Search Results - "Lewington, Andrew J P"

Raising awareness of acute kidney injury: a global perspective of a silent killer by Lewington, Andrew J P, Cerdá, Jorge, Mehta, Ravindra L

“…Worldwide, acute kidney injury (AKI) is associated with poor patient outcomes. Over the last few years, collaborative efforts, enabled by a common definition…”
Get more information

A systematic analysis of the effects of increasing degrees of serum immunodepletion in terms of depth of coverage and other key aspects in top-down and bottom-up proteomic analyses by Smith, Matthew P. Welberry, Wood, Steven L., Zougman, Alexandre, Ho, Jenny T. C., Peng, Jianhe, Jackson, David, Cairns, David A., Lewington, Andrew J. P., Selby, Peter J., Banks, Rosamonde E.

“…Immunodepletion of clinical fluids to overcome the dominance by a few very abundant proteins has been explored but studies are few, commonly examining only…”
Get full text

Alemtuzumab Induction in Renal Transplantation Permits Safe Steroid Avoidance with Tacrolimus Monotherapy: A Randomized Controlled Trial by Welberry Smith, Matthew P, Cherukuri, Aravind, Newstead, Chas G, Lewington, Andrew J.P, Ahmad, Niaz, Menon, Krish, Pollard, Stephen G, Prasad, Padmini, Tibble, Steve, Giddings, Emma, Baker, Richard J

“…BACKGROUNDThe use of alemtuzumab as induction immunosuppression for renal transplantation introduces the possibility of long-term tacrolimus monotherapy,…”
Get full text

The Clinical Significance of Early Proteinuria After Renal Transplantation by CHERUKURI, Aravind, WELBERRY-SMITH, Matthew P, TATTERSALL, James E, AHMAD, Niaz, NEWSTEAD, Chas G, LEWINGTON, Andrew J. P, BAKER, Richard J

“…Late-onset proteinuria after renal transplantation has been universally associated with poor allograft outcomes. However, the significance of early low-grade…”
Get full text

Quality Improvement Goals for Acute Kidney Injury by Kashani, Kianoush, Rosner, Mitchell Howard, Haase, Michael, Lewington, Andrew J P, O'Donoghue, Donal J, Wilson, F Perry, Nadim, Mitra K, Silver, Samuel A, Zarbock, Alexander, Ostermann, Marlies, Mehta, Ravindra L, Kane-Gill, Sandra L, Ding, Xiaoqiang, Pickkers, Peter, Bihorac, Azra, Siew, Edward D, Barreto, Erin F, Macedo, Etienne, Kellum, John A, Palevsky, Paul M, Tolwani, Ashita Jiwat, Ronco, Claudio, Juncos, Luis A, Rewa, Oleksa G, Bagshaw, Sean M, Mottes, Theresa Ann, Koyner, Jay L, Liu, Kathleen D, Forni, Lui G, Heung, Michael, Wu, Vin-Cent

“…AKI is a global concern with a high incidence among patients across acute care settings. AKI is associated with significant clinical consequences and increased…”
Get full text

Application of proteomic analysis to the study of renal diseases by Smith, Matthew P. Welberry, Banks, Rosamonde E, Wood, Steven L, Lewington, Andrew J. P, Selby, Peter J

“…Proteomic research has the potential to provide disease biomarkers to clinical practice and insight into pathological mechanisms. In this Review, Welberry…”
Get full text

Poor Tolerance of Sirolimus in a Steroid Avoidance Regimen for Renal Transplantation by WELBERRY SMITH, Matthew P, NEWSTEAD, Chas G, AHMAD, Niaz, LEWINGTON, Andrew J. P, TIBBIE, Stephen, LODGE, J. Peter A, POLLARD, Stephen G, BAKER, Richard J

“…Vascular disease and chronic allograft nephropathy have prompted re-evaluation of steroids and calcineurin inhibitors (CNIs) in renal transplantation…”
Get full text

The Outcomes of Critically Ill Patients with Acute Kidney Injury Receiving Renal Replacement Therapy by Lines, Simon W., Cherukuri, Aravind, Murdoch, Stuart D., Bellamy, Mark C., Lewington, Andrew J.P.

“…Introduction Acute kidney injury (AKI) is common among critically ill patients and associated with a high mortality. We report here on the outcomes of patients…”
Get full text

Community Health Care Quality Standards to Prevent Acute Kidney Injury and Its Consequences by Silver, Samuel A., Nadim, Mitra K., O'Donoghue, Donal J., Wilson, Francis P., Kellum, John A., Mehta, Ravindra L., Ronco, Claudio, Kashani, Kianoush, Rosner, Mitchell H., Haase, Michael, Lewington, Andrew J.P.

