Search Results - "Lewis, Andrew L"
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Aqueous Dispersion Polymerization: A New Paradigm for in Situ Block Copolymer Self-Assembly in Concentrated Solution
Published in Journal of the American Chemical Society (05-10-2011)“…Reversible addition–fragmentation chain transfer polymerization has been utilized to polymerize 2-hydroxypropyl methacrylate (HPMA) using a water-soluble…”
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Effect of Salt on Phosphorylcholine-based Zwitterionic Polymer Brushes
Published in Langmuir (24-05-2016)“…A quantitative investigation of the responses of surface-grown biocompatible brushes of poly(2-(methacryloyloxy)ethyl phosphorylcholine) (PMPC) to different…”
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Controlling Cellular Uptake by Surface Chemistry, Size, and Surface Topology at the Nanoscale
Published in Small (Weinheim an der Bergstrasse, Germany) (02-11-2009)“…Cell cytosol and the different subcellular organelles house the most important biochemical processes that control cell functions. Effective delivery of…”
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Effect of pH and Temperature on PMPC–PDPA Copolymer Self-Assembly
Published in Macromolecules (26-02-2013)“…The effect of temperature on a pH-responsive amphiphilic diblock copolymer, namely poly(2-(methacryloyloxy)ethyl…”
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Characterization of a novel intrinsically radiopaque Drug-eluting Bead for image-guided therapy: DC Bead LUMI
Published in Journal of controlled release (28-03-2017)“…We have developed a straightforward and efficient method of introducing radiopacity into Polyvinyl alcohol (PVA)-2-Acrylamido-2-methylpropane sulfonic acid…”
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One-Pot Synthesis of Biomimetic Shell Cross-Linked Micelles and Nanocages by ATRP in Alcohol/Water Mixtures
Published in Angewandte Chemie (International ed.) (03-05-2010)“…Shell shock: The one‐pot synthesis of shell cross‐linked (SCL) micelles was achieved using an ABC triblock copolymer in a 9:1 alcohol/water mixture. These SCL…”
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A New Class of Biochemically Degradable, Stimulus-Responsive Triblock Copolymer Gelators
Published in Angewandte Chemie International Edition (19-05-2006)“…To rub gel into the wound: A thermoresponsive ABA triblock copolymer gelator with A=N‐isopropylacrylamide and B=2‐(methacryloyloxy)ethyl phosphorylcholine has…”
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Review of the Development of Methods for Characterization of Microspheres for Use in Embolotherapy: Translating Bench to Cathlab
Published in Advanced healthcare materials (01-05-2017)“…Therapeutic embolotherapy is the deliberate occlusion of a blood vessel within the body, which can be for the prevention of internal bleeding, stemming of flow…”
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Quantitative Evaluation of Mechanosensing of Cells on Dynamically Tunable Hydrogels
Published in Journal of the American Chemical Society (09-02-2011)“…Thin hydrogel films based on an ABA triblock copolymer gelator [where A is pH-sensitive poly(2-(diisopropylamino)ethyl methacrylate) (PDPA) and B is…”
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Controlling Polymersome Surface Topology at the Nanoscale by Membrane Confined Polymer/Polymer Phase Separation
Published in ACS nano (22-03-2011)“…Nature has the exquisite ability to design specific surface patterns and topologies on both the macro- and nanolength scales that relate to precise functions…”
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Advancements in the development on new liquid embolic agents for use in therapeutic embolisation
Published in Journal of materials chemistry. B, Materials for biology and medicine (23-09-2020)“…Liquid formulations have a well-established role in therapeutic embolisation of blood vessels with the widespread use of cyanoacrylate glues, precipitating…”
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Drug-eluting Beads for Liver Embolization: Concentration of Doxorubicin in Tissue and in Beads in a Pig Model
Published in Journal of vascular and interventional radiology (01-02-2010)“…Purpose To evaluate the local tissue concentrations of the antineoplastic agent doxorubicin and the amount of drug still present inside drug delivery…”
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Biocompatible Wound Dressings Based on Chemically Degradable Triblock Copolymer Hydrogels
Published in Biomacromolecules (01-08-2008)“…The synthesis of a series of thermo-responsive ABA triblock copolymers in which the outer A blocks comprise poly(2-hydroxypropyl methacrylate) and the central…”
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In vitro characterization of immune modulating drug-eluting immunobeads towards transarterial embolization in cancer
Published in Scientific reports (19-12-2022)“…Hepatocellular carcinoma (HCC) is an aggressive liver cancer with limited effective treatment options. In this study, we selected TLR agonists imiquimod (IMQ),…”
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In vitro and preclinical assessment of an intranasal spray formulation of parathyroid hormone PTH 1–34 for the treatment of osteoporosis
Published in International journal of pharmaceutics (15-01-2018)“…[Display omitted] •Nasal spray formulations of PTH 1–34 containing absorption enhancers, either Solutol® HS15, poloxamer 407, chitosan or sodium hyaluronate,…”
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Live cell imaging of membrane / cytoskeleton interactions and membrane topology
Published in Scientific reports (10-09-2014)“…We elucidate the interaction between actin and specific membrane components, using real time live cell imaging, by delivering probes that enable access to…”
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Radiopaque Drug-Eluting Beads for Transcatheter Embolotherapy: Experimental Study of Drug Penetration and Coverage in Swine
Published in Journal of vascular and interventional radiology (01-02-2012)“…Abstract Purpose To determine local doxorubicin levels surrounding radiopaque drug-eluting beads (DEBs) in normal swine liver and kidney following…”
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Frequent mechanical stress suppresses proliferation of mesenchymal stem cells from human bone marrow without loss of multipotency
Published in Scientific reports (15-04-2016)“…Mounting evidence indicated that human mesenchymal stem cells (hMSCs) are responsive not only to biochemical but also to physical cues, such as substrate…”
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Author Correction: In vitro characterization of immune modulating drug-eluting immunobeads towards transarterial embolization in cancer
Published in Scientific reports (02-03-2023)Get full text
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Synthesis, characterization, and imaging of radiopaque bismuth beads for image-guided transarterial embolization
Published in Scientific reports (12-01-2021)“…Current therapy for hypervascular cancers, e.g., hepatocellular carcinoma, includes occlusion of the tumor blood supply by arterial infusion of embolic…”
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