Search Results - "Lewis, Arthur F"

Synthesis and antiviral activity of certain guanosine analogs in the thiazolo[4,5-d]pyrimidine ring system by Kini, Ganesh D, Anderson, Jack D, Sanghvi, Yogesh S, Lewis, Arthur F, Smee, Donald F, Revankar, Ganapathi R, Robins, Roland K, Cottam, Howard B

“…Several sugar-modified nucleoside derivatives of the purine analogue 5-amino-3-beta-D-ribofuranosylthiazolo[4,5-d]pyrimidine-2,7-dione (1) were synthesized…”
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Synthesis and in vivo antitumor activity of 2-amino-9H-purine-6-sulfenamide, -sulfinamide, and -sulfonamide and related purine ribonucleosides by Revankar, Ganapathi R, Hanna, Naeem B, Imamura, Nobutaka, Lewis, Arthur F, Larson, Steven B, Finch, Rick A, Avery, Thomas L, Robins, Roland K

“…A number of 6-sulfenamide, 6-sulfinamide, and 6-sulfonamide derivatives of 2-aminopurine and certain related purine ribonucleosides have been synthesized and…”
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Pyrazolopyrimidine nucleosides. 13. Synthesis of the novel C-nucleoside 5-amino-3-(.beta.-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidin-7-one, a guanosine analog related to the nucleoside antibiotic formycin B by Lewis, Arthur F, Townsend, Leroy B

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Pyrazolo[4,3-d]pyrimidine nucleosides. 9. Studies on the isomeric N-methylformycins by Lewis, Arthur F, Townsend, Leroy B

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Molecular structure and conformation of the nucleoside antibiotic derivative 2-methylformycin with a C-glycosidic bond by Abola, Jaime E, Sims, Michael J, Abraham, Donald J, Lewis, Arthur F, Townsend, Leroy B

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Thiazolo[4,5-d]pyrimidines. Part I. synthesis and anti-human cytomegalovirus (HCMV) activity in vitro of certain alkyl derivatives by Lewis, Arthur F., Revankar, Ganapathi R., Fennewald, Susan M., Rando, Robert F., Huffman, John H.

“…Alkyl derivatives of the thiazolo[4,5‐d]pyrimidine congeners of guanine and uracil were prepared and assessed for in vitro activity against human…”
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Synthesis and in vitro anti-human cytomegalovirus (hcmv) activity of certain alkenyl substituted cytosines and 5-halocytosines by Lewis, Arthur F., Revankar, Ganapathi R., Rando, Robert F.

“…The 1‐[(Z)‐2‐penten‐1‐yl] and 1‐(3‐methyl‐2‐buten‐1‐yl) derivatives of cytosine, 5‐bromocytosine, 5‐fluorocytosine, and 5‐iodocytosine were prepared by a…”
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Synthesis of certain N- and C-alkyl purine analogs by Bhattacharya, Birendra K., Rao, T. Sudhakar, Lewis, Arthur F., Revankar, Ganapathi R., Sanghvi, Yogesh S., Robins, Roland K.

“…A number of N‐ and C‐alkyl derivatives of selected guanine analogs have been synthesized as potential antiviral agents. n‐Pentyl, n‐hexyl and 6‐hydroxyhexyl…”
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2′-O,5-dimethyluridine: A total synthesis and single crystal X-ray diffraction study by Lewis, Arthur F., Revankar, Ganapathi R., Hogan, Michael E.

“…A new method for the synthesis of 2′‐O,5‐dimethyluridine (5) has provided the title compound in a higher yield. Application of a one‐pot ribosylation…”
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Derivatives of the nucleoside antibiotics, toyocamycin and sangivamycin analogs of N 6 ‐(Δ 2 ‐isopentenyl)adenosine by Lewis, Arthur F., Townsend, Leroy B.

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Synthesis of 4-amino-3-(β-D-ribofuranosyl)pyrazole-5-carboxarnidc via ring fission of formycin derivatives and purification using high pressure liquid chromatography by Lewis, Arthur F., Long, Robert A., Roti, Linda W. Roti, Townsend, Leroy B.

“…Two methods have been established for the synthesis of 4‐amino‐3‐(β‐ D‐ribofuranosyl )‐pyrazole‐5‐carboxamide. This nucleoside ean be viewed as a potentially…”
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Derivatives of the nucleoside antibiotics, toyocamycin and sangivamycin analogs of N6 -(Δ2-isopentenyl)adenosine by Lewis, Arthur F., Townsend, Leroy B.

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Sequence-specific inhibition of the tumor necrosis factor-alpha receptor I gene by oligodeoxynucleotides containing N7 modified 2'-deoxyguanosine by Ojwang, J O, Lewis, A F, Revankar, G R, Walker, D, Akiyama, T, Hogan, M E, Rando, R F

“…Tumor necrosis factor-alpha (TNF-alpha) is a highly pleiotropic cytokine produced mainly by activated macrophages. This cytokine has been found to mediate the…”
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Mass spectra of C-nucleosides II. An unusual fragmentation reaction of the heterocyclic moiety of pyrazomycin and some closely related compounds by Crain, P. F., McCloskey, James A., Lewis, Arthur F., Schram, Karl H., Townsend, Leroy B.

“…The mass spectrum of pyrazomycin has been obtained and reveals a fragmentation pattern with several important peaks which are not normally found in the mass…”
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Structure of the nucleoside antibiotics formycin, formyein B and laurusin by Robins, Roland K., Townsend, Leroy B., Cassidy, Frederick, Gerster, John F., Lewis, Arthur F., Miller, Richard L.

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