“…As the incidence of acute kidney injury (AKI) increases, prevention strategies are needed across the health care continuum, which begins in the community…”
Get full text

Serum aminoacylase-1 is a novel biomarker with potential prognostic utility for long-term outcome in patients with delayed graft function following renal transplantation by Welberry Smith, Matthew P, Zougman, Alexandre, Cairns, David A, Wilson, Michelle, Wind, Tobias, Wood, Steven L, Thompson, Douglas, Messenger, Michael P, Mooney, Andrew, Selby, Peter J, Lewington, Andrew J P, Banks, Rosamonde E

“…Early identification and prognostic stratification of delayed graft function following renal transplantation has significant potential to improve outcome. Mass…”
Get more information

Relationship between patients' outcomes and the changes in serum creatinine and urine output and RIFLE classification in a large critical care cohort database by Harris, Steve K, Lewington, Andrew J P, Harrison, David A, Rowan, Kathy M

“…We report the stepwise application of the RIFLE classification in 155,624 admissions in the UK Intensive Care National Audit & Research Centre Case Mix…”
Get more information

Renal Transplantation From Pediatric Donors in the United Kingdom by Dave, Rajiv V, Hakeem, Abdul R, Dawrant, Michael J, Ecuyer, Clare L, Lewington, Andrew J P, Attia, Magdy S, Hostert, Lutz, Finlay, Eric, Ahmad, Niaz

“…Significant disparity exists in the United Kingdom between the need for organ transplant and supply of deceased donor organs. In the recent years, efforts to…”
Get full text

Detection of patients with acute kidney injury by the clinical laboratory using rises in serum creatinine: comparison of proposed definitions and a laboratory delta check by Garner, Ashley E, Lewington, Andrew J P, Barth, Julian H

“…Timely detection of acute kidney injury (AKI) in hospital patients has been hampered by the multiple definitions of AKI and difficulties applying their…”
Get more information

Acute kidney injury: how do we define it? by Lewington, Andrew J P, Sayed, Ahmed

“…Over recent years, there has been welcome increased interest in acute kidney injury (AKI) and its association with patient outcome. The term AKI has replaced…”
Get more information

Invited manuscript poster on renal-related education American Society of Nephrology, Nov. 16-21, 2010. Do medical trainees receive adequate training in the management of acute kidney injury? by Ali, Mansoor N, Lewington, Andrew J P

“…There has been increased interest in acute kidney injury (AKI) over the past decade following the recognition of the association of relatively small rises in…”
Get more information

Inhibition of poly(ADP-ribose) polymerase attenuates ischemic renal injury in rats by Martin, D R, Lewington, A J, Hammerman, M R, Padanilam, B J

“…The enzyme, poly(ADP-ribose) polymerase (PARP), effects repair of DNA after ischemia-reperfusion (I/R) injury to cells in nerve and muscle tissue. However, its…”
Get more information

Dipstick test for myoglobinuria by Lines, Simon W, Lewington, Andrew J P

Get full text

Expression of CD44 in kidney after acute ischemic injury in rats by Lewington, A J, Padanilam, B J, Martin, D R, Hammerman, M R

“…De novo CD44 and ligand expression at wound margins accompanies cellular proliferation and migration that effect repair of injured mucosal and vascular…”
Get more information

A systematic analysis of the effects of increasing degrees of serum immunodepletion in terms of depth of coverage and other key aspects in top-down and bottom-up proteomic analyses by Smith, Matthew P. Welberry, Wood, Steven L., Zougman, Alexandre, Ho, Jenny T. C., Peng, Jianhe, Jackson, David, Cairns, David A., Lewington, Andrew J. P., Selby, Peter J., Banks, Rosamonde E.

“…This article was originally published in Proteomics 2011, 11, 2222–2235, DOI 10.1002/pmic.201100005…”
Get full text

Massive aneurysmal dilatation of a depopulated ureteric hemodialysis xenograft by SMITH, Matthew P. WELBERRY, SPARK, James Ian, PATEL, Jai V., BORDER, David J., OSWAL, Dilip, LEWINGTON, Andrew J. P.

“…Use of depopulated bovine ureteric xenografts for hemodialysis vascular access has recently been described. Cellular components have been removed, giving a…”
Get full text