., Khatua, Kaustav, Das, Sayani, Datta, Ankona, Chen, Si, Ramon, Christina, Ralle, Martina, Weber, Peter K., Stemmler, Timothy L., Pett-Ridge, Jennifer, Hoffman, Brian M., Merchant, Sabeeha S.

“…Exposing cells to excess metal concentrations well beyond the cellular quota is a powerful tool for understanding the molecular mechanisms of metal…”
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The reproductive health fall-out of a global pandemic by Thorne, Julie G., Buitendyk, Marie, Wawuda, Righa, Lewis, Brianne, Bernard, Caitlin, Spitzer, Rachel F.

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The Dynamic Nature and Biophysical Characterization of ISU1, Fe-S Cluster Assembly Scaffold Protein in Saccharomyces cerevisiae, and Its Significance to Human Disease by Lewis, Brianne Elizabeth

“…Mitochondrial Fe-S cluster biosynthesis is accomplished within yeast utilizing the biophysical characteristics of the “Isu1” scaffold protein. As a member of a…”
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