Search Results - "Lewis, Amanda J."

Alterations in Sub-Axonal Architecture Between Normal Aging and Parkinson's Diseased Human Brains Using Label-Free Cryogenic X-ray Nanotomography by Tran, Hung Tri, Tsai, Esther H R, Lewis, Amanda J, Moors, Tim, Bol, J G J M, Rostami, Iman, Diaz, Ana, Jonker, Allert J, Guizar-Sicairos, Manuel, Raabe, Joerg, Stahlberg, Henning, van de Berg, Wilma D J, Holler, Mirko, Shahmoradian, Sarah H

“…Gaining insight to pathologically relevant processes in continuous volumes of unstained brain tissue is important for a better understanding of neurological…”
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Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes by Shahmoradian, Sarah H., Lewis, Amanda J., Genoud, Christel, Hench, Jürgen, Moors, Tim E., Navarro, Paula P., Castaño-Díez, Daniel, Schweighauser, Gabriel, Graff-Meyer, Alexandra, Goldie, Kenneth N., Sütterlin, Rosmarie, Huisman, Evelien, Ingrassia, Angela, Gier, Yvonne de, Rozemuller, Annemieke J. M., Wang, Jing, Paepe, Anne De, Erny, Johannes, Staempfli, Andreas, Hoernschemeyer, Joerg, Großerüschkamp, Frederik, Niedieker, Daniel, El-Mashtoly, Samir F., Quadri, Marialuisa, Van IJcken, Wilfred F. J., Bonifati, Vincenzo, Gerwert, Klaus, Bohrmann, Bernd, Frank, Stephan, Britschgi, Markus, Stahlberg, Henning, Van de Berg, Wilma D. J., Lauer, Matthias E.

“…Parkinson’s disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Key neuropathological…”
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Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy by Böing, Carolin, Di Fabrizio, Marta, Burger, Domenic, Bol, John G J M, Huisman, Evelien, Rozemuller, Annemieke J M, van de Berg, Wilma D J, Stahlberg, Henning, Lewis, Amanda J

“…Multiple System Atrophy is characterized pathologically by the accumulation of alpha-synuclein (aSyn) into glial cytoplasmic inclusions (GCIs). The mechanism…”
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Imaging of post-mortem human brain tissue using electron and X-ray microscopy by Lewis, Amanda J, Genoud, Christel, Pont, Mélissa, van de Berg, Wilma DJ, Frank, Stephan, Stahlberg, Henning, Shahmoradian, Sarah H, Al-Amoudi, Ashraf

“…•Ultrastructural imaging of PMHB provides novel insights into neurodegenerative disease.•Electron microscopy is a powerful tool for detailed (3D) structural…”
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Top-down knowledge modulates onset capture in a feedforward manner by Becker, Stefanie I., Lewis, Amanda J., Axtens, Jenna E.

“…How do we select behaviourally important information from cluttered visual environments? Previous research has shown that both top-down, goal-driven factors…”
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Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions by Lam, Isabel, Ndayisaba, Alain, Lewis, Amanda J, Fu, YuHong, Sagredo, Giselle T, Kuzkina, Anastasia, Zaccagnini, Ludovica, Celikag, Meral, Sandoe, Jackson, Sanz, Ricardo L, Vahdatshoar, Aazam, Martin, Timothy D, Morshed, Nader, Ichihashi, Toru, Tripathi, Arati, Ramalingam, Nagendran, Oettgen-Suazo, Charlotte, Bartels, Theresa, Boussouf, Manel, Schäbinger, Max, Hallacli, Erinc, Jiang, Xin, Verma, Amrita, Tea, Challana, Wang, Zichen, Hakozaki, Hiroyuki, Yu, Xiao, Hyles, Kelly, Park, Chansaem, Wang, Xinyuan, Theunissen, Thorold W, Wang, Haoyi, Jaenisch, Rudolf, Lindquist, Susan, Stevens, Beth, Stefanova, Nadia, Wenning, Gregor, van de Berg, Wilma D J, Luk, Kelvin C, Sanchez-Pernaute, Rosario, Gómez-Esteban, Juan Carlos, Felsky, Daniel, Kiyota, Yasujiro, Sahni, Nidhi, Yi, S Stephen, Chung, Chee Yeun, Stahlberg, Henning, Ferrer, Isidro, Schöneberg, Johannes, Elledge, Stephen J, Dettmer, Ulf, Halliday, Glenda M, Bartels, Tim, Khurana, Vikram

“…The heterogeneity of protein-rich inclusions and its significance in neurodegeneration is poorly understood. Standard patient-derived iPSC models develop…”
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FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade by De Rossi, Pierre, Lewis, Amanda J, Furrer, Johanna, De Vos, Laura, Demeter, Tomas, Zbinden, Aurélie, Zhong, Weijia, Wiersma, Vera I, Scialo, Carlo, Weber, Julien, Guo, Zhongning, Scaramuzza, Stefano, Di Fabrizio, Marta, Böing, Carolin, Castaño-Díez, Daniel, Al-Amoudi, Ashraf, Pérez-Berlanga, Manuela, Lashley, Tammaryn, Stahlberg, Henning, Polymenidou, Magdalini

“…Morphologically distinct TDP-43 aggregates occur in clinically different FTLD-TDP subtypes, yet the mechanism of their emergence and contribution to clinical…”
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Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles by Navarro, Paula P., Genoud, Christel, Castaño-Díez, Daniel, Graff-Meyer, Alexandra, Lewis, Amanda J., de Gier, Yvonne, Lauer, Matthias E., Britschgi, Markus, Bohrmann, Bernd, Frank, Stephan, Hench, Jürgen, Schweighauser, Gabriel, Rozemuller, Annemieke J. M., van de Berg, Wilma D. J., Stahlberg, Henning, Shahmoradian, Sarah H.

“…Corpora amylacea are cell-derived structures that appear physiologically in the aged human brain. While their histological identification is straightforward,…”
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Maximizing case acceptance: a case report by Lewis, Amanda J

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